Multiple pulmonary nodules

Pulmonary Nodule Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Luke Rusowicz-Orazem, B.S.

Overview

Common causes of multiple pulmonary nodules include pulmonary neoplasms and tumor metastasis from outside of the lungs. These causes are life-threatening and should be promptly differentiated from benign neoplasms and non-fatal infectious causes. Additional life threatening causes that present with multiple pulmonary nodules include cardio-pulmonary conditions, such as aneurysm and infarction. Additional causes include granulomas.

Causes

Life Threatening Causes

• Adenocarcinoma
• Aneurysm of the pulmonary artery
• Blastoma
• Breast cancer
• Bronchial adenoma
• Bronchogenic carcinoma
• Carcinoid tumor
• Gastric cancer
• Lung metastases
• Lymphoma
• Metastasis
• Multiple myeloma
• Neurofibroma
• Neurogenic tumor
• Non-hodgkin lymphoma
• Non-small cell lung cancer
• Primary lung cancer
• Progressive massive fibrosis
• Prostate cancer
• Pulmonary arterio-venous malformation
• Pulmonary infarction
• Pulmonary sarcoma
• Sarcoma

Common Causes

• Primary lung cancer
  • Non-small cell lung cancer
  • Small cell lung cancer

• Lymphoma
• Carcinoid tumor
• Pulmonary sarcoma

Causes by Organ System

Cardiovascular	Aneurysm of the pulmonary artery, Arteriovenous malformation, Infarction zone, Pulmonary arterio-venous malformation, Pulmonary embolism, Pulmonary infarction, Varicose pulmonary vein, Vascular
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	No underlying causes
Ear Nose Throat	No underlying causes
Endocrine	Non-hodgkin lymphoma, Thyroid cancer
Environmental	Black lung disease
Gastroenterologic	Gastric cancer
Genetic	No underlying causes
Hematologic	Aneurysm of the pulmonary artery, Hemangioma, Hematoma, Non-hodgkin lymphoma, Pulmonary hamartoma
Iatrogenic	No underlying causes
Infectious Disease	Bronchogenic carcinoma
Musculoskeletal/Orthopedic	Multiple myeloma
Neurologic	Aneurysm of the pulmonary artery, Arteriovenous malformation, Neurofibroma, Neurogenic tumor
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	Breast cancer
Oncologic	Adenocarcinoma , Blastoma, Breast cancer, Bronchial adenoma, Bronchogenic carcinoma, Cancers, Carcinoid tumor, Chondroma, Gastric cancer, Granuloma, Hamartoma, Hamartomatosis, Hemangioma, Hematoma, Hypernephroma, Large cell lung carcinoma, Lymphoma, Metastasis, Multiple myeloma, Neurogenic tumor, Non-hodgkin lymphoma, Non-small cell lung cancer, Primary lung cancer, Prostate cancer, Pulmonary sarcoma, Sarcoma, Seminoma, Small cell lung cancer, Squamous cell carcinoma, Thyroid cancer
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	Amyloidosis, Aneurysm of the pulmonary artery, Black lung disease, Bronchial adenoma, Bronchogenic carcinoma, Infarction zone, Large cell lung carcinoma, Lung abscess, Lung cavity, Lung metastases, Non-small cell lung cancer, Primary lung cancer, Pulmonary arterio-venous malformation, Pulmonary embolism, Pulmonary infarction, Pulmonary sarcoma, Sarcoidosis, Small cell lung cancer, Varicose pulmonary vein, Vascular, Wegener's granulomatosis
Renal/Electrolyte	Hypernephroma
Rheumatology/Immunology/Allergy	Amyloidosis, Churg-strauss syndrome, Fibroma, Granuloma, Hamartoma, Immunological, Neurofibroma, Progressive massive fibrosis, Rheumatoid arthritis, Rheumatoid disease, Sarcoidosis, Wegener's granulomatosis
Sexual	No underlying causes
Trauma
Urologic	Prostate cancer
Miscellaneous	No underlying causes

Causes in Alphabetical Order

• Adenocarcinoma
• Amyloidosis
• Aneurysm of the pulmonary artery
• Arteriovenous malformation
• Black lung disease
• Blastoma
• Breast cancer
• Bronchial adenoma
• Bronchogenic carcinoma
• Carcinoid tumor
• Chondroma
• Churg-strauss syndrome
• Fibroma
• Gastric cancer
• Granuloma
• Hamartomatosis
• Hemangioma
• Hematoma
• Hypernephroma
• Immunological
• Large cell lung carcinoma
• Lung metastases
• Lymphoma
• Metastasis
• Multiple myeloma
• Neurofibroma
• Neurogenic tumor
• Non-Hodgkin's Lymphoma
• Non-small cell lung cancer
• Primary lung cancer
• Progressive massive fibrosis
• Prostate cancer
• Pulmonary arterio-venous malformation
• Pulmonary infarction
• Pulmonary sarcoma
• Rheumatoid arthritis
• Rheumatoid disease
• Sarcoidosis
• Sarcoma
• Seminoma
• Small cell lung cancer
• Squamous cell carcinoma
• Thyroid cancer
• Varicose pulmonary vein
• Vascular
• Wegener's granulomatosis