Gallstone disease ultrasound: Difference between revisions
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==Overview== | ==Overview== | ||
Generally [[Ultrasound|transabdominal ultrasound]] (TAUS) is considered to be the most useful test to detect gallstones. TAUS is noninvasive, readily available, low cost and doesn't expose patients to [[ionizing radiation]]. The patient should fast for at least eight hours before the examination this is to ensure that the gallbladder is distended with [[bile]], which is best for visualizing stones. | Generally [[Ultrasound|transabdominal ultrasound]] (TAUS) is considered to be the most useful test to detect gallstones. TAUS is noninvasive, readily available, low cost and doesn't expose patients to [[ionizing radiation]]. The patient should fast for at least eight hours before the examination this is to ensure that the [[gallbladder]] is distended with [[bile]], which is best for visualizing stones. | ||
==Transabdominal ultrasound== | |||
=== | The initial imaging study of choice in patients with suspected gallstones is a transabdominal [[ultrasound]] of the [[Right upper quadrant (abdomen)|right upper quadran<nowiki/>t]].<ref name="pmid7979854">{{cite journal |vauthors=Shea JA, Berlin JA, Escarce JJ, Clarke JR, Kinosian BP, Cabana MD, Tsai WW, Horangic N, Malet PF, Schwartz JS |title=Revised estimates of diagnostic test sensitivity and specificity in suspected biliary tract disease |journal=Arch. Intern. Med. |volume=154 |issue=22 |pages=2573–81 |year=1994 |pmid=7979854 |doi= |url=}}</ref><ref name="pmid108978">{{cite journal |vauthors=Conrad MR, Janes JO, Dietchy J |title=Significance of low level echoes within the gallbladder |journal=AJR Am J Roentgenol |volume=132 |issue=6 |pages=967–72 |year=1979 |pmid=108978 |doi=10.2214/ajr.132.6.967 |url=}}</ref><ref name="pmid981625">{{cite journal |vauthors=Leopold GR, Amberg J, Gosink BB, Mittelstaedt C |title=Gray scale ultrasonic cholecystography: a comparison with conventional radiographic techniques |journal=Radiology |volume=121 |issue=2 |pages=445–8 |year=1976 |pmid=981625 |doi=10.1148/121.2.445 |url=}}</ref> | ||
*[[Ultrasound]] may be helpful in the diagnosis of gallstones. Findings on an ultrasound suggestive of gallstones include: | |||
**'''Gallstones''' - [[Echogenicity|echogenic foci]] that cast an [[acoustic shadow]]. | |||
[[Ultrasound]] may be helpful in the diagnosis of gallstones. Findings on an ultrasound suggestive of gallstones include: | **'''Gravel''' - multiple, small [[Echogenicity|echogenic foci]] and cast [[Acoustic shadow|shadows]]. | ||
*Gallstones - echogenic foci that cast an acoustic shadow | **'''Sludge''' - microlithiasis that is [[Echogenicity|echogenic]] but doesn't cast a [[Acoustic shadow|shadow]]. | ||
*Gravel - multiple, small echogenic foci and cast shadows | *[[Type I and type II errors|False-negative]] or misleading results may be obtained if the gallbladder is completely filled with stones or if it is contracted around many stones. | ||
*Sludge - microlithiasis that is echogenic but doesn't cast a shadow | *A [[systematic review]] estimated that the [[Sensitivity (tests)|sensitivity]] was 84% and [[Specificity (tests)|specificity]] was 99%. | ||
*The [[Accuracy and precision|accuracy]] is, however, operator dependent. | |||
[[Type I and type II errors|False-negative]] or misleading results may be obtained if the gallbladder is completely filled with stones or if it is contracted around many stones. | *In patients who complain of [[Gallstone disease history and symptoms|biliary colic]] but have not shown evidence of gallstones on [[ultrasound]], the examination is usually repeated a few weeks later. | ||
A [[systematic review]] estimated that the [[Sensitivity (tests)|sensitivity]] was 84 | *If the repeated TAUS is still negative, then this patient may have sludge in the [[gallbladder]] and thereafter, invasive procedures are considered on an individual case basis. | ||
In patients who complain of [[Gallstone disease history and symptoms|biliary colic]] but have not shown evidence of gallstones on ultrasound, the examination is usually repeated a few weeks later. If the repeated TAUS is still negative then this patient may have sludge in the gallbladder and invasive procedures are considered on an individual case basis. | [[Image:gus.jpg|thumb|center|500px|Stones shown near the gallbladder neck. Case courtesy of radiopaedia.org by Dr Derek Smith, https://radiopaedia.org/cases/42795]] | ||
[[Image: | |||
===Endoscopic ultrasound=== | ===Endoscopic ultrasound=== | ||
The gallbladder can be | *The gallbladder can be visualized through an [[Endoscopy|endoscopic]] [[Ultrasound guided injections|ultrasound]] (EUS).<ref name="pmid8801211">{{cite journal |vauthors=Dahan P, Andant C, Lévy P, Amouyal P, Amouyal G, Dumont M, Erlinger S, Sauvanet A, Belghiti J, Zins M, Vilgrain V, Bernades P |title=Prospective evaluation of endoscopic ultrasonography and microscopic examination of duodenal bile in the diagnosis of cholecystolithiasis in 45 patients with normal conventional ultrasonography |journal=Gut |volume=38 |issue=2 |pages=277–81 |year=1996 |pmid=8801211 |pmc=1383037 |doi= |url=}}</ref><ref name="pmid10625791">{{cite journal |vauthors=Liu CL, Lo CM, Chan JK, Poon RT, Fan ST |title=EUS for detection of occult cholelithiasis in patients with idiopathic pancreatitis |journal=Gastrointest. Endosc. |volume=51 |issue=1 |pages=28–32 |year=2000 |pmid=10625791 |doi= |url=}}</ref> | ||
*During EUS, an [[ultrasound]] [[endoscope]] is placed at the gastric [[antrum]], which is in close proximity to the [[gallbladder]]. | |||
*This allows for [[imaging]] that is free of bowel gases or the [[liver]]. | |||
*Consequently, EUS is more [[sensitive]] than transabdominal [[ultrasound]] for the detection of gallstones in the following cases: | |||
**Obese patients | |||
**Microlithiasis | |||
**Anatomic abnormalities that limit [[gallbladder]] visualization with a conventional transabdominal [[ultrasound]]. | |||
[[Image: | [[Image:eug.jpg|thumb|center|500px|Stone shown near the gallbladder tip. Source:Journal of Pancreas<ref name="urlMorris-Stiff G, et al. Does Endoscopic Ultrasound Have Anything to Offer in the Diagnosis of Idiopathic Acute Pancreatitis?. JOP. J Pancreas (Online) 2009 Mar 9; 10(2):143-146. [Full text]">{{cite web |url=http://www.joplink.net/prev/200903/06.html |title=Morris-Stiff G, et al. Does Endoscopic Ultrasound Have Anything to Offer in the Diagnosis of Idiopathic Acute Pancreatitis?. JOP. J Pancreas (Online) 2009 Mar 9; 10(2):143-146. [Full text] |format= |work= |accessdate=}}</ref> ]] | ||
==References== | ==References== | ||
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[[Category: | |||
[[Category:Gastroenterology]] | |||
[[Category:Hepatology]] | |||
[[Category:Surgery]] | |||
[[Category:Disease]] | |||
[[Category:Radiology]] | |||
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American Roentgen Ray Society Images of Gallstone disease ultrasound |
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Risk calculators and risk factors for Gallstone disease ultrasound |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
Generally transabdominal ultrasound (TAUS) is considered to be the most useful test to detect gallstones. TAUS is noninvasive, readily available, low cost and doesn't expose patients to ionizing radiation. The patient should fast for at least eight hours before the examination this is to ensure that the gallbladder is distended with bile, which is best for visualizing stones.
Transabdominal ultrasound
The initial imaging study of choice in patients with suspected gallstones is a transabdominal ultrasound of the right upper quadrant.[1][2][3]
- Ultrasound may be helpful in the diagnosis of gallstones. Findings on an ultrasound suggestive of gallstones include:
- Gallstones - echogenic foci that cast an acoustic shadow.
- Gravel - multiple, small echogenic foci and cast shadows.
- Sludge - microlithiasis that is echogenic but doesn't cast a shadow.
- False-negative or misleading results may be obtained if the gallbladder is completely filled with stones or if it is contracted around many stones.
- A systematic review estimated that the sensitivity was 84% and specificity was 99%.
- The accuracy is, however, operator dependent.
- In patients who complain of biliary colic but have not shown evidence of gallstones on ultrasound, the examination is usually repeated a few weeks later.
- If the repeated TAUS is still negative, then this patient may have sludge in the gallbladder and thereafter, invasive procedures are considered on an individual case basis.
Endoscopic ultrasound
- The gallbladder can be visualized through an endoscopic ultrasound (EUS).[4][5]
- During EUS, an ultrasound endoscope is placed at the gastric antrum, which is in close proximity to the gallbladder.
- This allows for imaging that is free of bowel gases or the liver.
- Consequently, EUS is more sensitive than transabdominal ultrasound for the detection of gallstones in the following cases:
- Obese patients
- Microlithiasis
- Anatomic abnormalities that limit gallbladder visualization with a conventional transabdominal ultrasound.
References
- ↑ Shea JA, Berlin JA, Escarce JJ, Clarke JR, Kinosian BP, Cabana MD, Tsai WW, Horangic N, Malet PF, Schwartz JS (1994). "Revised estimates of diagnostic test sensitivity and specificity in suspected biliary tract disease". Arch. Intern. Med. 154 (22): 2573–81. PMID 7979854.
- ↑ Conrad MR, Janes JO, Dietchy J (1979). "Significance of low level echoes within the gallbladder". AJR Am J Roentgenol. 132 (6): 967–72. doi:10.2214/ajr.132.6.967. PMID 108978.
- ↑ Leopold GR, Amberg J, Gosink BB, Mittelstaedt C (1976). "Gray scale ultrasonic cholecystography: a comparison with conventional radiographic techniques". Radiology. 121 (2): 445–8. doi:10.1148/121.2.445. PMID 981625.
- ↑ Dahan P, Andant C, Lévy P, Amouyal P, Amouyal G, Dumont M, Erlinger S, Sauvanet A, Belghiti J, Zins M, Vilgrain V, Bernades P (1996). "Prospective evaluation of endoscopic ultrasonography and microscopic examination of duodenal bile in the diagnosis of cholecystolithiasis in 45 patients with normal conventional ultrasonography". Gut. 38 (2): 277–81. PMC 1383037. PMID 8801211.
- ↑ Liu CL, Lo CM, Chan JK, Poon RT, Fan ST (2000). "EUS for detection of occult cholelithiasis in patients with idiopathic pancreatitis". Gastrointest. Endosc. 51 (1): 28–32. PMID 10625791.
- ↑ "Morris-Stiff G, et al. Does Endoscopic Ultrasound Have Anything to Offer in the Diagnosis of Idiopathic Acute Pancreatitis?. JOP. J Pancreas (Online) 2009 Mar 9; 10(2):143-146. [Full text]".