Chickenpox physical examination: Difference between revisions

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Latest revision as of 20:53, 29 July 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S [2]

Overview

The diagnosis of varicella is primarily clinical. Skin lesions on physical examination include pruritic macules on the back, chest, face, abdomen and extremities. Skin lesions progress to papules and heal by crusting. The other common skin lesions include papules, vesicles, pustules and crusts.

Physical Examination

Appearance of the Patient

The patient appears weak and tired with rashes spread over the scalp, face, trunk, and limbs. The intense pruritis triggers recurrent urges to scratch.

Vitals

Low-grade fever
Tachycardia^[1]

Skin

Skin lesions on physical examination include:

Pruritic macules on the back, chest, face, abdomen and extremities.
Skin lesions progress to papules and heal by crusting. Other common skin lesions include:
- Papules
- Vesicles
- Pustules
- Crusts

HEENT

Lungs

Normal breath sounds are heard.

Abdomen

The abdomen will not be tender and there is no organomegaly.

Heart

Normal S1 and S2 are heard.
Ventricular fibrillation presumed to be secondary to myocarditis has been observed in some of the adult population. ^[1]

CNS

The neurological examination may be normal with no focal neurological deficits.
CNS may show the following findings:

Meningitis
Meningoencephalitis
Vasculopathy

Gallery

Chickenpox lesions on the skin of this patient's left breast and arm on day 6 of the illness. From Public Health Image Library (PHIL). ^[2]
Chickenpox lesions on the skin of this patient's back and buttocks at day 6 of the illness. From Public Health Image Library (PHIL). ^[2]
Chickenpox lesions on the skin of this patient's breasts, arms, and torso at day 6 of the illness. From Public Health Image Library (PHIL). ^[2]
Patient with cervical skin lesions caused by chickenpox. From Public Health Image Library (PHIL). ^[2]
4-month old infant with skin lesions on his brow ridge due to chickenpox. From Public Health Image Library (PHIL). ^[2]
Patient had presented with chickenpox demonstrating the typical rash on day eight. From Public Health Image Library (PHIL). ^[2]
Patient developed palatal mucosal lesions due to chickenpox. From Public Health Image Library (PHIL). ^[2]
Vaccine recipient developed a secondary herpes infection adjacent to the vaccination site. From Public Health Image Library (PHIL). ^[2]
Pustulovesicular rash represents a generalized herpes outbreak due to the Varicella-zoster virus (VZV) pathogen. From Public Health Image Library (PHIL). ^[2]
Case of chickenpox. From Public Health Image Library (PHIL). ^[2]
Case of chickenpox. From Public Health Image Library (PHIL). ^[2]
Case of chickenpox. From Public Health Image Library (PHIL). ^[2]
Chickenpox lesions on a patient’s back, which were displaying the characteristic “cropping” distribution, or manifesting themselves in clusters. From Public Health Image Library (PHIL). ^[2]
Posterior view of a hospitalized man's neck, back and shoulders, who’d been assigned a bed in a smallpox ward, due to an initially misdiagnosed illness, which turned out to be chickenpox. From Public Health Image Library (PHIL). ^[2]
View of a patient’s thighs and upper legs, who’d been diagnosed with chickenpox. From Public Health Image Library (PHIL). ^[2]
Pathologic changes seen on the surface of the right unilateral side of this elderly male patient’s tongue and chin, represent a herpes outbreak due to the Varicella-zoster virus (VZV) pathogen. From Public Health Image Library (PHIL). ^[2]
Viewed from above, this image depicts a smallpox scab (left), and chickenpox scab (right) as a demonstration in comparative morphology. From Public Health Image Library (PHIL). ^[2]
Close-up of a maculopapular rash that was diagnosed as a crop of chickenpox lesions. From Public Health Image Library (PHIL). ^[2]
Lateral view of a 4 month-old infant’s face with a single varicella-zoster, otherwise known as chickenpox. From Public Health Image Library (PHIL). ^[2]
This anteroposterior (AP) radiograph revealed bilateral pulmonary infiltrates throughout the entirety of each lung field in the case of a child with leukemia, as well as chickenpox pneumonia. From Public Health Image Library (PHIL). ^[2]
Image depicts three mounted chickenpox scabs seen from the side revealing the superficiality of these scabs when morphologically compared to a smallpox scab. From Public Health Image Library (PHIL). ^[2]
Volar surface of a patient’s left forearm, including the palmar surface of the left hand upon which you’ll note classic maculopapular rash of chickenpox. From Public Health Image Library (PHIL). ^[2]
Right lateral surface of a patient’s right lower leg and foot with classic maculopapular rash of chickenpox. From Public Health Image Library (PHIL). ^[2]
Right lateral surface of a patient’s right lower leg and foot with classic maculopapular rash of chickenpox. From Public Health Image Library (PHIL). ^[2]
Back of boy with chickenpox. From Public Health Image Library (PHIL). ^[2]
Varicella From Public Health Image Library (PHIL). ^[2]
Varicella From Public Health Image Library (PHIL). ^[2]
Varicella From Public Health Image Library (PHIL). ^[2]
Varicella From Public Health Image Library (PHIL). ^[2]
Varicella From Public Health Image Library (PHIL). ^[2]
Varicella From Public Health Image Library (PHIL). ^[2]
Varicella From Public Health Image Library (PHIL). ^[2]
Varicella From Public Health Image Library (PHIL). ^[2]
Vasculitis leukocytoclasia. From Public Health Image Library (PHIL). ^[2]
Vasculitis leukocytoclasia. From Public Health Image Library (PHIL). ^[2]
Vasculitis leukocytoclasia. From Public Health Image Library (PHIL). ^[2]
Vasculitis leukocytoclasia. From Public Health Image Library (PHIL). ^[2]
Vasculitis leukocytoclasia. From Public Health Image Library (PHIL). ^[2]

Unvaccinated Individuals

Girl with a secondary skin infection due to chickenpox.
Chickenpox in an unvaccinated child.
Chickenpox in an unvaccinated adult.
Chickenpox in unvaccinated adult.
Chickenpox in unvaccinated child.

Vaccinated Individuals

Image of Breakthrough Chickenpox: Back of child with breakthrough varicella.
Image of Breakthrough Chickenpox: Back of child with breakthrough varicella.
The skin lesions of breakthrough varicella can be macular rather than vesicular. They are rarely bullous or hemorrhagic, and residual scarring is less common.
Breakthrough varicella on the abdomen of a vaccinated child.
Breakthrough varicella on the back of a vaccinated child.

References

↑ ^1.0 ^1.1 Schraufnagel DE, Becker RP, Balaan M, Schmid A, Claypool W (1989). "Silver staining of Pneumocystis carinii in the rat's lung". J Infect. 18 (1): 39–44. PMID 2464648.
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 ^2.17 ^2.18 ^2.19 ^2.20 ^2.21 ^2.22 ^2.23 ^2.24 ^2.25 ^2.26 ^2.27 ^2.28 ^2.29 ^2.30 ^2.31 ^2.32 ^2.33 ^2.34 ^2.35 ^2.36 ^2.37 "Public Health Image Library (PHIL)".

Template:WikiDoc Sources

[pmid2464648-1] 1.0 ^1.1 Schraufnagel DE, Becker RP, Balaan M, Schmid A, Claypool W (1989). "Silver staining of Pneumocystis carinii in the rat's lung". J Infect. 18 (1): 39–44. PMID 2464648.

[PHIL-2] 2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 ^2.17 ^2.18 ^2.19 ^2.20 ^2.21 ^2.22 ^2.23 ^2.24 ^2.25 ^2.26 ^2.27 ^2.28 ^2.29 ^2.30 ^2.31 ^2.32 ^2.33 ^2.34 ^2.35 ^2.36 ^2.37 "Public Health Image Library (PHIL)".

[1]

[2]

@@ Line 1: / Line 1: @@
 __NOTOC__
-{{CMG}}
+{{CMG}};{{AE}} {{ARK}}
-{{MJM}}
 {{Chickenpox}}
 ==Overview==
-The diagnosis of varicella is primarily clinical. In a non-immunized individual with the appropriate appearing rash occurring in "crops", no further investigation would normally be undertaken. For further investigation, examination of the fluid within the vesicles, or by testing blood for evidence of an acute immunologic response. Vesicle fluid can be examined with a Tsanck smear, or better with examination for [[direct fluorescent antibody]]. The fluid can also be "cultured", whereby attempts are made to grow the virus from a fluid sample. Blood tests can be used to identify a response to acute infection ([[IgM]]) or previous infection and subsequent immunity ([[IgE]]).<ref>McPherson & Pincus: Henry's Clinical Diagnosis and Management by Laboratory Methods, 21st ed., 2007, Chapter 54.
+The diagnosis of [[Chickenpox|varicella]] is primarily [[clinical]]. [[Skin]] lesions on physical examination include [[Pruritic disorders|pruritic]] [[macules]] on the [[back]], [[chest]], [[face]], [[abdomen]] and [[extremities]]. [[Skin]] lesions progress to [[papules]] and [[Healing|heal]] by crusting. The other common [[skin]] lesions include [[papules]], [[vesicles]], [[pustules]] and crusts.
-</ref>.
-Prenatal diagnosis of foetal varicella infection can be performed using [[ultrasound]], though a delay of 5 weeks following primary maternal infection is advised. A [[polymerase chain reaction|PCR]] (DNA) test of the mother's [[amniotic fluid]] can also be performed, though the risk of [[spontaneous abortion]] due to the [[amniocentesis]] procedure is higher than the risk of the baby developing foetal varicella syndrome.
 ==Physical Examination==
-* Differentiation by appearance of the patient.
+===Appearance of the Patient===
+*The patient appears weak and [[tired]] with [[Rash|rashes]] spread over the [[scalp]], [[face]], [[trunk]], and [[limbs]]. The intense [[pruritis]] triggers recurrent urges to scratch.
-====Chickenpox in Unvaccinated People====
+===Vitals===
-* The rash is generalized and [[Itch|pruritic]] (itchy). It progresses rapidly from [[macules]] to [[papules]] to [[vesicular lesions]] before crusting. The rash usually appears first on the head, chest, and back then spreads to the rest of the body. The lesions are usually most concentrated on the chest and back.
+*Low-grade [[fever]]
+*[[Tachycardia]]<ref name="pmid2464648">{{cite journal| author=Schraufnagel DE, Becker RP, Balaan M, Schmid A, Claypool W| title=Silver staining of Pneumocystis carinii in the rat's lung. | journal=J Infect | year= 1989 | volume= 18 | issue= 1 | pages= 39-44 | pmid=2464648 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2464648  }} </ref>
-* In healthy children, varicella is generally mild, with an itchy rash, [[malaise]], and temperature up to 102°F for 2 to 3 days. Adults are at risk for more severe disease and have a higher incidence of complications. Recovery from primary varicella infection usually provides immunity for life. In otherwise healthy people, a second occurrence of varicella is uncommon and usually occurs in people who are [[immunocompromised]]. As with other viral infections, re-exposure to natural (wild-type) varicella may lead to re-infection that boosts antibody] [[titers]] without causing illness or detectable [[viremia]].
+===Skin===
+[[Skin]] lesions on physical examination include:
+*[[Pruritus|Pruritic]] [[macules]] on the [[back]], [[chest]], [[face]], [[abdomen]] and [[extremities]].
+*[[Skin]] lesions progress to [[Papule|papules]] and [[Healing|heal]] by crusting. Other common [[skin]] lesions include:
+**[[Papules]]
+**[[Vesicles]]
+**[[Pustules]]
+**Crusts
-====Chickenpox in Vaccinated People====
+===HEENT===
-* Chickenpox in people who are vaccinated is referred to as breakthrough varicella. Breakthrough varicella is infection with wild-type VZV occurring in a vaccinated person more than 42 days after varicella vaccination. Breakthrough varicella is usually mild. Patients typically are [[afebrile]] or have low fever and develop fewer than 50 skin lesions. They usually have a shorter illness compared to unvaccinated people who get varicella. The rash is more likely to be predominantly [[maculopapular]] rather than [[Vesicular dermatitis|vesicular]]. However, 25%-30% of persons vaccinated with 1 dose with breakthrough varicella have clinical features typical of varicella in unvaccinated people.
+*[[Cervical lymph nodes]]
+*[[Pallor]]
+*[[Skin lesions]]
+*[[Oral ulcers]]
-* Since the clinical features of breakthrough varicella are often mild, it can be difficult to make a diagnosis on clinical presentation alone. Laboratory testing is increasingly important for confirming varicella and appropriately managing cases and their contacts. There is limited information about breakthrough varicella in persons who have received two doses of varicella vaccine, though it appears to occur less frequently among people vaccinated with two doses of varicella vaccine compared to persons who have received a single dose of varicella vaccine.
+===Lungs===
+Normal [[breath sounds]] are heard.
+===Abdomen===
+The abdomen will not be [[Tenderness (medicine)|tender]] and there is no [[organomegaly]].
+===Heart===
+*Normal [[S1]] and [[S2]] are heard.
+*[[Ventricular fibrillation]] presumed to be secondary to [[myocarditis]] has been observed in some of the adult population. <ref name="pmid2464648">{{cite journal| author=Schraufnagel DE, Becker RP, Balaan M, Schmid A, Claypool W| title=Silver staining of Pneumocystis carinii in the rat's lung. | journal=J Infect | year= 1989 | volume= 18 | issue= 1 | pages= 39-44 | pmid=2464648 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2464648  }} </ref>
+===CNS===
+*The [[neurological examination]] may be normal with no focal neurological deficits.
+*CNS may show the following findings:
+:* Meningitis
+:* Meningoencephalitis
+:* Vasculopathy
 ==Gallery==
@@ Line 101: / Line 125: @@
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