Roseola historical perspective: Difference between revisions
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==Overview== | ==Overview== | ||
For the first time, Zahorsky of St. Louis in 1910 described a febrile [[exanthem]] occurring in infants which he termed roseola. Human herpes virus 6 was first identified in 1986. | |||
==Historical | ==Historical Perspective== | ||
*In 1986, | *For the first time, Zahorsky of St. Louis in 1910 described a febrile [[exanthem]] occurring in infants which he termed roseola. | ||
*In 1986, Human herpes virus 6 (HHV6), the main causative agent of roseola disease was first isolated from patients who were diagnosed with [[HIV AIDS]] or a [[Lymphoproliferative disorders|lymphoproliferative disorder]] from the peripheral blood [[leukocytes]]. <ref name="pmid2876520">{{cite journal| author=Salahuddin SZ, Ablashi DV, Markham PD, Josephs SF, Sturzenegger S, Kaplan M et al.| title=Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders. | journal=Science | year= 1986 | volume= 234 | issue= 4776 | pages= 596-601 | pmid=2876520 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2876520 }} </ref> | |||
* The two different variants of HHV 6 discovered by Frenkel, Ablashi and Aubin are variant A and Variant B HHV 6 strains.<ref name="pmid1648234">{{cite journal| author=Schirmer EC, Wyatt LS, Yamanishi K, Rodriguez WJ, Frenkel N| title=Differentiation between two distinct classes of viruses now classified as human herpesvirus 6. | journal=Proc Natl Acad Sci U S A | year= 1991 | volume= 88 | issue= 13 | pages= 5922-6 | pmid=1648234 | doi= | pmc=51990 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1648234 }} </ref><ref name="pmid1653487">{{cite journal| author=Ablashi DV, Balachandran N, Josephs SF, Hung CL, Krueger GR, Kramarsky B et al.| title=Genomic polymorphism, growth properties, and immunologic variations in human herpesvirus-6 isolates. | journal=Virology | year= 1991 | volume= 184 | issue= 2 | pages= 545-52 | pmid=1653487 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1653487 }} </ref><ref name="pmid1848868">{{cite journal| author=Aubin JT, Collandre H, Candotti D, Ingrand D, Rouzioux C, Burgard M et al.| title=Several groups among human herpesvirus 6 strains can be distinguished by Southern blotting and polymerase chain reaction. | journal=J Clin Microbiol | year= 1991 | volume= 29 | issue= 2 | pages= 367-72 | pmid=1848868 | doi= | pmc=269769 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1848868 }} </ref> | |||
*HHV 6A has been found to be more associated with the development of roseola. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Emergency mdicine]] | |||
[[Category:Disease]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Infectious disease]] | |||
[[Category:Neurology]] | |||
[[Category:Pediatrics]] | |||
[[Category:Dermatology]] | |||
Latest revision as of 00:03, 30 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omodamola Aje B.Sc, M.D. [2]
Overview
For the first time, Zahorsky of St. Louis in 1910 described a febrile exanthem occurring in infants which he termed roseola. Human herpes virus 6 was first identified in 1986.
Historical Perspective
- For the first time, Zahorsky of St. Louis in 1910 described a febrile exanthem occurring in infants which he termed roseola.
- In 1986, Human herpes virus 6 (HHV6), the main causative agent of roseola disease was first isolated from patients who were diagnosed with HIV AIDS or a lymphoproliferative disorder from the peripheral blood leukocytes. [1]
- The two different variants of HHV 6 discovered by Frenkel, Ablashi and Aubin are variant A and Variant B HHV 6 strains.[2][3][4]
- HHV 6A has been found to be more associated with the development of roseola.
References
- ↑ Salahuddin SZ, Ablashi DV, Markham PD, Josephs SF, Sturzenegger S, Kaplan M; et al. (1986). "Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders". Science. 234 (4776): 596–601. PMID 2876520.
- ↑ Schirmer EC, Wyatt LS, Yamanishi K, Rodriguez WJ, Frenkel N (1991). "Differentiation between two distinct classes of viruses now classified as human herpesvirus 6". Proc Natl Acad Sci U S A. 88 (13): 5922–6. PMC 51990. PMID 1648234.
- ↑ Ablashi DV, Balachandran N, Josephs SF, Hung CL, Krueger GR, Kramarsky B; et al. (1991). "Genomic polymorphism, growth properties, and immunologic variations in human herpesvirus-6 isolates". Virology. 184 (2): 545–52. PMID 1653487.
- ↑ Aubin JT, Collandre H, Candotti D, Ingrand D, Rouzioux C, Burgard M; et al. (1991). "Several groups among human herpesvirus 6 strains can be distinguished by Southern blotting and polymerase chain reaction". J Clin Microbiol. 29 (2): 367–72. PMC 269769. PMID 1848868.