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| ==Overview== | | ==Overview== |
| Toxic multinodular goiter is classified into three types- Primary, secondary, tertiary hyperthyroidism. Primary hyperthyroidism is further divided into grave’s disease, toxic thyroid nodule, thyroid adenoma, multinodular goiter. Secondary hyperthyroidism is divided into pituitary adenoma, intracranial tumors pressing pituitary gland. Tertiary hyperthyroidism is divided into intracranial tumors or masses involving hypothalamus.
| | There is no established system for the classification of toxic multinodular goiter. |
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| ==Classification== | | ==Classification== |
| | | There is no established system for the classification of toxic multinodular goiter. |
| ===Based on the origin of the abnormality===
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| Based on the origin of the abnormality the lesions may be classified into primary, secondary, and tertiary hyperthyroidism.<ref name="pmid12679417">{{cite journal |vauthors=Monaco F |title=Classification of thyroid diseases: suggestions for a revision |journal=J. Clin. Endocrinol. Metab. |volume=88 |issue=4 |pages=1428–32 |year=2003 |pmid=12679417 |doi=10.1210/jc.2002-021260 |url=}}</ref>
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| {{familytree/start}}
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| {{familytree | | | | | | | | | A01 | | | | | |A01='''According to the origin of the abnormality'''}}
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| {{familytree | | | | | | | | | |!| | | | | | | | }}
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| {{familytree | | |,|-|-|-|-|-|-|+|-|-|-|-|-|-|.| }}
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| {{familytree | | B01 | | | | | B02 | | | | | B03 |B01='''Primary hyperthyroidism'''|B02='''Secondary hyperthyroidism'''|B03='''Tertiary hyperthyroidism'''|}}
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| {{familytree | | |!| | | | | | |!| | | | | | |!| |}}
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| {{familytree | |boxstyle=text-align: left; | C01 | | | | | C02 | | | | | C03 | |C01=• [[Graves' disease|Grave’s disease]]<br>• [[Toxic thyroid nodule]]<br>• [[Thyroid adenoma]]<br>• [[Multinodular goiter]]|C02=• [[Pituitary adenoma]]<br>• [[Intracranial tumor|Intracranial tumors]] pressing [[pituitary gland]]|C03=• [[Intracranial tumor|Intracranial tumors]] or [[Intracranial mass|masses]] involving [[hypothalamus]]}}
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| {{familytree/end}}
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| ===Based on the iodine uptake===
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| Based on the results of iodine uptake, thyroid disorders may be classified into high uptake, high or normal uptake, and low uptake.<ref name="urlThyroid disease classification - The Lancet">{{cite web |url=+http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)72981-0/abstract |title=Thyroid disease classification - The Lancet |format= |work= |accessdate=}}</ref>
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| {{familytree/start}}
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| {{familytree | | | | | | | | | A01 | | | | | |A01='''According to iodine uptake'''}}
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| {{familytree | | | | | | | | | |!| | | | | | | | }}
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| {{familytree | | |,|-|-|-|-|-|-|+|-|-|-|-|-|-|.| }}
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| {{familytree | | B01 | | | | | B02 | | | | | B03 |B01='''High uptake'''|B02='''High or normal uptake'''|B03='''Low uptake'''|}}
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| {{familytree | | |!| | | | | | |!| | | | | | |!| |}}
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| {{familytree | |boxstyle=text-align: left; | C01 | | | | | C02 | | | | | C03 | |C01=• [[Toxic multinodular goiter]]<br>• [[Graves' disease]] <br>• [[Toxic thyroid adenoma]]<br>|C02=• Iodine caused hyperthyroidism<br>• [[Hashimoto's thyroiditis|Hashitoxicosis]]<br>• [[Germ cell tumors]] ([[choriocarcinoma]] in males and testicular germ cell tumors)<br>• [[Pituitary adenoma|Pituitary TSH producing adenoma]]|C03=• [[Subacute thyroiditis]]<br>• Hyperthyroidism due to ectopic [[thyroid]] tissue<br>• Factitious [[thyrotoxicosis]]<br>• [[Struma ovarii]]<br>• Painless [[thyroiditis]]<br>• Amiodarone induced [[thyroiditis]]-Type 1<br>• Amiodarone induced [[thyroiditis]]-Type 2}}
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| {{familytree/end}}
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| ==References== | | ==References== |