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{{CMG}} {{shyam}}; {{AE}} {{Anmol}}, {{Akram}}, {{ZAS}} , {{Sali}}, {{Sab}}
 
 


{{SK}} Immune deficiency; immunity suppression; immunological deficiency; immunosuppression
{{SK}} Immune deficiency; immunity suppression; immunological deficiency; immunosuppression
==Overview==
Immunodeficiency can be caused by a variety of conditions including autoimmunity, infections, congenital defects, complement defects, or auto-inflammatory states.


==[[Immunodeficiency overview|Overview]]==
==Classification==
==[[Immunodeficiency historical perspective|Historical Perspective]]==
<div style="width: 80%; font-size: 85%;">
==[[Immunodeficiency classification|Classification]]==
<small>
==[[Immunodeficiency pathophysiology|Pathophysiology]]==
{{Family tree/start}}
==[[Immunodeficiency causes|Causes]]==
{{Family tree| | | | | | | | | | | | | | | | | A01 | | | | | | | | |A01=Immunodeficiency}}
==[[Immunodeficiency differential diagnosis|Differentiating Immunodeficiency from other Diseases]]==
{{Family tree| |,|-|-|-|v|-|-|-|v|-|-|-|v|-|-|-|+|-|-|-|v|-|-|-|v|-|-|-|v|-|-|-|.| }}
==[[Immunodeficiency epidemiology and demographics|Epidemiology and Demographics]]==
{{Family tree| B01 | | B02 | | B03 | | B04 | | B05 | | B06 | | B07 | | B08 | | B09 | |B01=[[Immunodeficiency affecting cellular and humoral Immunity]]|B02=[[Combined immunodeficiency]]|B03=[[Predominantly antibody deficiency]]|B04=[[Diseases of immune dysregulation]]|B05=[[Congenital defects of phagocytes]]|B06=[[Defects in intrinsic and innate immunity]]|B07=[[Auto-inflammatory disorders]]|B08=[[Complement deficiencies]]|B09=[[Phenocopies of primary immunodeficiency]] (PID)}}
==[[Immunodeficiency risk factors|Risk Factors]]==
{{Family tree|!| | | |!| | | |!| | | |!| | | |!| | | |!| | | | | | | | | | | | | | | | |}}
==[[Immunodeficiency screening|Screening]]==
{{Family tree|)| C01 |)| D01 |)| E01 |)| F01 |)| G01 |)| H01 | | | | | | | | | | | | | |C01=Severe combined<br>immunodeficiency (SCID)|D01=Combined immunodeficiency<br>with associated features|E01=Hypogammaglobulinemia|F01=Hemophagocytic lymphohistiocytosis (HLH)<br>& EBV susceptibility|G01=Congenital defects of<br>phagocyte number|H01=Bacterial and<br>parasitic infections}}
==[[Immunodeficiency_natural_history,_complications_and_prognosis|Natural History, Complications, and Prognosis]]==
{{Family tree|!| | | |!| | | |!| | | |!| | | |!| | | |!| | | | | | | | | | | | | | | | |}}
==Diagnosis==
{{Family tree|`| C02 |`| D02 |`| E02 |`| F02 |`| G02 |`| H02 | | | | | | | | | | | | | |C02=Combined immunodeficiencies<br>generally less pronounced than<br>severe combined immunodeficiency|D02=Combined immunodeficiency<br>with syndromic features|E02=Other antibody<br>deficiencies|F02= Syndromes with<br>autoimmunity and others|G02=Congenital defects of<br>phagocyte function|H02=Mendelian susceptibility to<br>mycobacterial disease (MSMD)<br>& viral infections}}
:[[Immunodeficiency history and symptoms|History and Symptoms]] | [[Immunodeficiency physical examination|Physical Examination]] | [[Immunodeficiency laboratory findings|Laboratory Findings]] | [[Immunodeficiency electrocardiogram|Electrocardiogram]] | [[Immunodeficiency chest x ray|Chest X Ray]] | [[Immunodeficiency CT|CT]] | [[Immunodeficiency MRI|MRI]] | [[Immunodeficiency_echocardiography_or_ultrasound|Echocardiography or Ultrasound]] | [[Immunodeficiency other imaging findings|Other Imaging Findings]] | [[Immunodeficiency other diagnostic studies|Other Diagnostic Studies]]
{{Family tree/end}}
==Treatment==
</div>
:[[Immunodeficiency medical therapy|Medical Therapy]] | [[Immunodeficiency surgery|Surgery]] | [[Immunodeficiency primary prevention|Primary Prevention]] | [[Immunodeficiency secondary prevention|Secondary Prevention]] | [[Immunodeficiency cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Immunodeficiency future or investigational therapies|Future or Investigational Therapies]]
</small>
==Case Studies==
==References==
:[[Immunodeficiency case study one|Case #1]]
{{Reflist|2}}
 
{{Immune_system}}
{{Immune disorders}}


[[Category:Immune system disorders]]
[[Category:Immunodeficiency| ]]
[[Category:Hematology]]
[[Category:Hematology]]
 
[[Category:Medicine]]
[[ca:Immunodeficiència]]
[[Category:Immunology]]
[[de:Immundefekt]]
[[Category:Up-To-Date]]
[[el:Ανοσολογική ανεπάρκεια]]
[[es:Inmunodeficiencia]]
[[fr:Immunodépression]]
[[he:כשל חיסוני]]
[[pt:Imunodeficiência]]
 
{{WH}}
{{WS}}
 
[[Category:Disease]]

Latest revision as of 22:21, 29 July 2020

Immunodeficiency
ICD-10 D84.9
ICD-9 279.3
DiseasesDB 21506
MeSH D007153

Immunodeficiency Main Page

Home

Overview

Classification

Immunodeficiency Affecting Cellular and Humoral Immunity

Combined Immunodeficiency

Predominantly Antibody Deficiency

Diseases of Immune Dysregulation

Congenital Defects of Phagocytes

Defects in Intrinsic and Innate Immunity

Auto-inflammatory Disorders

Complement Deficiencies

Phenocopies of Primary Immunodeficiency

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[3], Ali Akram, M.B.B.S.[4], Zahir Ali Shaikh, MD[5] , Syed Musadiq Ali M.B.B.S.[6], Sabawoon Mirwais, M.B.B.S, M.D.[7]


Synonyms and keywords: Immune deficiency; immunity suppression; immunological deficiency; immunosuppression

Overview

Immunodeficiency can be caused by a variety of conditions including autoimmunity, infections, congenital defects, complement defects, or auto-inflammatory states.

Classification

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Immunodeficiency
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Immunodeficiency affecting cellular and humoral Immunity
 
Combined immunodeficiency
 
Predominantly antibody deficiency
 
Diseases of immune dysregulation
 
Congenital defects of phagocytes
 
Defects in intrinsic and innate immunity
 
Auto-inflammatory disorders
 
Complement deficiencies
 
Phenocopies of primary immunodeficiency (PID)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Severe combined
immunodeficiency (SCID)
 
 
Combined immunodeficiency
with associated features
 
 
Hypogammaglobulinemia
 
 
Hemophagocytic lymphohistiocytosis (HLH)
& EBV susceptibility
 
 
Congenital defects of
phagocyte number
 
 
Bacterial and
parasitic infections
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Combined immunodeficiencies
generally less pronounced than
severe combined immunodeficiency
 
 
Combined immunodeficiency
with syndromic features
 
 
Other antibody
deficiencies
 
 
Syndromes with
autoimmunity and others
 
 
Congenital defects of
phagocyte function
 
 
Mendelian susceptibility to
mycobacterial disease (MSMD)
& viral infections
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

References

Retrieved from "https://www.wikidoc.org/index.php?title=Immunodeficiency&oldid=1639760"