Diphtheria differential diagnosis: Difference between revisions
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*[[Infectious mononucleosis]] due to [[EBV]] | *[[Infectious mononucleosis]] due to [[EBV]] | ||
*Group A [[streptococci]] [[pharyngitis]] | *Group A [[streptococci]] [[pharyngitis]] | ||
*[[Epiglottitis]] due to | *[[Epiglottitis]] due to [[Hemophilus influenza]] type b | ||
*Viral [[pharyngitis]] due to [[influenza]], [[HSV]] or [[adenovirus]] | *Viral [[pharyngitis]] due to [[influenza]], [[HSV]] or [[adenovirus]] | ||
*[[Vincent's angina]] | *[[Vincent's angina]] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
Respiratory diphtheria must be differentiated from respiratory tract or other infections that present with fever, neck swelling, cough and/or pharyngeal exudates. Cutaneous diphtheria must be differentiated from other bacterial and fungal causes of skin ulceration.
Differentiating diphtheria from other diseases
Differentiating respiratory diphtheria from other diseases
A group of respiratory diseases can present with symptoms such as fever, sore throat, pharyngeal exudates and/or neck swelling, which may mimic the symptoms of a diphtheria infection. These include:[1]
- Infectious mononucleosis due to EBV
- Group A streptococci pharyngitis
- Epiglottitis due to Hemophilus influenza type b
- Viral pharyngitis due to influenza, HSV or adenovirus
- Vincent's angina
- Oral candidiasis
Differentiating cutaneous diphtheria from other diseases
Cutaneous diphtheria due to Corynebacterium diphtheria must be differentiated from other bacterial and fungal diseases that present with a shallow ulcer on the skin:[2]
- Bacterial causes:
- Pyoderma due to Staphylococcus aureus or Group A beta-hemolytic streptococci
- Cutaneous Leishmaniasis
- Cutaneous Anthrax due to Bacillus Anthracis
- Cutaneous mycobacterial infections due to Mycobacterium tuberculosis, Mycobacterium marinum or Mycobacterium ulcerans
- Fungal causes:
References
- ↑ Center for Disease Control and Prevention https://www.cdc.gov/diphtheria/downloads/dip-cklist-diag.pdf Accessed on Oct. 7, 2016.
- ↑ Zeegelaar JE, Faber WR (2008). "Imported tropical infectious ulcers in travelers". Am J Clin Dermatol. 9 (4): 219–32. PMID 18572973.