Stomach cancer endoscopy and biopsy: Difference between revisions
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==Overview== | ==Overview== | ||
[[Biopsy]] may be helpful in the diagnosis of stomach cancer. It has a [[Sensitivity (tests)|sensitivity]] of 98% to diagnose gastric cancer but may be negative in [[linitis plastica]]. It is commonly used nowadays as first line of treatment for superficial lesions. | [[Biopsy]] may be helpful in the [[diagnosis]] of [[stomach cancer]]. It has a [[Sensitivity (tests)|sensitivity]] of 98% to [[diagnose]] [[gastric cancer]] but may be negative in [[linitis plastica]]. It is commonly used nowadays as first line of treatment for [[superficial]] [[lesions]]. | ||
==Endoscopy and Biopsy== | ==Endoscopy and Biopsy== | ||
* The diagnosis of early lesions appears to be increasing since [[Upper endoscopy|upper gastrointestinal endoscopy]] became widely used. | * The [[diagnosis]] of early [[lesions]] appears to be increasing since [[Upper endoscopy|upper gastrointestinal endoscopy]] became widely used. | ||
* Obtaining seven biopsies from the ulcer margin and base have a [[Sensitivity (tests)|sensitivity]] of 98% to diagnose gastric cancer.<ref name="pmid7054024">{{cite journal| author=Graham DY, Schwartz JT, Cain GD, Gyorkey F| title=Prospective evaluation of biopsy number in the diagnosis of esophageal and gastric carcinoma. | journal=Gastroenterology | year= 1982 | volume= 82 | issue= 2 | pages= 228-31 | pmid=7054024 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7054024 }}</ref> | * Obtaining seven [[biopsies]] from the [[ulcer]] margin and base have a [[Sensitivity (tests)|sensitivity]] of 98% to [[diagnose]] [[gastric cancer]].<ref name="pmid7054024">{{cite journal| author=Graham DY, Schwartz JT, Cain GD, Gyorkey F| title=Prospective evaluation of biopsy number in the diagnosis of esophageal and gastric carcinoma. | journal=Gastroenterology | year= 1982 | volume= 82 | issue= 2 | pages= 228-31 | pmid=7054024 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7054024 }}</ref> | ||
* It may be | * It may be [[false negative]] in [[Linitis plastica|linitis plastica cancers]].<ref name="pmid7859977">{{cite journal| author=Karita M, Tada M| title=Endoscopic and histologic diagnosis of submucosal tumors of the gastrointestinal tract using combined strip biopsy and bite biopsy. | journal=Gastrointest Endosc | year= 1994 | volume= 40 | issue= 6 | pages= 749-53 | pmid=7859977 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7859977 }}</ref> | ||
* | * The European guidelines recommend [[endoscopic]] [[resection]] as a [[first-line treatment]] for [[superficial]] [[neoplastic]] [[gastric]] [[lesions]].<ref name="pmid26317585">{{cite journal| author=Pimentel-Nunes P, Dinis-Ribeiro M, Ponchon T, Repici A, Vieth M, De Ceglie A et al.| title=Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. | journal=Endoscopy | year= 2015 | volume= 47 | issue= 9 | pages= 829-54 | pmid=26317585 | doi=10.1055/s-0034-1392882 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26317585 }}</ref> | ||
[[File:Por-sig.jpg|300px|center|thumb|Endoscopy shows gastric cancer, source: By Med Chaos - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=15690680]] | [[File:Por-sig.jpg|300px|center|thumb|Endoscopy shows gastric cancer, source: By Med Chaos - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=15690680]] | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Gastroenterology]] | |||
[[Category:Surgery]] | |||
Latest revision as of 17:13, 23 May 2019
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Stomach cancer endoscopy and biopsy On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
Biopsy may be helpful in the diagnosis of stomach cancer. It has a sensitivity of 98% to diagnose gastric cancer but may be negative in linitis plastica. It is commonly used nowadays as first line of treatment for superficial lesions.
Endoscopy and Biopsy
- The diagnosis of early lesions appears to be increasing since upper gastrointestinal endoscopy became widely used.
- Obtaining seven biopsies from the ulcer margin and base have a sensitivity of 98% to diagnose gastric cancer.[1]
- It may be false negative in linitis plastica cancers.[2]
- The European guidelines recommend endoscopic resection as a first-line treatment for superficial neoplastic gastric lesions.[3]
References
- ↑ Graham DY, Schwartz JT, Cain GD, Gyorkey F (1982). "Prospective evaluation of biopsy number in the diagnosis of esophageal and gastric carcinoma". Gastroenterology. 82 (2): 228–31. PMID 7054024.
- ↑ Karita M, Tada M (1994). "Endoscopic and histologic diagnosis of submucosal tumors of the gastrointestinal tract using combined strip biopsy and bite biopsy". Gastrointest Endosc. 40 (6): 749–53. PMID 7859977.
- ↑ Pimentel-Nunes P, Dinis-Ribeiro M, Ponchon T, Repici A, Vieth M, De Ceglie A; et al. (2015). "Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline". Endoscopy. 47 (9): 829–54. doi:10.1055/s-0034-1392882. PMID 26317585.