Diverticulitis risk factors: Difference between revisions

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==Overview==
==Overview==
Risk factors in the development of diverticulitis include advanced age, chronic [[constipation]], [[connective tissue disease]]s (such as [[Marfan syndrome]] or [[Ehlers Danlos syndrome]]), low dietary fiber intake, high intake of fat and red meat, and obesity. There are risk factors for the disease recurrence as well. These factors include multiple diverticula, intraperitoneal abscess, family history of diverticulitis, and great portion of the colon involved in the disease.
The most potent [[risk factors]] for disease recurrence include multiple [[Diverticulum|diverticula]], [[intraperitoneal]] [[abscess]], [[family history]] of diverticulitis, and having a large portion of the [[colon]] involved in the disease.


==Risk Factors==
==Risk Factors==
===Risk factors of diverticulosis and diverticulitis===
===Risk factors for the recurrence of diverticulitis===
Risk factors in the development of diverticulosis and diverticulitis include the following:<ref name="pmid18996378">{{cite journal |vauthors=Strate LL, Liu YL, Aldoori WH, Syngal S, Giovannucci EL |title=Obesity increases the risks of diverticulitis and diverticular bleeding |journal=Gastroenterology |volume=136 |issue=1 |pages=115–122.e1 |year=2009 |pmid=18996378 |pmc=2643271 |doi=10.1053/j.gastro.2008.09.025 |url=}}</ref>
Recurrence of diverticulitis has been reported to occur in 20% of patients with previous episodes of diverticulitis.<ref name="pmid27241190">{{cite journal| author=Peery AF| title=Recent Advances in Diverticular Disease. | journal=Curr Gastroenterol Rep | year= 2016 | volume= 18 | issue= 7 | pages= 37 | pmid=27241190 | doi=10.1007/s11894-016-0513-1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27241190  }} </ref> [[Risk factors]] for diverticulitis include the following:<ref name="pmid24980689">{{cite journal| author=Park HC, Kim BS, Lee K, Kim MJ, Lee BH| title=Risk factors for recurrence of right colonic uncomplicated diverticulitis after first attack. | journal=Int J Colorectal Dis | year= 2014 | volume= 29 | issue= 10 | pages= 1217-22 | pmid=24980689 | doi=10.1007/s00384-014-1941-8 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24980689  }} </ref><ref name="pmid21304297">{{cite journal| author=Hall JF, Roberts PL, Ricciardi R, Read T, Scheirey C, Wald C et al.| title=Long-term follow-up after an initial episode of diverticulitis: what are the predictors of recurrence? | journal=Dis Colon Rectum | year= 2011 | volume= 54 | issue= 3 | pages= 283-8 | pmid=21304297 | doi=10.1007/DCR.0b013e3182028576 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21304297  }} </ref>
*Advanced age
*[[Diverticulosis]] itself is a risk factor for recurrence  
*Chronic [[constipation]]
*[[Diverticulum|Multiple diverticula]]
*Smoking
*[[Intraperitoneal]] diverticulitis  
*Connective tissue disorders
*Presence of [[retroperitoneal]] [[abscesses]]
:*[[Marfan syndrome]]
*[[Family history]] of diverticulitis  
:*[[Ehlers Danlos syndrome]]
*Having a large portion of [[infected]] [[colon]]
*Low fiber diet
*[[C-reactive protein (CRP)|C-reactive protein]] level more than 240 mg/L<ref name="pmid26649154">{{cite journal| author=Buchs NC, Mortensen NJ, Ris F, Morel P, Gervaz P| title=Natural history of uncomplicated sigmoid diverticulitis. | journal=World J Gastrointest Surg | year= 2015 | volume= 7 | issue= 11 | pages= 313-8 | pmid=26649154 | doi=10.4240/wjgs.v7.i11.313 | pmc=4663385 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26649154  }} </ref>
:*The role of fiber in the development of diverticulitis remains unclear. Although classically low fiber diet has been associated with development of diverticulosis, results from newer studies are conflicting.<ref name="pmid23891924">{{cite journal |vauthors=Peery AF, Sandler RS, Ahnen DJ, Galanko JA, Holm AN, Shaukat A, Mott LA, Barry EL, Fried DA, Baron JA |title=Constipation and a low-fiber diet are not associated with diverticulosis |journal=Clin. Gastroenterol. Hepatol. |volume=11 |issue=12 |pages=1622–7 |year=2013 |pmid=23891924 |pmc=3840096 |doi=10.1016/j.cgh.2013.06.033 |url=}}</ref> However, dietary fiber and a vegetarian diet may reduce the incidence of symptomatic diverticular disease by decreasing intestinal inflammation and altering the intestinal microbiota.<ref name="pmid7942584">{{cite journal |vauthors=Aldoori WH, Giovannucci EL, Rimm EB, Wing AL, Trichopoulos DV, Willett WC |title=A prospective study of diet and the risk of symptomatic diverticular disease in men |journal=Am. J. Clin. Nutr. |volume=60 |issue=5 |pages=757–64 |year=1994 |pmid=7942584 |doi= |url=}}</ref><ref name="pmid4930390">{{cite journal| author=Painter NS, Burkitt DP| title=Diverticular disease of the colon: a deficiency disease of Western civilization. | journal=Br Med J | year= 1971 | volume= 2 | issue= 5759 | pages= 450-4 | pmid=4930390 | doi= | pmc=PMC1796198 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4930390  }} </ref>
*High fiber and red meat diet
:*The risk of diverticulosis may be significantly increased with diets that are high in total fat or red meat compared with fat and red meat-rich diets.<ref name="pmid7942584">{{cite journal |vauthors=Aldoori WH, Giovannucci EL, Rimm EB, Wing AL, Trichopoulos DV, Willett WC |title=A prospective study of diet and the risk of symptomatic diverticular disease in men |journal=Am. J. Clin. Nutr. |volume=60 |issue=5 |pages=757–64 |year=1994 |pmid=7942584 |doi= |url=}}</ref>
*Obesity
 
===Risk factors of diverticulitis recurrence===
Recurrence of diverticulitis has been reported to occur in 20% of patients with previous episodes of diverticulitis.<ref name="pmid27241190">{{cite journal| author=Peery AF| title=Recent Advances in Diverticular Disease. | journal=Curr Gastroenterol Rep | year= 2016 | volume= 18 | issue= 7 | pages= 37 | pmid=27241190 | doi=10.1007/s11894-016-0513-1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27241190  }} </ref>Risk factors for diverticulitis include the following:<ref name="pmid24980689">{{cite journal| author=Park HC, Kim BS, Lee K, Kim MJ, Lee BH| title=Risk factors for recurrence of right colonic uncomplicated diverticulitis after first attack. | journal=Int J Colorectal Dis | year= 2014 | volume= 29 | issue= 10 | pages= 1217-22 | pmid=24980689 | doi=10.1007/s00384-014-1941-8 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24980689  }} </ref><ref name="pmid21304297">{{cite journal| author=Hall JF, Roberts PL, Ricciardi R, Read T, Scheirey C, Wald C et al.| title=Long-term follow-up after an initial episode of diverticulitis: what are the predictors of recurrence? | journal=Dis Colon Rectum | year= 2011 | volume= 54 | issue= 3 | pages= 283-8 | pmid=21304297 | doi=10.1007/DCR.0b013e3182028576 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21304297  }} </ref>
*Diverticulosis itself is a risk factor for recurrence  
*Multiple diverticula  
*Intraperitoneal diverticulitis  
*Presence of retroperitoneal abscesses increase the risk of disease diverticulitis.
*Patients with family history of diverticulitis.
*Patients who have a big portion of the infected colon.


==References==
==References==
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{{Reflist|2}}
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

The most potent risk factors for disease recurrence include multiple diverticulaintraperitoneal abscess, family history of diverticulitis, and having a large portion of the colon involved in the disease.

Risk Factors

Risk factors for the recurrence of diverticulitis

Recurrence of diverticulitis has been reported to occur in 20% of patients with previous episodes of diverticulitis.[1] Risk factors for diverticulitis include the following:[2][3]

References

  1. Peery AF (2016). "Recent Advances in Diverticular Disease". Curr Gastroenterol Rep. 18 (7): 37. doi:10.1007/s11894-016-0513-1. PMID 27241190.
  2. Park HC, Kim BS, Lee K, Kim MJ, Lee BH (2014). "Risk factors for recurrence of right colonic uncomplicated diverticulitis after first attack". Int J Colorectal Dis. 29 (10): 1217–22. doi:10.1007/s00384-014-1941-8. PMID 24980689.
  3. Hall JF, Roberts PL, Ricciardi R, Read T, Scheirey C, Wald C; et al. (2011). "Long-term follow-up after an initial episode of diverticulitis: what are the predictors of recurrence?". Dis Colon Rectum. 54 (3): 283–8. doi:10.1007/DCR.0b013e3182028576. PMID 21304297.
  4. Buchs NC, Mortensen NJ, Ris F, Morel P, Gervaz P (2015). "Natural history of uncomplicated sigmoid diverticulitis". World J Gastrointest Surg. 7 (11): 313–8. doi:10.4240/wjgs.v7.i11.313. PMC 4663385. PMID 26649154.

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