Thyroid adenoma laboratory findings: Difference between revisions

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Latest revision as of 14:25, 1 May 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Laboratory findings consistent with the diagnosis of thyroid adenoma include decreased thyroid stimulating hormone, elevated calcitonin, and decreased calcium.

Laboratory Findings

Blood or imaging tests may be done prior to or in lieu of a biopsy. The following blood tests are conducted:^[1]

Thyroid stimulating hormone (TSH)
Thyroid hormones thyroxine (T4)
Triiodothyronine (T3)

Tests for serum thyroid autoantibodies are sometimes done to rule out autoimmune thyroid disease (which can mimic nodular disease).
Laboratory findings consistent with the diagnosis of multiple endocrine neoplasia type 2:
- Decreased thyroid stimulating hormone
- Antithyroid antibodies
- Elevated calcitonin
- Decreased calcium
- Antithyroid antibodies
- Serum calcitonin

Adapted from Arzu Tatlıpınar1 and İlkay Kartal [Updated 2015].The Evaluation of Thyroid Nodules. Journal of Thyroid Disorders & Therapy.2015.^[2]

Laboratory tests	Normal Range	Abnormal value
Serum
Thyroid stimulating hormone	0.4 - 4.0 milli-international units per liter	<0.4 or >4.0
Antithyroid antibodies	<35 IU/mL	>35 IU/mL
Serum calcitonin	less than 10pg/mL	>=100 pg/mL

References

↑ Bomeli SR, LeBeau SO, Ferris RL (April 2010). "Evaluation of a thyroid nodule". Otolaryngol. Clin. North Am. 43 (2): 229–38, vii. doi:10.1016/j.otc.2010.01.002. PMC 2879398. PMID 20510711.
↑ İlkay Kartal, Arzu Tatlıpınar (2014). "The Evaluation of Thyroid Nodules". Journal of Thyroid Disorders and Therapy. 04 (02). doi:10.4172/2167-7948.1000181. ISSN 2167-7948.

Template:WH Template:WS

[pmid20510711-1] Bomeli SR, LeBeau SO, Ferris RL (April 2010). "Evaluation of a thyroid nodule". Otolaryngol. Clin. North Am. 43 (2): 229–38, vii. doi:10.1016/j.otc.2010.01.002. PMC 2879398. PMID 20510711.

[İlkay_Kartal2014-2] İlkay Kartal, Arzu Tatlıpınar (2014). "The Evaluation of Thyroid Nodules". Journal of Thyroid Disorders and Therapy. 04 (02). doi:10.4172/2167-7948.1000181. ISSN 2167-7948.

[1]

[2]

@@ Line 3: / Line 3: @@
 {{CMG}}; {{AE}} {{Ammu}}
 ==Overview==
-Laboratory findings consistent with the diagnosis of thyroid adenoma include decreased [[thyroid stimulating hormone]], elevated [[calcitonin]], and [[hypocalcemia|decreased calcium]].
+Laboratory findings consistent with the diagnosis of thyroid [[adenoma]] include decreased [[thyroid stimulating hormone]], elevated [[calcitonin]], and [[hypocalcemia|decreased calcium]].
 ==Laboratory Findings==
-* [[Blood]] or imaging tests may be done prior to or in lieu of a biopsy. The following blood tests are conducted:
+* [[Blood]] or imaging tests may be done prior to or in lieu of a biopsy. The following blood tests are conducted:<ref name="pmid20510711">{{cite journal |vauthors=Bomeli SR, LeBeau SO, Ferris RL |title=Evaluation of a thyroid nodule |journal=Otolaryngol. Clin. North Am. |volume=43 |issue=2 |pages=229–38, vii |date=April 2010 |pmid=20510711 |pmc=2879398 |doi=10.1016/j.otc.2010.01.002 |url=}}</ref>
 :* [[Thyroid stimulating hormone]] (TSH)
 :* Thyroid hormones [[thyroxine]] (T4)
 :* [[Triiodothyronine]] (T3)
 * Tests for serum thyroid [[antibodies|autoantibodies]] are sometimes done to rule out [[autoimmune]] thyroid disease (which can mimic nodular disease).
-* Laboratory findings consistent with the diagnosis of multiple endocrine neoplasia type 2 are tabulated below.
+* Laboratory findings consistent with the diagnosis of [[multiple endocrine neoplasia type 2]]:
-{| style="border: 2px solid #B8B8B8; font-size: 90%; width: 30%;"
+** Decreased [[thyroid stimulating hormone]]
-|+ '''Laboratory findings'''
+** Antithyroid antibodies
-|-
+** Elevated [[calcitonin]]
-! style="width: 75px; background: #4479BA; text-align: center;"|{{fontcolor|#FFF|Test}}
+** Decreased [[calcium]]
-! style="width: 200px; background: #4479BA; text-align: center;"| {{fontcolor|#FFF|Findings}}
+** Antithyroid antibodies
-|-
+** Serum [[calcitonin]]
-| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Metabolic]]'''
-| style="background: #B8B8B8; padding: 5px;"|Decreased [[thyroid stimulating hormone]]<br>Antithyroid antibodies<br>Elevated [[calcitonin]]<br>Decreased calcium
+Adapted from Arzu Tatlıpınar1 and İlkay Kartal [Updated 2015].The Evaluation of Thyroid Nodules. ''Journal of Thyroid Disorders & Therapy''.2015.<ref name="İlkay Kartal2014">{{cite journal|last1=İlkay Kartal|first1=Arzu Tatlıpınar|title=The Evaluation of Thyroid Nodules|journal=Journal of Thyroid Disorders and Therapy|volume=04|issue=02|year=2014|issn=21677948|doi=10.4172/2167-7948.1000181}}</ref>
-|-
-| style="padding: 5px 5px; background: #F5F5F5;" colspan="2"|<small>Adapted from Arzu Tatlıpınar1 and İlkay Kartal [Updated 2015].The Evaluation of Thyroid Nodules. ''Journal of Thyroid Disorders & Therapy''.2015.<ref name="İlkay Kartal2014">{{cite journal|last1=İlkay Kartal|first1=Arzu Tatlıpınar|title=The Evaluation of Thyroid Nodules|journal=Journal of Thyroid Disorders and Therapy|volume=04|issue=02|year=2014|issn=21677948|doi=10.4172/2167-7948.1000181}}</ref><small>
-|}
 {|
 |-
-| valign=top |
+| valign="top" |
-{|style="border: 0px; font-size: 90%; margin: 3px; width: 700px;" align=center
+{| style="border: 0px; font-size: 90%; margin: 3px; width: 700px;" align="center"
-! style="padding: 0 5px; background: #4479BA" align=center |{{fontcolor|#FFF| Laboratory tests}}
+! style="padding: 0 5px; background: #4479BA" align="center" |{{fontcolor|#FFF| Laboratory tests}}
-! style="background:#4479BA;" align=center|{{fontcolor|#FFF| Normal Range}}
+! style="background:#4479BA;" align="center" |{{fontcolor|#FFF| Normal Range}}
-! style="background:#4479BA; width: 300px" align=center|{{fontcolor|#FFF| Abnormal value}}
+! style="background:#4479BA; width: 300px" align="center" |{{fontcolor|#FFF| Abnormal value}}
 |-
-| style="padding: 0 5px; background: #4479BA" colspan=3 |{{fontcolor|#FFF| Serum}}
+| colspan="3" style="padding: 0 5px; background: #4479BA" |{{fontcolor|#FFF| Serum}}
 |-
-! style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align=left|Thyroid stimulating hormone
+! style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align="left" |Thyroid stimulating hormone
-| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align=left| 0.4 - 4.0 milli-international units per liter
+| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align="left" | 0.4 - 4.0 milli-international units per liter
-| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align=left| <0.4 or >4.0
+| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align="left" | <0.4 or >4.0
 |-
-! style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align=left|Antithyroid antibodies
+! style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align="left" |Antithyroid antibodies
-| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align=left|<35 IU/mL
+| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align="left" |<35 IU/mL
-| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align=left|>35 IU/mL
+| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align="left" |>35 IU/mL
 |-
-! style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align=left|Serum [[calcitonin]]
+! style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align="left" |Serum [[calcitonin]]
-| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align=left|less than 10pg/mL
+| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align="left" |less than 10pg/mL
-| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align=left|>=100 pg/mL
+| style="padding: 0 5px; font-size: 100%; background: #f0f0f0" align="left" |>=100 pg/mL
 |}
-{{Familytree/start}}
-{{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | | | | | | A01 | | | | | | | | | | | | | | | | | | |A01= A patient with thyroid nodule}}
-{{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | |,|-|-|-|-|^|-|-|-|-|.| | | | | | | | | | | | | | | | | | |}}
-{{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | B01 | | | | | | | | B02 | | | | | | | | | | | | | | | |B01= Normal [[thyroid stimulating hormone]]|B02= Low [[thyroid stimulating hormone]]|}}
-{{Familytree|boxstyle=background: #E0FFFF;| | | | | | |,|-|-|^|-|.| | | | | | | |!| | | | | | | | | | | | | | |}}
-{{Familytree|boxstyle=background: #E0FFFF;| | | | | | C01 | | | C02 | | | | | | C03 | | | | | | | | | | | | | | | | | |C01= <1cm suspicious nodule|C02= >1cm nodule|C03=Thyroid nuclear scan}}
-{{Familytree|boxstyle=background: #E0FFFF;| | | | | | |!| | | | |!| | | | |,|-|-|^|-|-|-|.| | | | | | | | | | | | | | | | | | | |}}
-{{Familytree|boxstyle=background: #E0FFFF;| | | | | | D01 | | | D02 | | | | D03 | | | | D04 | | | | | | | | | | | | | | |D01= Ultrasound guided fine needle aspiration cytology|D02= Fine needle aspiration cytology|D03= Hot nodule|D04= Cold nodule}}{{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | | | | | | | | | | | | | | | |!| | | | | | | | | | | |}}
-{{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | | | | | | | | | | | | | | | E05 | | | | | | | | | | | |E05= Fine needle aspiration cytology}}
-{{Familytree/end}}
 ==References==
@@ Line 67: / Line 53: @@
 [[Category:Endocrinology]]
 [[Category:Surgery]]
+|}

Thyroid adenoma laboratory findings: Difference between revisions

Latest revision as of 14:25, 1 May 2019

Overview

Laboratory Findings

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