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{{Plummer-Vinson syndrome}}
{{Plummer-Vinson syndrome}}
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==Overview==
==Overview==
Obtaining a [[History and Physical examination|history]] gives important information in making a [[diagnosis]] of Plummer-Vinson syndrome. Complete history should be obtained regarding onset, duration, and progression of [[symptoms]] such as [[dysphagia]] (solids or liquids), [[weakness]], [[fatigue]], [[dyspnea]], and history of [[choking]] spells or [[aspiration]]. The common symptoms of Plummer-Vinson syndrome are difficulty in [[swallowing]] (more for [[solids]]), burning sensation in [[mouth]], dry [[tongue]] and [[Pale skin color|pale color of the skin]]. Less common symptoms include cold intolerance, reduced resistance to [[infection]] and craving for for unusual items (such as [[ice]] or cold vegetables).


==History==  
==History==  
===History===
===History===
Obtaining a [[History and Physical examination|history]] gives important information in making a [[diagnosis]] of Plummer-Vinson syndrome. It provides an insight into the cause, precipitating factors, and associated [[comorbid]] conditions. A complete [[History and Physical examination|history]] will help determine the correct [[therapy]] and helps in determining the [[prognosis]]. The areas of focus should be on onset, duration, and progression of [[symptoms]] such as:
Obtaining [[History and Physical examination|history]] gives important information in making a [[diagnosis]] of Plummer-Vinson syndrome. It provides an insight into the cause, precipitating factors, and associated [[comorbid]] conditions. A complete [[History and Physical examination|history]] will help determine the correct [[therapy]] and helps in determining the [[prognosis]]. The areas of focus should be on onset, duration, and progression of [[symptoms]] such as:<ref name="pmid7575056">{{cite journal |vauthors=Hoffman RM, Jaffe PE |title=Plummer-Vinson syndrome. A case report and literature review |journal=Arch. Intern. Med. |volume=155 |issue=18 |pages=2008–11 |year=1995 |pmid=7575056 |doi= |url=}}</ref><ref name="pmid10505167">{{cite journal |vauthors=Mansell NJ, Jani P, Bailey CM |title=Plummer-Vinson syndrome--a rare presentation in a child |journal=J Laryngol Otol |volume=113 |issue=5 |pages=475–6 |year=1999 |pmid=10505167 |doi= |url=}}</ref><ref name="pmid10549778">{{cite journal |vauthors=Anthony R, Sood S, Strachan DR, Fenwick JD |title=A case of Plummer-Vinson syndrome in childhood |journal=J. Pediatr. Surg. |volume=34 |issue=10 |pages=1570–2 |year=1999 |pmid=10549778 |doi= |url=}}</ref>
*[[Dysphagia]] (solids or liquids)  
*[[Dysphagia]] (solids or liquids)  
*Weakness and fatigue
*[[Weakness]] and [[fatigue]]
*Dyspnea  
*[[Dyspnea]]
*Weight loss  
*[[Weight loss]]
*Any history of choking spells or aspiration  
*Any history of [[choking]] spells or [[aspiration]]
*Any history of bleeding disorders  
*Any history of [[bleeding disorders]]


==Symptoms==
==Symptoms==
===Common Symptoms===
===Common Symptoms===
* [[Dysphagia]] (more for solids)
Common symptoms of  Plummer-Vinson syndrome include:<ref name="pmid11753173">{{cite journal |vauthors=López Rodríguez MJ, Robledo Andrés P, Amarilla Jiménez A, Roncero Maíllo M, López Lafuente A, Arroyo Carrera I |title=Sideropenic dysphagia in an adolescent |journal=J. Pediatr. Gastroenterol. Nutr. |volume=34 |issue=1 |pages=87–90 |year=2002 |pmid=11753173 |doi= |url=}}</ref><ref name="pmid4449772">{{cite journal |vauthors=Chisholm M |title=The association between webs, iron and post-cricoid carcinoma |journal=Postgrad Med J |volume=50 |issue=582 |pages=215–9 |year=1974 |pmid=4449772 |pmc=2495558 |doi= |url=}}</ref><ref name="pmid1192404">{{cite journal |vauthors=Larsson LG, Sandström A, Westling P |title=Relationship of Plummer-Vinson disease to cancer of the upper alimentary tract in Sweden |journal=Cancer Res. |volume=35 |issue=11 Pt. 2 |pages=3308–16 |year=1975 |pmid=1192404 |doi= |url=}}</ref><ref name="pmid16978405">{{cite journal |author=Novacek G |title=Plummer-Vinson syndrome |journal=Orphanet J Rare Dis |volume=1 |issue= |pages=36 |year=2006 |pmid=16978405 |doi=10.1186/1750-1172-1-36 |url=http://www.ojrd.com/content/1//36}}</ref>
 
* [[Difficulty swallowing]] (more for solids)
* [[Weakness]]
* [[Weakness]]
* [[Pain]]
* [[Pain]]
* Burning sensation in mouth
* Burning sensation in mouth
* Dry tongue
* Dry [[tongue]]
* Painful cracks in the angles of a dry mouth
* [[Chelitis|Painful cracks in the angles of a dry mouth]]
* Pale color of the skin
* [[Pallor|Pale color of the skin]]


===Less Common Symptoms===
===Less Common Symptoms===
*Cold intolerance
*Cold intolerance
*Reduced resistance to infection
*Reduced resistance to [[infection]]
*Altered behavior  
*Altered behavior  
*Craving for for unusual items (such as ice or cold vegetables)
*Craving for for unusual items (such as [[ice]] or cold vegetables)


==References==
==References==

Latest revision as of 18:15, 24 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]

Overview

Obtaining a history gives important information in making a diagnosis of Plummer-Vinson syndrome. Complete history should be obtained regarding onset, duration, and progression of symptoms such as dysphagia (solids or liquids), weakness, fatigue, dyspnea, and history of choking spells or aspiration. The common symptoms of Plummer-Vinson syndrome are difficulty in swallowing (more for solids), burning sensation in mouth, dry tongue and pale color of the skin. Less common symptoms include cold intolerance, reduced resistance to infection and craving for for unusual items (such as ice or cold vegetables).

History

History

Obtaining history gives important information in making a diagnosis of Plummer-Vinson syndrome. It provides an insight into the cause, precipitating factors, and associated comorbid conditions. A complete history will help determine the correct therapy and helps in determining the prognosis. The areas of focus should be on onset, duration, and progression of symptoms such as:[1][2][3]

Symptoms

Common Symptoms

Common symptoms of Plummer-Vinson syndrome include:[4][5][6][7]

Less Common Symptoms

  • Cold intolerance
  • Reduced resistance to infection
  • Altered behavior
  • Craving for for unusual items (such as ice or cold vegetables)

References

  1. Hoffman RM, Jaffe PE (1995). "Plummer-Vinson syndrome. A case report and literature review". Arch. Intern. Med. 155 (18): 2008–11. PMID 7575056.
  2. Mansell NJ, Jani P, Bailey CM (1999). "Plummer-Vinson syndrome--a rare presentation in a child". J Laryngol Otol. 113 (5): 475–6. PMID 10505167.
  3. Anthony R, Sood S, Strachan DR, Fenwick JD (1999). "A case of Plummer-Vinson syndrome in childhood". J. Pediatr. Surg. 34 (10): 1570–2. PMID 10549778.
  4. López Rodríguez MJ, Robledo Andrés P, Amarilla Jiménez A, Roncero Maíllo M, López Lafuente A, Arroyo Carrera I (2002). "Sideropenic dysphagia in an adolescent". J. Pediatr. Gastroenterol. Nutr. 34 (1): 87–90. PMID 11753173.
  5. Chisholm M (1974). "The association between webs, iron and post-cricoid carcinoma". Postgrad Med J. 50 (582): 215–9. PMC 2495558. PMID 4449772.
  6. Larsson LG, Sandström A, Westling P (1975). "Relationship of Plummer-Vinson disease to cancer of the upper alimentary tract in Sweden". Cancer Res. 35 (11 Pt. 2): 3308–16. PMID 1192404.
  7. Novacek G (2006). "Plummer-Vinson syndrome". Orphanet J Rare Dis. 1: 36. doi:10.1186/1750-1172-1-36. PMID 16978405.