Hypogonadism history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The most common symptoms of hypogonadism in males include [[delayed puberty]] and loss of [[Sexual characteristics|sexual characters]] as voice deepening and [[hair]] growth. Common symptoms include also [[erectile dysfunction]], small [[testes]], [[loss of libido]] and [[sweating]]. Common symptoms in females include no [[breast enlargement]] and no [[pubic hair]]. Less common symptoms include a [[headache]], [[visual impairment]], [[galactorrhea]], and [[anorexia nervosa]]. | |||
==History and symptoms== | ==History and symptoms== | ||
History is important in diagnosis of hypogonadism | History is important in the diagnosis of hypogonadism. The onset of the symptoms and previous [[Congenital anomalies|congenital gonadal anomalies]] should be known. | ||
*For both males and females: | *For both males and females: | ||
**History is important to know if there was any gonadal abnormality since birth or not. The onset of puberty should also be known. | **History is important to know if there was any gonadal abnormality since birth or not. The onset of [[puberty]] should also be known. | ||
** | **The family history of delay of growth and development increases the probability of [[Gonadotropins|gonadotropin hormones]] deficiency and hypogonadism. | ||
*For males: | *For males: | ||
**History of any causes of testicular failure as radiation to testes, chemotherapy or drugs decreasing testosterone secretion. | **History of any causes of [[testicular]] failure as radiation to [[testes]], [[chemotherapy]] or [[drugs]] decreasing [[testosterone]] secretion. | ||
*For females: | *For females: | ||
**Menstrual history is important and the date of menarche. | **[[Menstrual]] history is important and the date of [[menarche]]. | ||
**History of increased androgen secretion as | **History of increased [[androgen]] secretion as [[acne]] and [[hirsutism]]. | ||
===Common symptoms in males=== | ===Common symptoms in males=== | ||
Symptoms of hypogonadism | Symptoms of hypogonadism depend on the onset of the disease whether before puberty or after. The common symptoms of hypogonadism in are listed in the following table:<ref name="pmid27343020">{{cite journal| author=Khera M, Broderick GA, Carson CC, Dobs AS, Faraday MM, Goldstein I et al.| title=Adult-Onset Hypogonadism. | journal=Mayo Clin Proc | year= 2016 | volume= 91 | issue= 7 | pages= 908-26 | pmid=27343020 | doi=10.1016/j.mayocp.2016.04.022 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27343020 }} </ref><ref name="pmid24119423">{{cite journal| author=Basaria S| title=Male hypogonadism. | journal=Lancet | year= 2014 | volume= 383 | issue= 9924 | pages= 1250-63 | pmid=24119423 | doi=10.1016/S0140-6736(13)61126-5 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24119423 }} </ref><ref name="pmid20525905">{{cite journal| author=Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS et al.| title=Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. | journal=J Clin Endocrinol Metab | year= 2010 | volume= 95 | issue= 6 | pages= 2536-59 | pmid=20525905 | doi=10.1210/jc.2009-2354 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20525905 }} </ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
!Pre-pubertal | !Pre-pubertal | ||
| Line 25: | Line 27: | ||
* No beard | * No beard | ||
* Failure of voice deepening | * Failure of voice deepening | ||
* Small testes | * Small or absent [[testes]] | ||
* No muscle mass gaining | * [[Muscle wasting|No muscle mass gaining]] | ||
* [[Micropenis]] | |||
* [[Anosmia|Loss of smelling sense]] (In cases of [[Kallmann syndrome]]) | |||
| | | | ||
* Decrease of libido | * Decrease of [[libido]] | ||
* Decreased erections | * Decreased [[Erection|erections]] | ||
* Erectile dysfunction | * [[Erectile dysfunction]] | ||
* Decreased size of testes | * Decreased size of [[testes]] | ||
* Sweating | * [[Sweating]] | ||
* Breast enlargement | * [[Breast enlargement]] | ||
* Muscle loss and decreased bone density | * Muscle loss and decreased [[bone density]] | ||
* Infertility | * [[Infertility]] | ||
* Loss of body hair | * Loss of [[body hair]] | ||
|} | |} | ||
: | === Common symptoms in female: === | ||
* Delayed puberty and loss of the [[secondary sexual characteristics]]: | |||
** No [[breast]] development | |||
** No [[pubic hair]] | |||
===Less common symptoms=== | |||
*[[Headaches]] | |||
*[[Visual loss]] | |||
*[[Galactorrhea]] | |||
*[[Anorexia nervosa]] | |||
*[[Fatigue]] and [[weakness]] | |||
*[[Fatigue|Loss of energy]] | |||
*[[Depression]] | |||
*Sleeping disturbances | |||
*Decreased work performance | |||
==References== | ==References== | ||
Latest revision as of 19:25, 3 October 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
The most common symptoms of hypogonadism in males include delayed puberty and loss of sexual characters as voice deepening and hair growth. Common symptoms include also erectile dysfunction, small testes, loss of libido and sweating. Common symptoms in females include no breast enlargement and no pubic hair. Less common symptoms include a headache, visual impairment, galactorrhea, and anorexia nervosa.
History and symptoms
History is important in the diagnosis of hypogonadism. The onset of the symptoms and previous congenital gonadal anomalies should be known.
- For both males and females:
- History is important to know if there was any gonadal abnormality since birth or not. The onset of puberty should also be known.
- The family history of delay of growth and development increases the probability of gonadotropin hormones deficiency and hypogonadism.
- For males:
- History of any causes of testicular failure as radiation to testes, chemotherapy or drugs decreasing testosterone secretion.
- For females:
Common symptoms in males
Symptoms of hypogonadism depend on the onset of the disease whether before puberty or after. The common symptoms of hypogonadism in are listed in the following table:[1][2][3]
| Pre-pubertal | Post-pubertal (Adult) |
|---|---|
Delayed puberty and loss of sexual characters:
|
|
Common symptoms in female:
- Delayed puberty and loss of the secondary sexual characteristics:
- No breast development
- No pubic hair
Less common symptoms
- Headaches
- Visual loss
- Galactorrhea
- Anorexia nervosa
- Fatigue and weakness
- Loss of energy
- Depression
- Sleeping disturbances
- Decreased work performance
References
- ↑ Khera M, Broderick GA, Carson CC, Dobs AS, Faraday MM, Goldstein I; et al. (2016). "Adult-Onset Hypogonadism". Mayo Clin Proc. 91 (7): 908–26. doi:10.1016/j.mayocp.2016.04.022. PMID 27343020.
- ↑ Basaria S (2014). "Male hypogonadism". Lancet. 383 (9924): 1250–63. doi:10.1016/S0140-6736(13)61126-5. PMID 24119423.
- ↑ Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS; et al. (2010). "Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline". J Clin Endocrinol Metab. 95 (6): 2536–59. doi:10.1210/jc.2009-2354. PMID 20525905.