Congenital syphilis differential diagnosis: Difference between revisions
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Latest revision as of 21:04, 29 July 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aravind Kuchkuntla, M.B.B.S[2]
Overview
Congenital syphilis must be differentiated from other TORCH infections.
Differential Diagnosis
The most important congenital infections, which can be transmitted vertically from mother to fetus are the TORCH infections. These infections have overlapping features and hence, must be differentiated from congenital syphilis :[1][2]
| Congenital Infection | Cardiac Findings | Skin Findings | Ocular Findings | Hepatosplenomegaly | Hydrocephalus | Microcephaly | Intracranial Calcifications | Hearing deficits |
|---|---|---|---|---|---|---|---|---|
| Toxoplasmosis | ✔ | ✔ | ✔ | Diffuse intracranial calcifications | ||||
| Congenital Syphils | ✔ | |||||||
| Rubella | ✔ | ✔ | ✔ | ✔ | ||||
| Cytomegalovirus (CMV) | ✔ | ✔ | ✔ | Periventricular calcifications | ✔ | |||
| Herpes simplex virus (HSV) | ✔ | ✔ | ✔ | ✔ | ||||
| Parvovirus B19 | ✔ |
References
- ↑ Neu N, Duchon J, Zachariah P (2015). "TORCH infections". Clin Perinatol. 42 (1): 77–103, viii. doi:10.1016/j.clp.2014.11.001. PMID 25677998.
- ↑ Ajij M, Nangia S, Dubey BS (2014). "Congenital rubella syndrome with blueberry muffin lesions and extensive metaphysitis". J Clin Diagn Res. 8 (12): PD03–4. doi:10.7860/JCDR/2014/10271.5293. PMC 4316306. PMID 25654000.