Hypothyroidism causes: Difference between revisions
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==Overview== | ==Overview== | ||
==Causes== | ==Causes== | ||
<div style="-webkit-user-select: none;"> | <div style="-webkit-user-select: none;"> | ||
The most common cause of hypothyroidism is thyroiditis. Swelling and inflammation damage the thyroid gland's cells. | |||
Causes of this problem include: | |||
* The immune system attacking the thyroid gland | |||
* Viral infections (common cold) or other respiratory infections | |||
* Pregnancy (often called postpartum thyroiditis) | |||
Other causes of hypothyroidism include: | |||
* Certain medicines, such as lithium and amiodarone | |||
* Congenital (birth) defects | |||
* Radiation treatments to the neck or brain to treat different cancers | |||
* Radioactive iodine used to treat an overactive thyroid gland | |||
* Surgical removal of part or all of the thyroid gland | |||
* Sheehan syndrome, a condition that may occur in a woman who bleeds severely during pregnancy or childbirth and causes the destruction of the pituitary gland | |||
* Pituitary tumor or pituitary surgery | |||
===Life Threatening Causes=== | ===Life Threatening Causes=== | ||
*[[Aneurysm]] | *[[Aneurysm]] | ||
Line 28: | Line 44: | ||
*[[Tsh deficiency]] | *[[Tsh deficiency]] | ||
===Causes by Organ System=== | ===Causes by Organ System=== | ||
{|style="width:80%; height:100px" border="1" | {| style="width:80%; height:100px" border="1" | ||
| | | style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular''' | ||
| | | style="width:75%" bgcolor="Beige" ; border="1" | [[Alström syndrome]], [[Aneurysm of the internal carotid artery]], [[Neutral lipid storage disease ]] | ||
|- | |- | ||
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning''' | | bgcolor="LightSteelBlue" | '''Chemical/Poisoning''' | ||
|bgcolor="Beige"| [[Iodine 131]], [[Iodine antenatal infection ]], [[Iron overload ]], [[Isolated tsh deficiency]], [[Lithium]], [[Potassium iodide]] | | bgcolor="Beige" | [[Iodine 131]], [[Iodine antenatal infection ]] , [[Iron overload ]] , [[Isolated tsh deficiency]], [[Lithium]], [[Potassium iodide]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Dental''' | | '''Dental''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Dermatologic''' | | '''Dermatologic''' | ||
|bgcolor="Beige"| [[Dermatosclerosis]] | | bgcolor="Beige" | [[Dermatosclerosis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Drug Side Effect''' | | '''Drug Side Effect''' | ||
|bgcolor="Beige"| [[Aminoglutethimide]], [[Amiodarone]], [[Antithyroid drugs]], [[Atezolizumab]], [[Axitinib]], [[Bexarotene]], [[Bromide ]], [[Carbimazole]], [[Catch 22 ]], [[Ed-in-sol]], [[Ethionamide]], [[Femiron]], [[Feosol]], [[Feostat]], [[Feratab]], [[Fer-gen-sol]], [[Fergon]], [[Fer-in-sol]], [[Ferrex]], [[Hytinic]], [[Icar]], [[Interferon alfacon-1]], [[Interferon alpha]], [[Interferon-alfa]], [[Interleukin-2]], [[Ircon]], [[Methimazole]], [[Mitotane]], [[Nephro-fer]], [[Niferex]], [[Nivolumab]], [[Nu-iron]], [[Oxcarbazepine]], [[Para-amino salicylic acid]], [[Peginterferon beta-1a]], [[Pegylated interferon alfa-2b]], [[Pembrolizumab]], [[Perchlorate]], [[Pergolide]], [[Phenytoin and levothyroxine interaction]], [[Pramipexole]], [[Propylthiouracil]], [[Slow-fe]], [[Sorafenib]], [[Thionamides]], [[Thyroid and cholestyramine interaction]], [[Tiagabine]], [[Tocilizumab]], [[Tositumomab iodine-131]], [[Ttf-1]], [[Ttf-2]], [[Tyrosine kinase inhibitors]], [[Vitron-c]] | | bgcolor="Beige" | [[Aminoglutethimide]], [[Amiodarone]], [[Antithyroid drugs]], [[Atezolizumab]], [[Axitinib]], [[Bexarotene]], [[Bromide ]] , [[Carbimazole]], [[Catch 22 ]] , [[Ed-in-sol]], [[Ethionamide]], [[Femiron]], [[Feosol]], [[Feostat]], [[Feratab]], [[Fer-gen-sol]], [[Fergon]], [[Fer-in-sol]], [[Ferrex]], [[Hytinic]], [[Icar]], [[Interferon alfacon-1]], [[Interferon alpha]], [[Interferon-alfa]], [[Interleukin-2]], [[Ircon]], [[Methimazole]], [[Mitotane]], [[Nephro-fer]], [[Niferex]], [[Nivolumab]], [[Nu-iron]], [[Oxcarbazepine]], [[Para-amino salicylic acid]], [[Peginterferon beta-1a]], [[Pegylated interferon alfa-2b]], [[Pembrolizumab]], [[Perchlorate]], [[Pergolide]], [[Phenytoin and levothyroxine interaction]], [[Pramipexole]], [[Propylthiouracil]], [[Slow-fe]], [[Sorafenib]], [[Thionamides]], [[Thyroid and cholestyramine interaction]], [[Tiagabine]], [[Tocilizumab]], [[Tositumomab iodine-131]], [[Ttf-1]], [[Ttf-2]], [[Tyrosine kinase inhibitors]], [[Vitron-c]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Ear Nose Throat''' | | '''Ear Nose Throat''' | ||
|bgcolor="Beige"| [[Bilateral abductor vocal cord paralysis syndrome ]] | | bgcolor="Beige" | [[Bilateral abductor vocal cord paralysis syndrome ]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Endocrine''' | | '''Endocrine''' | ||
|bgcolor="Beige"| [[Abnormal maternal iodine levels]], [[Acth deficiency]], [[Antithyroid drugs]], [[Apeced syndrome]], [[Autoimmune polyendocrine syndrome type 3]], [[Autoimmune thyroiditis]], [[Brain-lung-thyroid syndrome]], [[Central hypothyroidism]], [[Chronic autoimmune thyroiditis]], [[Combined pituitary hormone deficiency 1 (pou1f1 gene)]], [[Combined pituitary hormone deficiency 2 (prop1 gene)]], [[Combined pituitary hormone deficiency 3 (lhx gene)]], [[Congenital disorder of glycosylation type 1a ]], [[Congenital disorder of glycosylation type 1h ]], [[Congenital thyroid dysgenesis]], [[Cretinism athyreotic ]], [[De quervain thyroiditis]], [[Deficiency of pit1]], [[Dopamine]], [[Empty sella]], [[Escamilla-lisser syndrome ]], [[Fibrous thyroiditis]], [[Goiter ]], [[Graves disease ]], [[Hashimoto's thyroiditis]], [[Hemochromatosis]], [[Hyperthyroidism ]], [[Hypoadrenocorticism ]], [[Hypomelia ]], [[Hypopituitarism]], [[Hypothalamic dysfunction ]], [[Hypothyroidism]], [[Iodine deficiency]], [[Iodine excess]], [[Kaplowitz-bodurtha syndrome ]], [[Lymphocytic hypophysitis]], [[Lymphocytic thyroiditis]], [[Lymphomatous thyroiditis ]], [[Multiple endocrine abnormalities ]], [[Panhypopituitarism]], [[Peripheral thyroid gland disorder resistance]], [[Pituitary adenoma]], [[Pituitary apoplexy]], [[Pituitary cancer ]], [[Pituitary dwarfism type 3]], [[Pituitary dysfunction ]], [[Polyendocrinopathy]], [[Polyglandular disorders]], [[Postpartum thyroiditis ]], [[Primary hypothyroidism]], [[Pseudohypoparathyroidism type 1a]], [[Rathke's cleft cyst]], [[Reidel's thyroiditis]], [[Resistance to thyroid hormone ]], [[Retinohepatoendocrinologic syndrome ]], [[Riedel syndrome ]], [[Secondary hypothyroidism]], [[Sheehan syndrome]], [[Silent thyroiditis]], [[Subacute granulomatous thyroiditis]], [[Subacute lymphocytic thyroiditis]], [[Subacute thyroiditis]], [[Subtotal thyroidectomy]], [[Supprative thyroiditis]], [[Thyreostatic therapy]], [[Thyroid dysgenesis ]], [[Thyroid dyshormonogenesis ]], [[Thyroid ectopy]], [[Thyroid hormone resistance ]], [[Thyroid stimulating hormone deficiency]], [[Thyroidectomy]], [[Thyroiditis]], [[Trh deficiency]], [[Tsh deficiency]] | | bgcolor="Beige" | [[Abnormal maternal iodine levels]], [[Acth deficiency]], [[Antithyroid drugs]], [[Apeced syndrome]], [[Autoimmune polyendocrine syndrome type 3]], [[Autoimmune thyroiditis]], [[Brain-lung-thyroid syndrome]], [[Central hypothyroidism]], [[Chronic autoimmune thyroiditis]], [[Combined pituitary hormone deficiency 1 (pou1f1 gene)]], [[Combined pituitary hormone deficiency 2 (prop1 gene)]], [[Combined pituitary hormone deficiency 3 (lhx gene)]], [[Congenital disorder of glycosylation type 1a ]] , [[Congenital disorder of glycosylation type 1h ]] , [[Congenital thyroid dysgenesis]], [[Cretinism athyreotic ]] , [[De quervain thyroiditis]], [[Deficiency of pit1]], [[Dopamine]], [[Empty sella]], [[Escamilla-lisser syndrome ]] , [[Fibrous thyroiditis]], [[Goiter ]] , [[Graves disease ]] , [[Hashimoto's thyroiditis]], [[Hemochromatosis]], [[Hyperthyroidism ]] , [[Hypoadrenocorticism ]] , [[Hypomelia ]] , [[Hypopituitarism]], [[Hypothalamic dysfunction ]] , [[Hypothyroidism]], [[Iodine deficiency]], [[Iodine excess]], [[Kaplowitz-bodurtha syndrome ]] , [[Lymphocytic hypophysitis]], [[Lymphocytic thyroiditis]], [[Lymphomatous thyroiditis ]] , [[Multiple endocrine abnormalities ]] , [[Panhypopituitarism]], [[Peripheral thyroid gland disorder resistance]], [[Pituitary adenoma]], [[Pituitary apoplexy]], [[Pituitary cancer ]] , [[Pituitary dwarfism type 3]], [[Pituitary dysfunction ]] , [[Polyendocrinopathy]], [[Polyglandular disorders]], [[Postpartum thyroiditis ]] , [[Primary hypothyroidism]], [[Pseudohypoparathyroidism type 1a]], [[Rathke's cleft cyst]], [[Reidel's thyroiditis]], [[Resistance to thyroid hormone ]] , [[Retinohepatoendocrinologic syndrome ]] , [[Riedel syndrome ]] , [[Secondary hypothyroidism]], [[Sheehan syndrome]], [[Silent thyroiditis]], [[Subacute granulomatous thyroiditis]], [[Subacute lymphocytic thyroiditis]], [[Subacute thyroiditis]], [[Subtotal thyroidectomy]], [[Supprative thyroiditis]], [[Thyreostatic therapy]], [[Thyroid dysgenesis ]] , [[Thyroid dyshormonogenesis ]] , [[Thyroid ectopy]], [[Thyroid hormone resistance ]] , [[Thyroid stimulating hormone deficiency]], [[Thyroidectomy]], [[Thyroiditis]], [[Trh deficiency]], [[Tsh deficiency]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Environmental''' | | '''Environmental''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Gastroenterologic''' | | '''Gastroenterologic''' | ||
|bgcolor="Beige"| [[Diarrhea]], [[Enteropathy]], [[Retinohepatoendocrinologic syndrome ]] | | bgcolor="Beige" | [[Diarrhea]], [[Enteropathy]], [[Retinohepatoendocrinologic syndrome ]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Genetic''' | | '''Genetic''' | ||
|bgcolor="Beige"| [[17-beta-hydroxysteroid dehydrogenase iii deficiency ]], [[Abnormal maternal iodine levels]], [[Acth deficiency]], [[Alström syndrome]], [[Bamforth syndrome ]], [[Bangstad syndrome ]], [[Cdg syndrome type 1a ]], [[Chromosome 1, 1p36 deletion syndrome ]], [[Chromosome 10, monosomy 10p ]], [[Chromosome 10p deletion syndrome]], [[Chromosome 12 ring syndrome ]], [[Chromosome 15q duplication syndrome ]], [[Chromosome 15q, trisomy ]], [[Chromosome 2 trisomy syndrome ]], [[Chromosome 6, trisomy 6q ]], [[Chromosome 6q duplication syndrome ]], [[Combined pituitary hormone deficiency 1 (pou1f1 gene)]], [[Combined pituitary hormone deficiency 2 (prop1 gene)]], [[Combined pituitary hormone deficiency 3 (lhx gene)]], [[Congenital disorder of glycosylation type 1a ]], [[Congenital disorder of glycosylation type 1h ]], [[Congenital thyroid dysgenesis]], [[Cystinosis]], [[Deficiency of pit1]], [[Digeorge syndrome]], [[Down syndrome]], [[Emanuel syndrome]], [[Ipex syndrome]], [[Johanson-blizzard syndrome ]], [[Kaplowitz-bodurtha syndrome ]], [[Langerhans cell histiocytosis]], [[Monosomy 1p36 ]], [[Mutations ]], [[Ohdo syndrome]], [[Pax8]], [[Pendred's syndrome ]], [[Poems syndrome]], [[Septo-optic dysplasia]], [[Turner syndrome]], [[Velocardiofacial syndrome ]], [[Vilanova-canadeli syndrome ]], [[Wolfram syndrome 2 ]], [[Zadik barak levin syndrome ]] | | bgcolor="Beige" | [[17-beta-hydroxysteroid dehydrogenase iii deficiency ]] , [[Abnormal maternal iodine levels]], [[Acth deficiency]], [[Alström syndrome]], [[Bamforth syndrome ]] , [[Bangstad syndrome ]] , [[Cdg syndrome type 1a ]] , [[Chromosome 1, 1p36 deletion syndrome ]] , [[Chromosome 10, monosomy 10p ]] , [[Chromosome 10p deletion syndrome]], [[Chromosome 12 ring syndrome ]] , [[Chromosome 15q duplication syndrome ]] , [[Chromosome 15q, trisomy ]] , [[Chromosome 2 trisomy syndrome ]] , [[Chromosome 6, trisomy 6q ]] , [[Chromosome 6q duplication syndrome ]] , [[Combined pituitary hormone deficiency 1 (pou1f1 gene)]], [[Combined pituitary hormone deficiency 2 (prop1 gene)]], [[Combined pituitary hormone deficiency 3 (lhx gene)]], [[Congenital disorder of glycosylation type 1a ]] , [[Congenital disorder of glycosylation type 1h ]] , [[Congenital thyroid dysgenesis]], [[Cystinosis]], [[Deficiency of pit1]], [[Digeorge syndrome]], [[Down syndrome]], [[Emanuel syndrome]], [[Ipex syndrome]], [[Johanson-blizzard syndrome ]] , [[Kaplowitz-bodurtha syndrome ]] , [[Langerhans cell histiocytosis]], [[Monosomy 1p36 ]] , [[Mutations ]] , [[Ohdo syndrome]], [[Pax8]], [[Pendred's syndrome ]] , [[Poems syndrome]], [[Septo-optic dysplasia]], [[Turner syndrome]], [[Velocardiofacial syndrome ]] , [[Vilanova-canadeli syndrome ]] , [[Wolfram syndrome 2 ]] , [[Zadik barak levin syndrome ]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Hematologic''' | | '''Hematologic''' | ||
|bgcolor="Beige"| [[Diabetes insipidus]], [[Diabetes mellitus]], [[Hemochromatosis]], [[Hemocyte]], [[Iodine deficiency]], [[Iodine excess]], [[Iron overload ]], [[Isolated tsh deficiency]], [[Maternal antibody]], [[Subarachnoid hemorrhage]] | | bgcolor="Beige" | [[Diabetes insipidus]], [[Diabetes mellitus]], [[Hemochromatosis]], [[Hemocyte]], [[Iodine deficiency]], [[Iodine excess]], [[Iron overload ]] , [[Isolated tsh deficiency]], [[Maternal antibody]], [[Subarachnoid hemorrhage]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Iatrogenic''' | | '''Iatrogenic''' | ||
|bgcolor="Beige"| [[Iatrogenic]], [[Neck radiotherapy]], [[Neck surgery]], [[Radiation therapy]], [[Radioactive iodine therapy]], [[Subtotal thyroidectomy]], [[Supprative thyroiditis]], [[Thyroidectomy]] | | bgcolor="Beige" | [[Iatrogenic]], [[Neck radiotherapy]], [[Neck surgery]], [[Radiation therapy]], [[Radioactive iodine therapy]], [[Subtotal thyroidectomy]], [[Supprative thyroiditis]], [[Thyroidectomy]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Infectious Disease''' | | '''Infectious Disease''' | ||
|bgcolor="Beige"| [[Iodine antenatal infection ]], [[Mycoses]], [[Rathke's cleft cyst]], [[Syphilis]], [[Tuberculosis]] | | bgcolor="Beige" | [[Iodine antenatal infection ]] , [[Mycoses]], [[Rathke's cleft cyst]], [[Syphilis]], [[Tuberculosis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Musculoskeletal/Orthopedic''' | | '''Musculoskeletal/Orthopedic''' | ||
|bgcolor="Beige"| [[Bilateral abductor vocal cord paralysis syndrome ]] | | bgcolor="Beige" | [[Bilateral abductor vocal cord paralysis syndrome ]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Neurologic''' | | '''Neurologic''' | ||
|bgcolor="Beige"| [[Aneurysm of the internal carotid artery]], [[Brain-lung-thyroid syndrome]], [[Craniopharyngioma]], [[Dopamine]], [[Down syndrome]], [[Microcephaly ]], [[Microphthalmia syndromic]], [[Neurosarcoidosis ]], [[Subarachnoid hemorrhage]] | | bgcolor="Beige" | [[Aneurysm of the internal carotid artery]], [[Brain-lung-thyroid syndrome]], [[Craniopharyngioma]], [[Dopamine]], [[Down syndrome]], [[Microcephaly ]] , [[Microphthalmia syndromic]], [[Neurosarcoidosis ]] , [[Subarachnoid hemorrhage]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Nutritional/Metabolic''' | | '''Nutritional/Metabolic''' | ||
|bgcolor="Beige"| [[Diabetes insipidus]], [[Diabetes mellitus]], [[Diarrhea]], [[Obesity ]] | | bgcolor="Beige" | [[Diabetes insipidus]], [[Diabetes mellitus]], [[Diarrhea]], [[Obesity ]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Obstetric/Gynecologic''' | | '''Obstetric/Gynecologic''' | ||
|bgcolor="Beige"| [[Neonatal illness]], [[Sheehan syndrome]] | | bgcolor="Beige" | [[Neonatal illness]], [[Sheehan syndrome]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Oncologic''' | | '''Oncologic''' | ||
|bgcolor="Beige"| [[Craniopharyngioma]], [[Glioma]], [[Hypomelia ]], [[Meningioma]], [[Metastasis]], [[Neoplastic]], [[Pituitary adenoma]], [[Pituitary apoplexy]], [[Pituitary cancer ]] | | bgcolor="Beige" | [[Craniopharyngioma]], [[Glioma]], [[Hypomelia ]] , [[Meningioma]], [[Metastasis]], [[Neoplastic]], [[Pituitary adenoma]], [[Pituitary apoplexy]], [[Pituitary cancer ]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Ophthalmologic''' | | '''Ophthalmologic''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Overdose/Toxicity''' | | '''Overdose/Toxicity''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Psychiatric''' | | '''Psychiatric''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Pulmonary''' | | '''Pulmonary''' | ||
|bgcolor="Beige"| [[Amyloidosis]], [[Tuberculosis]] | | bgcolor="Beige" | [[Amyloidosis]], [[Tuberculosis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Renal/Electrolyte''' | | '''Renal/Electrolyte''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Rheumatology/Immunology/Allergy''' | | '''Rheumatology/Immunology/Allergy''' | ||
|bgcolor="Beige"| [[Amyloidosis]], [[Anti-tsh receptor antibodies]], [[Apeced syndrome]], [[Autoimmune disorders]], [[Autoimmune enteropathy]], [[Autoimmune polyendocrine syndrome type 3]], [[Autoimmune thyroiditis]], [[Chronic autoimmune thyroiditis]], [[Dermatosclerosis]], [[Fibrous thyroiditis]], [[Graves disease ]], [[Immune dysregulation ]], [[Kashin-bek disease ]], [[Langerhans cell histiocytosis]], [[Neurosarcoidosis ]], [[Rheumatoid arthritis]], [[Sarcoidosis]], [[Scleroderma]] | | bgcolor="Beige" | [[Amyloidosis]], [[Anti-tsh receptor antibodies]], [[Apeced syndrome]], [[Autoimmune disorders]], [[Autoimmune enteropathy]], [[Autoimmune polyendocrine syndrome type 3]], [[Autoimmune thyroiditis]], [[Chronic autoimmune thyroiditis]], [[Dermatosclerosis]], [[Fibrous thyroiditis]], [[Graves disease ]] , [[Immune dysregulation ]] , [[Kashin-bek disease ]] , [[Langerhans cell histiocytosis]], [[Neurosarcoidosis ]] , [[Rheumatoid arthritis]], [[Sarcoidosis]], [[Scleroderma]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Sexual''' | | '''Sexual''' | ||
|bgcolor="Beige"| [[Syphilis]] | | bgcolor="Beige" | [[Syphilis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Trauma''' | | '''Trauma''' | ||
|bgcolor="Beige"| [[Injury]] | | bgcolor="Beige" | [[Injury]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Urologic''' | | '''Urologic''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Miscellaneous''' | | '''Miscellaneous''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|} | |} | ||
===Causes in Alphabetical Order=== | ===Causes in Alphabetical Order=== | ||
{{columns-list | {{columns-list| | ||
*[[17-beta-hydroxysteroid dehydrogenase iii deficiency ]] | *[[17-beta-hydroxysteroid dehydrogenase iii deficiency ]] | ||
*[[Abnormal maternal iodine levels]] | *[[Abnormal maternal iodine levels]] |
Latest revision as of 21:22, 10 January 2020
Hypothyroidism Main page |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Vignesh Ponnusamy, M.B.B.S. [2] Luke Rusowicz-Orazem, B.S.
Overview
Causes
The most common cause of hypothyroidism is thyroiditis. Swelling and inflammation damage the thyroid gland's cells.
Causes of this problem include:
- The immune system attacking the thyroid gland
- Viral infections (common cold) or other respiratory infections
- Pregnancy (often called postpartum thyroiditis)
Other causes of hypothyroidism include:
- Certain medicines, such as lithium and amiodarone
- Congenital (birth) defects
- Radiation treatments to the neck or brain to treat different cancers
- Radioactive iodine used to treat an overactive thyroid gland
- Surgical removal of part or all of the thyroid gland
- Sheehan syndrome, a condition that may occur in a woman who bleeds severely during pregnancy or childbirth and causes the destruction of the pituitary gland
- Pituitary tumor or pituitary surgery
Life Threatening Causes
- Aneurysm
- Subarachnoid hemorrhage
- Craniopharyngioma
- Glioma
- Hypomelia
- Meningioma
- Metastasis
- Neoplastic
- Pituitary adenoma
- Pituitary apoplexy
- Pituitary cancer
- Syphilis
Common Causes
- Iodine deficiency
- Hashimoto's thyroiditis
- Thyroid hormone resistance
- Thyroid stimulating hormone deficiency
- Trh deficiency
- Tsh deficiency
Causes by Organ System
Causes in Alphabetical Order
- 17-beta-hydroxysteroid dehydrogenase iii deficiency
- Abnormal maternal iodine levels
- Acth deficiency
- Alström syndrome
- Aminoglutethimide
- Amiodarone
- Amyloidosis
- Aneurysm of the internal carotid artery
- Antithyroid drugs
- Anti-tsh receptor antibodies
- Apeced syndrome
- Atezolizumab
- Autoimmune disorders
- Autoimmune enteropathy
- Autoimmune polyendocrine syndrome type 3
- Autoimmune thyroiditis
- Axitinib
- Bamforth syndrome
- Bangstad syndrome
- Bexarotene
- Bilateral abductor vocal cord paralysis syndrome
- Brain-lung-thyroid syndrome
- Bromide
- Carbimazole
- Catch 22
- Cdg syndrome type 1a
- Central hypothyroidism
- Chromosome 1, 1p36 deletion syndrome
- Chromosome 10, monosomy 10p
- Chromosome 10p deletion syndrome
- Chromosome 12 ring syndrome
- Chromosome 15q duplication syndrome
- Chromosome 15q, trisomy
- Chromosome 2 trisomy syndrome
- Chromosome 6, trisomy 6q
- Chromosome 6q duplication syndrome
- Chronic autoimmune thyroiditis
- Combined pituitary hormone deficiency 1 (pou1f1 gene)
- Combined pituitary hormone deficiency 2 (prop1 gene)
- Combined pituitary hormone deficiency 3 (lhx gene)
- Congenital disorder of glycosylation type 1a
- Congenital disorder of glycosylation type 1h
- Congenital thyroid dysgenesis
- Craniopharyngioma
- Cretinism athyreotic
- Cystinosis
- De quervain thyroiditis
- Deficiency of pit1
- Dermatosclerosis
- Diabetes insipidus
- Diabetes mellitus
- Diarrhea
- Digeorge syndrome
- Dopamine
- Down syndrome
- Ed-in-sol
- Emanuel syndrome
- Empty sella
- Enteropathy
- Escamilla-lisser syndrome
- Ethionamide
- Femiron
- Feosol
- Feostat
- Feratab
- Fer-gen-sol
- Fergon
- Fer-in-sol
- Ferrex
- Fibrous thyroiditis
- Glioma
- Goiter
- Graves disease
- Hashimoto's thyroiditis
- Hemochromatosis
- Hemocyte
- Hyperthyroidism
- Hypoadrenocorticism
- Hypomelia
- Hypopituitarism
- Hypothalamic dysfunction
- Hypothyroidism
- Hytinic
- Iatrogenic
- Icar
- Immune dysregulation
- Injury
- Interferon alfacon-1
- Interferon alpha
- Interferon-alfa
- Interleukin-2
- Iodine 131
- Iodine antenatal infection
- Iodine deficiency
- Iodine excess
- Ipex syndrome
- Ircon
- Iron overload
- Isolated tsh deficiency
- Johanson-blizzard syndrome
- Kaplowitz-bodurtha syndrome
- Kashin-bek disease
- Langerhans cell histiocytosis
- Lithium
- Lymphocytic hypophysitis
- Lymphocytic thyroiditis
- Lymphomatous thyroiditis
- Maternal antibody
- Meningioma
- Metastasis
- Methimazole
- Microcephaly
- Microphthalmia syndromic
- Mitotane
- Monosomy 1p36
- Multiple endocrine abnormalities
- Mutations
- Mycoses
- Neck radiotherapy
- Neck surgery
- Neonatal illness
- Neoplastic
- Nephro-fer
- Neurosarcoidosis
- Neutral lipid storage disease
- Niferex
- Nivolumab
- Nu-iron
- Obesity
- Ohdo syndrome
- Oxcarbazepine
- Panhypopituitarism
- Para-amino salicylic acid
- Pax8
- Peginterferon beta-1a
- Pegylated interferon alfa-2b
- Pembrolizumab
- Pendred's syndrome
- Perchlorate
- Pergolide
- Peripheral thyroid gland disorder resistance
- Phenytoin and levothyroxine interaction
- Pituitary adenoma
- Pituitary apoplexy
- Pituitary cancer
- Pituitary dwarfism type 3
- Pituitary dysfunction
- Poems syndrome
- Polyendocrinopathy
- Polyglandular disorders
- Postpartum thyroiditis
- Potassium iodide
- Pramipexole
- Previous grave's disease
- Primary hypothyroidism
- Propylthiouracil
- Pseudohypoparathyroidism type 1a
- Radiation therapy
- Radioactive iodine therapy
- Rathke's cleft cyst
- Reidel's thyroiditis
- Resistance to thyroid hormone
- Retinohepatoendocrinologic syndrome
- Rheumatoid arthritis
- Riedel syndrome
- Sarcoidosis
- Scleroderma
- Secondary hypothyroidism
- Septo-optic dysplasia
- Sheehan syndrome
- Silent thyroiditis
- Slow-fe
- Sorafenib
- Subacute granulomatous thyroiditis
- Subacute lymphocytic thyroiditis
- Subacute thyroiditis
- Subarachnoid hemorrhage
- Subtotal thyroidectomy
- Supprative thyroiditis
- Syphilis
- Thionamides
- Thyreostatic therapy
- Thyroid and cholestyramine interaction
- Thyroid dysgenesis
- Thyroid dyshormonogenesis
- Thyroid ectopy
- Thyroid hormone resistance
- Thyroid stimulating hormone deficiency
- Thyroidectomy
- Thyroiditis
- Tiagabine
- Tocilizumab
- Tositumomab iodine-131
- Trh deficiency
- Tsh deficiency
- Ttf-1
- Ttf-2
- Tuberculosis
- Turner syndrome
- Tyrosine kinase inhibitors
- Velocardiofacial syndrome
- Vilanova-canadeli syndrome
- Vitron-c
- Wolfram syndrome 2
- Zadik barak levin syndrome