Mallory-Weiss syndrome pathophysiology: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Mallory-Weiss syndrome}} | {{Mallory-Weiss syndrome}} | ||
{{CMG}} {{AE}} {{DM}} | {{CMG}}; {{AE}} {{DM}} | ||
==Overview== | ==Overview== | ||
The exact pathogenesis of Mallory-Weiss syndrome is not fully understood. It is thought that Mallory-Weiss syndrome is the result of sudden increase in intraabdominal pressure that causes mucosal lacerations. | |||
==Pathogenesis== | |||
* The exact pathogenesis of Mallory-Weiss syndrome is not fully understood. | * The exact pathogenesis of Mallory-Weiss syndrome is not fully understood. | ||
* It is thought that Mallory-Weiss syndrome is the result of sudden increase in intraabdominal pressure that causes mucosal lacerations. If the tear involves the esophageal venous or arterial Plexus,bleeding occurs.<ref name="ByrneMoran1965">{{cite journal|last1=Byrne|first1=John J.|last2=Moran|first2=John M.|title=The Mallory-Weiss Syndrome|journal=New England Journal of Medicine|volume=272|issue=8|year=1965|pages=398–400|issn=0028-4793|doi=10.1056/NEJM196502252720805}}</ref><ref name="DeckerZamcheck1953">{{cite journal|last1=Decker|first1=John P.|last2=Zamcheck|first2=Norman|last3=Mallory|first3=G. Kenneth|title=Mallory-Weiss Syndrome|journal=New England Journal of Medicine|volume=249|issue=24|year=1953|pages=957–963|issn=0028-4793|doi=10.1056/NEJM195312102492401}}</ref> | * It is thought that Mallory-Weiss syndrome is the result of sudden increase in intraabdominal pressure that causes mucosal lacerations. If the tear involves the esophageal venous or arterial Plexus,bleeding occurs.<ref name="ByrneMoran1965">{{cite journal|last1=Byrne|first1=John J.|last2=Moran|first2=John M.|title=The Mallory-Weiss Syndrome|journal=New England Journal of Medicine|volume=272|issue=8|year=1965|pages=398–400|issn=0028-4793|doi=10.1056/NEJM196502252720805}}</ref><ref name="DeckerZamcheck1953">{{cite journal|last1=Decker|first1=John P.|last2=Zamcheck|first2=Norman|last3=Mallory|first3=G. Kenneth|title=Mallory-Weiss Syndrome|journal=New England Journal of Medicine|volume=249|issue=24|year=1953|pages=957–963|issn=0028-4793|doi=10.1056/NEJM195312102492401}}</ref> | ||
== Genetics == | |||
There are no genes involved in the pathogenesis of Mallory-Weiss syndrome. | |||
== Gross Pathology == | |||
On gross pathology, Mallory-Weiss tears may appear red longitudinal break in the mucosa, sometimes may extend into muscularis mucosa, and covered by a clot. Active bleeding may also be observed. | |||
==References== | ==References== | ||
Latest revision as of 14:45, 8 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Diab, MD [2]
Overview
The exact pathogenesis of Mallory-Weiss syndrome is not fully understood. It is thought that Mallory-Weiss syndrome is the result of sudden increase in intraabdominal pressure that causes mucosal lacerations.
Pathogenesis
- The exact pathogenesis of Mallory-Weiss syndrome is not fully understood.
- It is thought that Mallory-Weiss syndrome is the result of sudden increase in intraabdominal pressure that causes mucosal lacerations. If the tear involves the esophageal venous or arterial Plexus,bleeding occurs.[1][2]
Genetics
There are no genes involved in the pathogenesis of Mallory-Weiss syndrome.
Gross Pathology
On gross pathology, Mallory-Weiss tears may appear red longitudinal break in the mucosa, sometimes may extend into muscularis mucosa, and covered by a clot. Active bleeding may also be observed.
References
- ↑ Byrne, John J.; Moran, John M. (1965). "The Mallory-Weiss Syndrome". New England Journal of Medicine. 272 (8): 398–400. doi:10.1056/NEJM196502252720805. ISSN 0028-4793.
- ↑ Decker, John P.; Zamcheck, Norman; Mallory, G. Kenneth (1953). "Mallory-Weiss Syndrome". New England Journal of Medicine. 249 (24): 957–963. doi:10.1056/NEJM195312102492401. ISSN 0028-4793.