Hashimoto's thyroiditis laboratory findings: Difference between revisions
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===Diagnostic findings of Hashimoto's thyroiditis=== | ===Diagnostic findings of Hashimoto's thyroiditis=== | ||
{| class="wikitable" | {| class="wikitable" | ||
| rowspan="2" |Thyroid function test | | rowspan="2" |[[Thyroid function test]] | ||
|'''''↓'''''TSH '''↑''' T3 and T4 | |'''''↓'''''[[TSH]] '''↑''' [[T3]] and [[T4]] | ||
|In transient hyperthyroidism | |In transient hyperthyroidism | ||
|- | |- | ||
|'''↑''' TSH '''''↓''''' T3 and T4 | |'''↑''' [[TSH]] '''''↓''''' [[T3]] and [[T4]] | ||
|In the hypothyroid state | |In the hypothyroid state | ||
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|- | |- | ||
|[[Radioiodine]] reuptake | |[[Radioiodine]] reuptake | ||
|I-123 reuptake | |[[I-123 thyroid imaging|I-123]] reuptake | ||
|'''''↓''''' | |'''''↓''''' | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
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[[Category:Medicine]] | |||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Up-To-Date]] | |||
Latest revision as of 21:58, 29 July 2020
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Hashimoto's thyroiditis Microchapters |
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Hashimoto's thyroiditis laboratory findings On the Web |
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American Roentgen Ray Society Images of Hashimoto's thyroiditis laboratory findings |
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Risk calculators and risk factors for Hashimoto's thyroiditis laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
Laboratory findings consistent with the diagnosis of Hashimoto's thyroiditis usually include increased thyroid stimulating hormone, decreased free T3 and free T4, and anti-thyroid peroxidase antibodies.
Laboratory Findings
Laboratory findings consistent with the diagnosis of Hashimoto's thyroiditis usually include increased thyroid stimulating hormone, decreased free T3 and free T4, and Anti-thyroid peroxidase antibodies.[1][2]
Thyroid hormones
- Increased Thyroid-stimulating hormone (TSH)
- Decreased Free T3 and Free T4
- TSH may be decreased in the transient hyperthyroid state[3]
Thyroid antibodies
- Anti-thyroid peroxidase antibodies (anti-TPO) (correlates with the disease severity)
- Anti-thyroglobulin antibodies (anti-Tg)
- Anti-microsomal antibodies can help obtain an accurate diagnosis[4]
Diagnostic findings of Hashimoto's thyroiditis
| Thyroid function test | ↓TSH ↑ T3 and T4 | In transient hyperthyroidism |
| ↑ TSH ↓ T3 and T4 | In the hypothyroid state | |
| Antibodies | Anti-thyroid peroxidase antibodies | Positive |
| Anti-thyroglobulin antibodies | Positive | |
| Anti-microsomal antibodies | Positive | |
| Radioiodine reuptake | I-123 reuptake | ↓ |
References
- ↑ Dong YH, Fu DG (2014). "Autoimmune thyroid disease: mechanism, genetics and current knowledge". Eur Rev Med Pharmacol Sci. 18 (23): 3611–8. PMID 25535130.
- ↑ Caturegli P, De Remigis A, Rose NR (2014). "Hashimoto thyroiditis: clinical and diagnostic criteria". Autoimmun Rev. 13 (4–5): 391–7. doi:10.1016/j.autrev.2014.01.007. PMID 24434360.
- ↑ Simmons, PJ (1998). "Antigen-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1beta and interleukin-6". Endocrinology. 139 (7): 3158–3186. doi:10.1210/en.139.7.3148. PMID 9645688.
- ↑ Giannini, AJ (1986). The Biological Foundations of Clinical Psychiatry. New Hyde Park, NY: Medical Examination Publishing Company. pp. 193–198. ISBN 0-87488-449-7.