Osteosarcoma laboratory findings: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Osteosarcoma}} | {{Osteosarcoma}} | ||
{{CMG}};{{AE}} | {{CMG}}; {{AE}}[[User:DrMars|Mohammadmain Rezazadehsaatlou[2]]]. | ||
==Overview== | ==Overview== | ||
Laboratory tests for osteosarcoma include complete blood count (CBC), serum [[alkaline phosphatase]] and [[lactate dehydrogenase]]. | Laboratory tests for [[osteosarcoma]] include [[complete blood count]] ([[Complete blood count|CBC]]), serum [[alkaline phosphatase]] and [[lactate dehydrogenase]]. | ||
==Laboratory Tests== | ==Laboratory Tests== | ||
Laboratory tests for osteosarcoma include the following: | Laboratory tests for [[osteosarcoma]] include the following:<ref name="pmid19915470">{{cite journal |vauthors=Kim HJ, Chalmers PN, Morris CD |title=Pediatric osteogenic sarcoma |journal=Curr. Opin. Pediatr. |volume=22 |issue=1 |pages=61–6 |date=February 2010 |pmid=19915470 |doi=10.1097/MOP.0b013e328334581f |url=}}</ref><ref name="pmid25070231">{{cite journal |vauthors=Moore DD, Luu HH |title=Osteosarcoma |journal=Cancer Treat. Res. |volume=162 |issue= |pages=65–92 |date=2014 |pmid=25070231 |doi=10.1007/978-3-319-07323-1_4 |url=}}</ref><ref name="pmid20179183">{{cite journal |vauthors=Ilaslan H, Schils J, Nageotte W, Lietman SA, Sundaram M |title=Clinical presentation and imaging of bone and soft-tissue sarcomas |journal=Cleve Clin J Med |volume=77 Suppl 1 |issue= |pages=S2–7 |date=March 2010 |pmid=20179183 |doi=10.3949/ccjm.77.s1.01 |url=}}</ref><ref name="pmid21037356">{{cite journal |vauthors=Wu PK, Chen WM, Lee OK, Chen CF, Huang CK, Chen TH |title=The prognosis for patients with osteosarcoma who have received prior manipulative therapy |journal=J Bone Joint Surg Br |volume=92 |issue=11 |pages=1580–5 |date=November 2010 |pmid=21037356 |doi=10.1302/0301-620X.92B11.24706 |url=}}</ref><ref name="pmid29980176">{{cite journal |vauthors=Obiedat H, Alrabadi N, Sultan E, Al Shatti M, Zihlif M |title=The effect of ERCC1 and ERCC2 gene polymorphysims on response to cisplatin based therapy in osteosarcoma patients |journal=BMC Med. Genet. |volume=19 |issue=1 |pages=112 |date=July 2018 |pmid=29980176 |pmc=6035436 |doi=10.1186/s12881-018-0627-4 |url=}}</ref> | ||
*Complete blood count | |||
*[[Complete blood count]] ([[Complete blood count|CBC]]), including differential | |||
*[[Platelet count]] | |||
*[[Liver function tests]]: | |||
**[[Aspartate aminotransferase]] ([[Aspartate transaminase|AST]]) | |||
**[[Alanine aminotransferase]] ([[Alanine transaminase|ALT]]) | |||
**[[Bilirubin]] | |||
**[[Albumins|Albumin]] | |||
*[[Electrolyte]] levels - [[Sodium]], [[potassium]], [[chloride]], [[bicarbonate]], [[calcium]], [[magnesium]], [[phosphorus]] | |||
*[[Renal function tests]] - [[Blood urea nitrogen]]([[Blood urea nitrogen|BUN]]), [[creatinine]] | |||
*[[Urinalysis]] | |||
*Blood chemistry studies include: | *Blood chemistry studies include: | ||
**[[Serum]] [[alkaline phosphatase]]. | |||
**[[Lactate dehydrogenase]]. | |||
==References== | ==References== | ||
Latest revision as of 18:43, 19 October 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2].
Overview
Laboratory tests for osteosarcoma include complete blood count (CBC), serum alkaline phosphatase and lactate dehydrogenase.
Laboratory Tests
Laboratory tests for osteosarcoma include the following:[1][2][3][4][5]
- Complete blood count (CBC), including differential
- Platelet count
- Liver function tests:
- Electrolyte levels - Sodium, potassium, chloride, bicarbonate, calcium, magnesium, phosphorus
- Renal function tests - Blood urea nitrogen(BUN), creatinine
- Urinalysis
- Blood chemistry studies include:
References
- ↑ Kim HJ, Chalmers PN, Morris CD (February 2010). "Pediatric osteogenic sarcoma". Curr. Opin. Pediatr. 22 (1): 61–6. doi:10.1097/MOP.0b013e328334581f. PMID 19915470.
- ↑ Moore DD, Luu HH (2014). "Osteosarcoma". Cancer Treat. Res. 162: 65–92. doi:10.1007/978-3-319-07323-1_4. PMID 25070231.
- ↑ Ilaslan H, Schils J, Nageotte W, Lietman SA, Sundaram M (March 2010). "Clinical presentation and imaging of bone and soft-tissue sarcomas". Cleve Clin J Med. 77 Suppl 1: S2–7. doi:10.3949/ccjm.77.s1.01. PMID 20179183.
- ↑ Wu PK, Chen WM, Lee OK, Chen CF, Huang CK, Chen TH (November 2010). "The prognosis for patients with osteosarcoma who have received prior manipulative therapy". J Bone Joint Surg Br. 92 (11): 1580–5. doi:10.1302/0301-620X.92B11.24706. PMID 21037356.
- ↑ Obiedat H, Alrabadi N, Sultan E, Al Shatti M, Zihlif M (July 2018). "The effect of ERCC1 and ERCC2 gene polymorphysims on response to cisplatin based therapy in osteosarcoma patients". BMC Med. Genet. 19 (1): 112. doi:10.1186/s12881-018-0627-4. PMC 6035436. PMID 29980176.