Hemochromatosis electrocardiogram: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Hemochromatosis}} | {{Hemochromatosis}} | ||
{{CMG}}; {{AE}}{{SKA}} | {{CMG}} {{shyam}}; {{AE}}{{SKA}} | ||
==Overview== | ==Overview== | ||
Hemochromatosis can lead to deposition of iron in heart and damage its myocardial tissue as well as conduction tissue. It will cause cardiomyopathy and cardiac arrhythmia. | Hemochromatosis can lead to deposition of iron in the heart and damage its myocardial tissue as well as conduction tissue. It will cause cardiomyopathy and cardiac arrhythmia. | ||
==Electrocardiogram== | ==Electrocardiogram== | ||
EKG could be done to evaluate cardiac arrhythmia in patients of | EKG could be done to evaluate cardiac arrhythmia in patients of hemochromatosis.<ref name="pmid18424348">{{cite journal| author=Fowler C| title=Hereditary hemochromatosis: pathophysiology, diagnosis, and management. | journal=Crit Care Nurs Clin North Am | year= 2008 | volume= 20 | issue= 2 | pages= 191-201, vi | pmid=18424348 | doi=10.1016/j.ccell.2008.01.003 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18424348 }}</ref> | ||
* However cardiac arrhythmia marginally increased in asymptomatic subjects with hemochromatosis.<ref name="pmid22196777">{{cite journal| author=Shizukuda Y, Tripodi DJ, Zalos G, Bolan CD, Yau YY, Leitman SF et al.| title=Incidence of cardiac arrhythmias in asymptomatic hereditary hemochromatosis subjects with C282Y homozygosity. | journal=Am J Cardiol | year= 2012 | volume= 109 | issue= 6 | pages= 856-60 | pmid=22196777 | doi=10.1016/j.amjcard.2011.11.011 | pmc=3294140 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22196777 }}</ref> | * However cardiac arrhythmia marginally increased in asymptomatic subjects with hemochromatosis.<ref name="pmid22196777">{{cite journal| author=Shizukuda Y, Tripodi DJ, Zalos G, Bolan CD, Yau YY, Leitman SF et al.| title=Incidence of cardiac arrhythmias in asymptomatic hereditary hemochromatosis subjects with C282Y homozygosity. | journal=Am J Cardiol | year= 2012 | volume= 109 | issue= 6 | pages= 856-60 | pmid=22196777 | doi=10.1016/j.amjcard.2011.11.011 | pmc=3294140 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22196777 }}</ref> | ||
* | * The incidence of ventricular and supraventricular ectopy tends to be greater in the combined heterozygous form of hemochromatosis. | ||
* 31% of patients have ST segment and T wave abnormalities and supraventricular arrhythmias. | * 31% of patients have ST segment and T wave abnormalities and supraventricular arrhythmias. | ||
* Some patients will have low-voltage QRS complexes, which is a suggestive feature of iron infiltration and impaired electrical conduction in the cardiac tissue. | |||
==References== | ==References== | ||
Latest revision as of 18:20, 1 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Sunny Kumar MD [3]
Overview
Hemochromatosis can lead to deposition of iron in the heart and damage its myocardial tissue as well as conduction tissue. It will cause cardiomyopathy and cardiac arrhythmia.
Electrocardiogram
EKG could be done to evaluate cardiac arrhythmia in patients of hemochromatosis.[1]
- However cardiac arrhythmia marginally increased in asymptomatic subjects with hemochromatosis.[2]
- The incidence of ventricular and supraventricular ectopy tends to be greater in the combined heterozygous form of hemochromatosis.
- 31% of patients have ST segment and T wave abnormalities and supraventricular arrhythmias.
- Some patients will have low-voltage QRS complexes, which is a suggestive feature of iron infiltration and impaired electrical conduction in the cardiac tissue.
References
- ↑ Fowler C (2008). "Hereditary hemochromatosis: pathophysiology, diagnosis, and management". Crit Care Nurs Clin North Am. 20 (2): 191–201, vi. doi:10.1016/j.ccell.2008.01.003. PMID 18424348.
- ↑ Shizukuda Y, Tripodi DJ, Zalos G, Bolan CD, Yau YY, Leitman SF; et al. (2012). "Incidence of cardiac arrhythmias in asymptomatic hereditary hemochromatosis subjects with C282Y homozygosity". Am J Cardiol. 109 (6): 856–60. doi:10.1016/j.amjcard.2011.11.011. PMC 3294140. PMID 22196777.