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__NOTOC__
__NOTOC__
{{Vitamin D deficiency}}
{{CMG}} {{AE}} {{SSH}}


==Overview==
[[Sandbox: wdx]]
Common causes of vitamin D deficiency are inadequate vitamin D skin production, less dietary vitamin D intake and impaired absorption. Other causes of vitamin D deficiency include vitamin D loss, abnormal metabolism, resistance to vitamin D and medication. <ref name="pmid23790560">{{cite journal| author=Hossein-nezhad A, Holick MF| title=Vitamin D for health: a global perspective. | journal=Mayo Clin Proc | year= 2013 | volume= 88 | issue= 7 | pages= 720-55 | pmid=23790560 | doi=10.1016/j.mayocp.2013.05.011 | pmc=3761874 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23790560  }} </ref>


==Causes==
[[Xyz]]
Vitamin D deficiency may be caused by: <ref name="pmid23790560">{{cite journal| author=Hossein-nezhad A, Holick MF| title=Vitamin D for health: a global perspective. | journal=Mayo Clin Proc | year= 2013 | volume= 88 | issue= 7 | pages= 720-55 | pmid=23790560 | doi=10.1016/j.mayocp.2013.05.011 | pmc=3761874 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23790560  }} </ref>
* Inadequate vitamin D skin production
* Inadequate vitamin D dietary intake
* Vitamin D loss
* Malabsorption
* Impaired metabolism
* Resistance to Vitamin D
* Medication
===Common causes===
* Antiepileptic medication <ref name="pmid15123008">{{cite journal| author=Pack AM, Morrell MJ| title=Epilepsy and bone health in adults. | journal=Epilepsy Behav | year= 2004 | volume= 5 Suppl 2 | issue=  | pages= S24-9 | pmid=15123008 | doi=10.1016/j.yebeh.2003.11.029 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15123008  }} </ref>
* Glucocorticoid <ref name="pmid16691293">{{cite journal| author=Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG et al.| title=Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. | journal=J Clin Invest | year= 2006 | volume= 116 | issue= 6 | pages= 1703-12 | pmid=16691293 | doi=10.1172/JCI27793 | pmc=1459072 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16691293  }} </ref>
* Inadequate sun exposure including dark skin and clothing <ref name="pmid22525849">{{cite journal| author=Holick MF| title=Vitamin D: extraskeletal health. | journal=Rheum Dis Clin North Am | year= 2012 | volume= 38 | issue= 1 | pages= 141-60 | pmid=22525849 | doi=10.1016/j.rdc.2012.03.013 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22525849  }} </ref>
* Inadequate vitamin D dietary intake
===Less common cause===
* Autosomal-dominant hypophosphatemic rickets
* Celiac disease
* Chronic kidney disease: impaired renal 1α-hydroxylation <ref name="pmid19255004">{{cite journal| author=Ali FN, Arguelles LM, Langman CB, Price HE| title=Vitamin D deficiency in children with chronic kidney disease: uncovering an epidemic. | journal=Pediatrics | year= 2009 | volume= 123 | issue= 3 | pages= 791-6 | pmid=19255004 | doi=10.1542/peds.2008-0634 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19255004  }} </ref>
* Crohn disease <ref name="pmid17079566">{{cite journal| author=Pappa HM, Gordon CM, Saslowsky TM, Zholudev A, Horr B, Shih MC et al.| title=Vitamin D status in children and young adults with inflammatory bowel disease. | journal=Pediatrics | year= 2006 | volume= 118 | issue= 5 | pages= 1950-61 | pmid=17079566 | doi=10.1542/peds.2006-0841 | pmc=3205440 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17079566  }} </ref><ref name="pmid4050723">{{cite journal| author=Lo CW, Paris PW, Clemens TL, Nolan J, Holick MF| title=Vitamin D absorption in healthy subjects and in patients with intestinal malabsorption syndromes. | journal=Am J Clin Nutr | year= 1985 | volume= 42 | issue= 4 | pages= 644-9 | pmid=4050723 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4050723  }} </ref>
* Cystic fibrosis
* Highly active antiretroviral therapy (HAART)
* Hyperthyroidism
* Impaired enterohepatic circulation
* Nephrotic syndrome
* Post gastric bypass surgery
* Primary hyperparathyroidism
* Rifampin
* Sarcoidosis
* Severe liver failure: impaired hepatic 25-hydroxylation
* Short bowel syndrome
* St John's wort
* Tuberculosis
* Type I hereditary vitamin D–dependent rickets
* Type II hereditary vitamin D–dependent rickets
* Vitamin D-resistant rickets
* Whipple disease
* X-linked familial hypophosphatemia


===Causes by organ system===
[[Abc]]
{| style="width:80%; height:100px" border="1"
# [[Sandbox:Preeti]]
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular'''
# [[Lymphoma]]
| style="width:75%" bgcolor="Beige" ; border="1" | No underlying causes
# [[Breast lumps differential diagnosis]]
# [[Neck masses differential diagnosis]]
# [[Leukemia]]
{| class="wikitable"
|+
|-
|-
| bgcolor="LightSteelBlue" | '''Chemical/Poisoning'''
| colspan="2" |[[:Category:Risk calculator]]
| bgcolor="Beige" | No underlying causes
[[Category:Risk calculator]]
|-
|-
|- bgcolor="LightSteelBlue"
| colspan="2" |[[Deep vein thrombosis assessment of clinical probability and risk scores]]
| '''Dental'''
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
| colspan="2" |[[Pulmonary embolism assessment of clinical probability and risk scores]]
| '''Dermatologic'''
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Padua prediction score]]
| '''Drug Side Effect'''
|[[widget:PaduaVTEscore]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[IMPROVE risk score calculator]]
| '''Ear Nose Throat'''
|[[Widget:IMPROVEScore]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[IMPROVEDD risk score calculator]]
| '''Endocrine'''
|[[Widget:IMPROVEDDScore]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Caprini score calculator]]
| '''Environmental'''
|[[Widget:CapCal]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Wells score calculator for DVT]]
| '''Gastroenterologic'''
|[[Widget:DVT Wells score calculator]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Modified Wells score calculator for DVT]]
| '''Genetic'''
|[[Widget:DVT Modified Wells score calculator]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Pulmonary embolism Wells score calculator]]
| '''Hematologic'''
|[[widget:PE_calculator]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Pulmonary embolism modified Wells score calculator]]
| '''Iatrogenic'''
|[[Widget:PE Modified Wells score calculator]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[AMUSE score calculator]]
| '''Infectious Disease'''
|[[Widget:AMUSE_score_calculator]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[HAMILTON score calculator]]
| '''Musculoskeletal/Orthopedic'''
|[[Widget:HAMILTON_score_calculator]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Geneva score calculator]]
| '''Neurologic'''
|[[Widget:Geneva_score_calculator]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Revised Geneva score calculator]]
| '''Nutritional/Metabolic'''
|[[Widget:Revised_Geneva_score_calculator]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Simplified Geneva Score calculator]]
| '''Obstetric/Gynecologic'''
|[[Widget:Simplified_Geneva_score_calculator]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[TIMI Risk Score for Unstable Angina or NSTEMI]]
| '''Oncologic'''
|[[Widget:TIMI_UA_NSTEMI]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[TIMI Risk Score for STEMI]]
| '''Ophthalmologic'''
|[[Widget:TIMI_STEMI]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Tygerberg score]]
| '''Overdose/Toxicity'''
|[[widget:Tygerberg_score]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[CHA2DS2-VASc Score]]
| '''Psychiatric'''
|[[Widget:CHA2DS2VASc]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[CHADS2 score]]
| '''Pulmonary'''
|[[Widget:CHADS2score]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[HAS-BLED score]]
| '''Renal/Electrolyte'''
|[[Widget:HASBLEDscore]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[The GRACE risk score]]
| '''Rheumatology/Immunology/Allergy'''
|[[Widget:GRACEscore]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|
| '''Sexual'''
|
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Ranson criteria]]
| '''Trauma'''
[[Acute pancreatitis diagnostic criteria]]
| bgcolor="Beige" | No underlying causes
|[[Widget:RansonScore]]
|-
|-
|- bgcolor="LightSteelBlue"
|[[Apgar score]]
| '''Urologic'''
|[[Widget:Apgarscore]]
| bgcolor="Beige" | No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|[[Glasgow coma scale]]
| '''Miscellaneous'''
|[[Widget:Adult_GCS]]
| bgcolor="Beige" | No underlying causes
|-
|-
|[[Pediatric Glasgow Coma Scale]]
|[[Widget:PGCS]]
|-
|[[Cincinnati stroke scale]]
|[[Widget:Cincinnati_Stroke_Scale]]
|-
|[[DIPSS Plus Score]]
|[[Widget:DIPSS_Plus_Score]]
|-
| colspan="2" |[[ICU scoring systems]]
|-
|[[APACHE II]]
|[[Widget:APACHEII]]
|-
|[[SAPS II]]
|[[Widget:SAPSII]]
|-
|[[SAPS III]]
|[[Widget:SAPSIII]]
|-
|[[PIM2]]
|
|}
|}
==Table==
{|
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Complications
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Polymyositis
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Dermatomyositis
|-
! align="center" style="background:#DCDCDC;" + |[[Cancer|Malignancy]]
| align="left" style="background:#F5F5F5;" + |
*[[Lung]]
| align="left" style="background:#F5F5F5;" + |
*[[Lung]]
|}
<br>
===Calculation of the Padua Prediction Score===
Shown below is a calculator using the predictive score for VTE among hospitalized medical patients. Check all boxes that apply to your patient:


===Causes in alphabetical order===
{| style="border: 0; float: left; width: 45%; position: float; background: #104E8B; border-radius: 10px 10px 10px 10px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5); margin: 0 0 0 0; padding: 5px 5px; font-weight: bold;"
{{columns-list|3|
| colspan="2" style="text-align: center; color: #FFFFFF; font-size: 120%;" | IMPROVE Bleeding Risk Score
* Autosomal-dominant hypophosphatemic rickets
|-
* Carbamazepine
! style=" text-align: left; color: #4479BA; background: #FFFFFF; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 0 0 rgba(0, 0, 0, 0.2); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Variable
* Celiac disease
! style=" text-align: center; color: #4479BA; background: #FFFFFF; border-radius: 5px 5px 5px 5px; text-shadow: 0 0 0 rgba(0, 0, 0, 0.2); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Score
* Chronic kidney disease
|-
* Crohn disease
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Active gastric or duodenal ulcer
* Cystic fibrosis
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |4.5
* Glucocorticoid
|-
* Highly active antiretroviral therapy (HAART)
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Prior bleeding within the last 3 months
* Hyperthyroidism
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |4
* Impaired enterohepatic circulation
|-
* Inadequate sun exposure
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Thrombocytopenia (<50x10<sup>9</sup>/L)
* Inadequate vitamin D dietary intake
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |4
* Nephrotic syndrome
|-
* Phenobarbital
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Age ≥ 85 years
* Phenytoin
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |3.5
* Post gastric bypass surgery
|-
* Primary hyperparathyroidism
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Liver failure (INR>1.5)
* Primidone
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |2.5
* Rifampin
|-
* Sarcoidosis
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Severe kidney failure (GFR< 30 mL/min/m<sup>2</sup>)
* Severe liver failure
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |2.5
* Short bowel syndrome
|-
* St John's wort
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Admission to ICU or CCU
* Tuberculosis
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |2.5
* Type I hereditary vitamin D–dependent rickets
|-
* Type II hereditary vitamin D–dependent rickets
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Central venous catheter
* Valproate
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |2
* Vitamin D-resistant rickets
|-
* Whipple disease
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Rheumatic disease
* X-linked familial hypophosphatemia
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |2
}}
|-
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Active malignancy
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |2
|-
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Age: 40-84 years
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |1.5
|-
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Male
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |1
|-
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Moderate kidney failure (GFR: 30-59 mL/min/m<sup>2</sup>)
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |1
|-
! colspan="2" style=" text-align: left; color: #4479BA; background: #FFFFFF; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 0 0 rgba(0, 0, 0, 0.2); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Result:
|-
! colspan="2" style=" text-align: left; color: #4479BA; background: #FFFFFF; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 0 0 rgba(0, 0, 0, 0.2); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Interpretation:
|}
<br style="clear:left" />


==References==
===Calculation of the test Prediction Score===
{{reflist|2}}
Shown below is a calculator using the predictive score for VTE among hospitalized medical patients. Check all boxes that apply to your patient:


[[Category:Disease]]
{| style="border: 0; float: left; width: 45%; position: float; background: #104E8B; border-radius: 10px 10px 10px 10px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5); margin: 0 0 0 0; padding: 5px 5px; font-weight: bold;"
[[Category:Endocrinology]]
| colspan="2" style="text-align: center; color: #FFFFFF; font-size: 120%;" | IMPROVE Bleeding Risk Score
|-
! style=" text-align: left; color: #4479BA; background: #FFFFFF; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 0 0 rgba(0, 0, 0, 0.2); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Variable
! style=" text-align: center; color: #4479BA; background: #FFFFFF; border-radius: 5px 5px 5px 5px; text-shadow: 0 0 0 rgba(0, 0, 0, 0.2); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Score
|-
! rowspan="2" style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Gender
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Female
|-
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Male
|-
! rowspan="4" style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Age
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |0-70
|-
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |71-80
|-
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |81-90
|-
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |>90
|-
! rowspan="5" style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Hgb ('''g/dL)'''
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |>17 '''g/dL'''
|-
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |15.5-17 '''g/dL'''
|-
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |12.5-15.5 '''g/dL'''
|-
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |12.5-11 '''g/dL'''
|-
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |<11 '''g/dL'''
|-
! rowspan="2" style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |CrCl (mL/min)
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |30-60 mL/min
|-
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |15-30 mL/min
|-
! rowspan="2" style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Albumin
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |>3.5 g/dL
|-
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |≤3.5 g/dL
|-
! rowspan="2" style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |D-dimer
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |≥1 µg/mL
|-
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |<1 µg/mL
|-
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |ICU admission
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |
|-
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Acute stroke on hospitalization
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |
|-
! style=" text-align: left; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |History of VTE
| style=" text-align: center; color: #FFFFFF; background: #4479BA; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |
|-
! colspan="2" style=" text-align: left; color: #4479BA; background: #FFFFFF; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 0 0 rgba(0, 0, 0, 0.2); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Result:
|-
! colspan="2" style=" text-align: left; color: #4479BA; background: #FFFFFF; padding: 2px 10px; border-radius: 5px 5px 5px 5px; text-shadow: 0 0 0 rgba(0, 0, 0, 0.2); box-shadow: 0 1px 1px rgba(0, 0, 0, 0.5);" |Interpretation:
|}
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===Interpretation of the Padua Prediction Score===
{{WikiDoc Sources}}
The interpretation of the score is as follows:
* Score ≥ 4: High risk for VTE
* Score < 4: Low risk for VTE
==References==
<references />

Latest revision as of 18:11, 14 January 2019


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Category:Risk calculator
Deep vein thrombosis assessment of clinical probability and risk scores
Pulmonary embolism assessment of clinical probability and risk scores
Padua prediction score widget:PaduaVTEscore
IMPROVE risk score calculator Widget:IMPROVEScore
IMPROVEDD risk score calculator Widget:IMPROVEDDScore
Caprini score calculator Widget:CapCal
Wells score calculator for DVT Widget:DVT Wells score calculator
Modified Wells score calculator for DVT Widget:DVT Modified Wells score calculator
Pulmonary embolism Wells score calculator widget:PE_calculator
Pulmonary embolism modified Wells score calculator Widget:PE Modified Wells score calculator
AMUSE score calculator Widget:AMUSE_score_calculator
HAMILTON score calculator Widget:HAMILTON_score_calculator
Geneva score calculator Widget:Geneva_score_calculator
Revised Geneva score calculator Widget:Revised_Geneva_score_calculator
Simplified Geneva Score calculator Widget:Simplified_Geneva_score_calculator
TIMI Risk Score for Unstable Angina or NSTEMI Widget:TIMI_UA_NSTEMI
TIMI Risk Score for STEMI Widget:TIMI_STEMI
Tygerberg score widget:Tygerberg_score
CHA2DS2-VASc Score Widget:CHA2DS2VASc
CHADS2 score Widget:CHADS2score
HAS-BLED score Widget:HASBLEDscore
The GRACE risk score Widget:GRACEscore
Ranson criteria

Acute pancreatitis diagnostic criteria

Widget:RansonScore
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Glasgow coma scale Widget:Adult_GCS
Pediatric Glasgow Coma Scale Widget:PGCS
Cincinnati stroke scale Widget:Cincinnati_Stroke_Scale
DIPSS Plus Score Widget:DIPSS_Plus_Score
ICU scoring systems
APACHE II Widget:APACHEII
SAPS II Widget:SAPSII
SAPS III Widget:SAPSIII
PIM2

Table

Complications Polymyositis Dermatomyositis
Malignancy


Calculation of the Padua Prediction Score

Shown below is a calculator using the predictive score for VTE among hospitalized medical patients. Check all boxes that apply to your patient:

IMPROVE Bleeding Risk Score
Variable Score
Active gastric or duodenal ulcer 4.5
Prior bleeding within the last 3 months 4
Thrombocytopenia (<50x109/L) 4
Age ≥ 85 years 3.5
Liver failure (INR>1.5) 2.5
Severe kidney failure (GFR< 30 mL/min/m2) 2.5
Admission to ICU or CCU 2.5
Central venous catheter 2
Rheumatic disease 2
Active malignancy 2
Age: 40-84 years 1.5
Male 1
Moderate kidney failure (GFR: 30-59 mL/min/m2) 1
Result:
Interpretation:


Calculation of the test Prediction Score

Shown below is a calculator using the predictive score for VTE among hospitalized medical patients. Check all boxes that apply to your patient:

IMPROVE Bleeding Risk Score
Variable Score
Gender Female
Male
Age 0-70
71-80
81-90
>90
Hgb (g/dL) >17 g/dL
15.5-17 g/dL
12.5-15.5 g/dL
12.5-11 g/dL
<11 g/dL
CrCl (mL/min) 30-60 mL/min
15-30 mL/min
Albumin >3.5 g/dL
≤3.5 g/dL
D-dimer ≥1 µg/mL
<1 µg/mL
ICU admission
Acute stroke on hospitalization
History of VTE
Result:
Interpretation:


Interpretation of the Padua Prediction Score

The interpretation of the score is as follows:

  • Score ≥ 4: High risk for VTE
  • Score < 4: Low risk for VTE

References