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==Overview==
==Overview==
Rotavirus clinical manifestations usually start to develop two days after the infection. It is more severe in the children more than the adults. Its severity depends on whether it is the first infection or recurrent one. The first infection is more severe. It may be asymptomatic or causes watery diarrhea and in very severe cases it may cause severe dehydration. The children infected by the rotavirus present with high grade fever as well as vomiting.<ref name= "Rotavirus"> CDC https://www.cdc.gov/vaccines/pubs/pinkbook/rota.html#rotavirus Accessed on May 2 , 2017 </ref><ref name="pmid24379214">{{cite journal| author=Parashar UD, Nelson EA, Kang G| title=Diagnosis, management, and prevention of rotavirus gastroenteritis in children. | journal=BMJ | year= 2013 | volume= 347 | issue=  | pages= f7204 | pmid=24379214 | doi=10.1136/bmj.f7204 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24379214  }} </ref>
[[Rotavirus]] clinical manifestations usually start to develop two days after the [[infection]]. It is more severe in the children more than the adults. Its severity depends on whether it is the first [[infection]] or recurrent one. The first infection is more severe. It may be asymptomatic or causes watery [[diarrhea]] and in very severe cases it may cause severe [[dehydration]]. The children infected by the [[rotavirus]] present with high grade [[fever]] as well as [[vomiting]].<ref name= "Rotavirus"> CDC https://www.cdc.gov/vaccines/pubs/pinkbook/rota.html#rotavirus Accessed on May 2 , 2017 </ref><ref name="pmid24379214">{{cite journal| author=Parashar UD, Nelson EA, Kang G| title=Diagnosis, management, and prevention of rotavirus gastroenteritis in children. | journal=BMJ | year= 2013 | volume= 347 | issue=  | pages= f7204 | pmid=24379214 | doi=10.1136/bmj.f7204 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24379214  }} </ref>


==History and symptoms==
==History and symptoms==
Rotavirus infection can be asymptomatic in mild cases. It can also cause watery diarrhea and vomiting which may results in severe dehydration.<ref name="pmid12005086">{{cite journal| author=Staat MA, Azimi PH, Berke T, Roberts N, Bernstein DI, Ward RL et al.| title=Clinical presentations of rotavirus infection among hospitalized children. | journal=Pediatr Infect Dis J | year= 2002 | volume= 21 | issue= 3 | pages= 221-7 | pmid=12005086 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12005086  }} </ref>  
Rotavirus infection can be asymptomatic in mild cases and in the [[neonates]]. In neonates it is mostly asymptomatic due to the [[maternity|maternal]] [[antibodies]].<ref name="pmid19457420">{{cite journal| author=Greenberg HB, Estes MK| title=Rotaviruses: from pathogenesis to vaccination. | journal=Gastroenterology | year= 2009 | volume= 136 | issue= 6 | pages= 1939-51 | pmid=19457420 | doi=10.1053/j.gastro.2009.02.076 | pmc=3690811 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19457420  }} </ref> It can also cause watery [[diarrhea]] and [[vomiting]] which may results in severe [[dehydration]].<ref name="pmid12005086">{{cite journal| author=Staat MA, Azimi PH, Berke T, Roberts N, Bernstein DI, Ward RL et al.| title=Clinical presentations of rotavirus infection among hospitalized children. | journal=Pediatr Infect Dis J | year= 2002 | volume= 21 | issue= 3 | pages= 221-7 | pmid=12005086 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12005086  }} </ref>  


===Common symptoms===  
===Common symptoms===  
*Watery diarrhea
*[[Watery diarrhea]]
*Vomiting  
*[[Vomiting]]
*Abdominal pain
*[[Abdominal pain]]
*Fever
*[[Fever]]


===Less common symptoms===
===Less common symptoms===
In severe cases the following may develop:  
In severe cases the following may develop:  
*Dehydration and its symptoms include the following:<ref name= "Rotavirus"> CDC https://www.cdc.gov/rotavirus/about/symptoms.html Accessed on May 2, 2017 </ref>  
*[[Dehydration]] and its symptoms include the following:<ref name= "Rotavirus"> CDC https://www.cdc.gov/rotavirus/about/symptoms.html Accessed on May 2, 2017 </ref>  
**Decrease in urination
**[[Oliguria|Decrease in urination]]
**Dry mouth and throat
**Dry [[mouth]] and throat
**Feeling dizzy when standing up
**Feeling [[dizzy]] when standing up
**In the dehydrated children, the child cries with few or no tears and be unusually sleepy or fussy
**In the dehydrated children, the child cries with few or no tears and be unusually sleepy or fussy
*Seizures as the rotavirus can affect the central nervous system
*[[Seizures]] as the [[rotavirus]] can affect the [[central nervous system]].


==References==
==References==
{{reflist|2}}
{{reflist|2}}


[[Category:Disease]]
[[Category:Emergency mdicine]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Infectious disease]]
[[Category:Disease]]
[[Category:Gastroenterology]]
[[Category:Pediatrics]]

Latest revision as of 00:03, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Rotavirus clinical manifestations usually start to develop two days after the infection. It is more severe in the children more than the adults. Its severity depends on whether it is the first infection or recurrent one. The first infection is more severe. It may be asymptomatic or causes watery diarrhea and in very severe cases it may cause severe dehydration. The children infected by the rotavirus present with high grade fever as well as vomiting.[1][2]

History and symptoms

Rotavirus infection can be asymptomatic in mild cases and in the neonates. In neonates it is mostly asymptomatic due to the maternal antibodies.[3] It can also cause watery diarrhea and vomiting which may results in severe dehydration.[4]

Common symptoms

Less common symptoms

In severe cases the following may develop:

References

  1. 1.0 1.1 CDC https://www.cdc.gov/vaccines/pubs/pinkbook/rota.html#rotavirus Accessed on May 2 , 2017
  2. Parashar UD, Nelson EA, Kang G (2013). "Diagnosis, management, and prevention of rotavirus gastroenteritis in children". BMJ. 347: f7204. doi:10.1136/bmj.f7204. PMID 24379214.
  3. Greenberg HB, Estes MK (2009). "Rotaviruses: from pathogenesis to vaccination". Gastroenterology. 136 (6): 1939–51. doi:10.1053/j.gastro.2009.02.076. PMC 3690811. PMID 19457420.
  4. Staat MA, Azimi PH, Berke T, Roberts N, Bernstein DI, Ward RL; et al. (2002). "Clinical presentations of rotavirus infection among hospitalized children". Pediatr Infect Dis J. 21 (3): 221–7. PMID 12005086.