Ameloblastoma epidemiology and demographics: Difference between revisions

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{{Ameloblastoma}}
{{Ameloblastoma}}
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==Overview==
==Overview==
The incidence of ameloblastoma is approximately 1.96, 1.20, 0.18, and 0.44 per 100,000 for black males, black females, white males, and white females respectively worldwide. Ameloblastoma affects men and women equally. There is no racial predilection to the ameloblastoma. Ameloblastoma usually occur in middle age group i.e. 20-40 years: the median age at diagnosis is 39 years. <ref name="wiki">  Ameloblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Ameloblastoma Accessed on December 25, 2015</ref ><ref name="pmid3304226">{{cite journal| author=Toledo-Pereyra LH, Bergren CT| title=Liver preservation techniques for transplantation. | journal=Artif Organs | year= 1987 | volume= 11 | issue= 3 | pages= 214-23 | pmid=3304226 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3304226 }} </ref>
The [[incidence]] of [[ameloblastoma]] is approximately 1.96, 1.20, 0.18, and 0.44 per 100,000 for black males, black females, white males, and white females respectively, worldwide. [[Ameloblastoma]] affects men and women equally. There is no racial predilection to the [[ameloblastoma]]. [[Ameloblastoma]] usually occur in middle age group i.e. 20-40 years; the [[median]] age at diagnosis is 39 years.   
==Epidemiology and Demographics==
==Epidemiology and Demographics==
Ameloblastoma although rare, is the most common odontogenic tumor accounting for 1% of all oral tumors and around 18% of all odontogenic tumors. They are rare in children. Approximately, 8.7% - 15% of all ameloblastomas occur in children. Ameloblastoma occurs in all areas of jaws, but the mandible is the most commonly affected area i.e. more than 80% of cases are seen here. Within the mandible, the area commonly involved is near the angle of the mandible in the region of the 3rd molar tooth (the molar angle ramus area). It is involved three times more commonly than are anterior and premolar regions combined. Although benign, it is a locally aggressive neoplasm with a high rate of recurrence.<ref name="wiki"> Ameloblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Ameloblastoma Accessed on December 25, 2015</ref >
===Incidence===
===Incidence===  
* The [[incidence]] of [[ameloblastoma]] is approximately 0.5 new cases in 1,000,000 people, worldwide.<ref name="KreppelZöller2018">{{cite journal|last1=Kreppel|first1=M|last2=Zöller|first2=J|title=Ameloblastoma-Clinical, radiological, and therapeutic findings|journal=Oral Diseases|volume=24|issue=1-2|year=2018|pages=63–66|issn=1354523X|doi=10.1111/odi.12702}}</ref>
The  annual incidence of ameloblastoma is approximately 1.96, 1.20, 0.18, and 0.44 per 100,000 for black males, black females, white males, and white females respectively worldwide.
 
===Gender===
===Gender===
Ameloblastoma affects men and women equally. Although, women tend to be 4 years younger than men when tumors first occur and tumors appear to be larger in females.<ref name="pmid3304226">{{cite journal| author=Toledo-Pereyra LH, Bergren CT| title=Liver preservation techniques for transplantation. | journal=Artif Organs | year= 1987 | volume= 11 | issue= 3 | pages= 214-23 | pmid=3304226 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3304226  }} </ref>
* [[Ameloblastoma]] affects men and women almost equally. Although, women tend to be 4 years younger than men when tumors first occur and tumors appear to be larger in females.<ref name="pmid3304226">{{cite journal| author=Toledo-Pereyra LH, Bergren CT| title=Liver preservation techniques for transplantation. | journal=Artif Organs | year= 1987 | volume= 11 | issue= 3 | pages= 214-23 | pmid=3304226 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3304226  }} </ref>
* The male to female ratio is approximately 1.2:1.<ref name="KreppelZöller20182">{{cite journal|last1=Kreppel|first1=M|last2=Zöller|first2=J|title=Ameloblastoma-Clinical, radiological, and therapeutic findings|journal=Oral Diseases|volume=24|issue=1-2|year=2018|pages=63–66|issn=1354523X|doi=10.1111/odi.12702}}</ref>
 
===Race===
===Race===
There is no racial predilection to the ameloblastoma. However, there is conflicting evidence on the incidence rates in different races. Although some reports claim an increased incidence of ameloblastoma in black individuals, a large study identifies Asians as the population with greatest number of affected patients. Ameloblastoma is by far the most common unequivocal odontogenic neoplasm in all ethnic groups, representing approximately 1% of head and neck neoplasms in Europe and the USA, some studies claim that it has the highest incidence in Afro-Caribbean populations.<ref name="Morgan2011">{{cite journal|last1=Morgan|first1=Peter R.|title=Odontogenic tumors: a review|journal=Periodontology 2000|volume=57|issue=1|year=2011|pages=160–176|issn=09066713|doi=10.1111/j.1600-0757.2011.00393.x}}</ref>
* There is no racial predilection to the [[ameloblastoma]]. However, there is conflicting evidence on the incidence rates in different races.
* Although some reports claim an increased incidence of [[ameloblastoma]] in black individuals, a large study identifies Asians as the population with greatest number of affected patients.  
* [[Ameloblastoma]] is by far the most common unequivocal odontogenic [[neoplasm]] in all ethnic groups, representing approximately 1% of head and neck neoplasms in Europe and the USA, some studies claim that it has the highest incidence in Afro-Caribbean populations.<ref name="Morgan2011">{{cite journal|last1=Morgan|first1=Peter R.|title=Odontogenic tumors: a review|journal=Periodontology 2000|volume=57|issue=1|year=2011|pages=160–176|issn=09066713|doi=10.1111/j.1600-0757.2011.00393.x}}</ref>


===Age===
===Age===
They are slow growing and tend to present in the 3rd to 5th decades of life. Ameloblastoma usually occur in middle age group i.e. 20-40 years: the median age at diagnosis is 39 years. Maxillary and extraosseous ameloblastoma commonly affects individuals in a slightly older age group while unicystic and granular cell ameloblastoma occur in a younger age group. The average age of unicystic ameloblastoma is 10.8 years.
* [[Ameloblastoma]] commonly affects adults than younger people, the median age at diagnosis is 39 years.
* They are slow growing and tend to present in the 3rd to 5th decades of life.
* [[Maxillary]] and extraosseous [[ameloblastoma]] commonly affects individuals in a slightly older age group while unicystic and granular cell [[ameloblastoma]] occur in a younger age group.  
* The average age of unicystic ameloblastoma is 10.8 years.
 
=== Region ===
* The majority of [[ameloblastoma]] cases are reported in Africa, China, and India.<ref name="pmid25577151">{{cite journal |vauthors=Bzhalava D, Eklund C, Dillner J |title=International standardization and classification of human papillomavirus types |journal=Virology |volume=476 |issue= |pages=341–344 |date=February 2015 |pmid=25577151 |doi=10.1016/j.virol.2014.12.028 |url=}}</ref><ref name="pmid9868729">{{cite journal |vauthors=Lu Y, Xuan M, Takata T, Wang C, He Z, Zhou Z, Mock D, Nikai H |title=Odontogenic tumors. A demographic study of 759 cases in a Chinese population |journal=Oral Surg Oral Med Oral Pathol Oral Radiol Endod |volume=86 |issue=6 |pages=707–14 |date=December 1998 |pmid=9868729 |doi= |url=}}</ref>
 
 


==References==
==References==

Latest revision as of 18:40, 23 October 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2], Vamsikrishna Gunnam M.B.B.S [3]

Overview

The incidence of ameloblastoma is approximately 1.96, 1.20, 0.18, and 0.44 per 100,000 for black males, black females, white males, and white females respectively, worldwide. Ameloblastoma affects men and women equally. There is no racial predilection to the ameloblastoma. Ameloblastoma usually occur in middle age group i.e. 20-40 years; the median age at diagnosis is 39 years.

Epidemiology and Demographics

Incidence

Gender

  • Ameloblastoma affects men and women almost equally. Although, women tend to be 4 years younger than men when tumors first occur and tumors appear to be larger in females.[2]
  • The male to female ratio is approximately 1.2:1.[3]

Race

  • There is no racial predilection to the ameloblastoma. However, there is conflicting evidence on the incidence rates in different races.
  • Although some reports claim an increased incidence of ameloblastoma in black individuals, a large study identifies Asians as the population with greatest number of affected patients.
  • Ameloblastoma is by far the most common unequivocal odontogenic neoplasm in all ethnic groups, representing approximately 1% of head and neck neoplasms in Europe and the USA, some studies claim that it has the highest incidence in Afro-Caribbean populations.[4]

Age

  • Ameloblastoma commonly affects adults than younger people, the median age at diagnosis is 39 years.
  • They are slow growing and tend to present in the 3rd to 5th decades of life.
  • Maxillary and extraosseous ameloblastoma commonly affects individuals in a slightly older age group while unicystic and granular cell ameloblastoma occur in a younger age group.
  • The average age of unicystic ameloblastoma is 10.8 years.

Region


References

  1. Kreppel, M; Zöller, J (2018). "Ameloblastoma-Clinical, radiological, and therapeutic findings". Oral Diseases. 24 (1–2): 63–66. doi:10.1111/odi.12702. ISSN 1354-523X.
  2. Toledo-Pereyra LH, Bergren CT (1987). "Liver preservation techniques for transplantation". Artif Organs. 11 (3): 214–23. PMID 3304226.
  3. Kreppel, M; Zöller, J (2018). "Ameloblastoma-Clinical, radiological, and therapeutic findings". Oral Diseases. 24 (1–2): 63–66. doi:10.1111/odi.12702. ISSN 1354-523X.
  4. Morgan, Peter R. (2011). "Odontogenic tumors: a review". Periodontology 2000. 57 (1): 160–176. doi:10.1111/j.1600-0757.2011.00393.x. ISSN 0906-6713.
  5. Bzhalava D, Eklund C, Dillner J (February 2015). "International standardization and classification of human papillomavirus types". Virology. 476: 341–344. doi:10.1016/j.virol.2014.12.028. PMID 25577151.
  6. Lu Y, Xuan M, Takata T, Wang C, He Z, Zhou Z, Mock D, Nikai H (December 1998). "Odontogenic tumors. A demographic study of 759 cases in a Chinese population". Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 86 (6): 707–14. PMID 9868729.

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