TOR1AIP1: Difference between revisions

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'''Torsin-1A-interacting protein 1''' is a [[protein]] that in humans is encoded by the ''TOR1AIP1'' [[gene]].<ref name="pmid12061773">{{cite journal | vauthors = Kondo Y, Kondoh J, Hayashi D, Ban T, Takagi M, Kamei Y, Tsuji L, Kim J, Yoneda Y | title = Molecular cloning of one isotype of human lamina-associated polypeptide 1s and a topological analysis using its deletion mutants | journal = Biochem Biophys Res Commun | volume = 294 | issue = 4 | pages = 770–8 |date=Jun 2002 | pmid = 12061773 | pmc =  | doi = 10.1016/S0006-291X(02)00563-6 }}</ref><ref name="pmid15767459">{{cite journal | vauthors = Goodchild RE, Dauer WT | title = The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein | journal = J Cell Biol | volume = 168 | issue = 6 | pages = 855–62 |date=Mar 2005 | pmid = 15767459 | pmc = 2171781 | doi = 10.1083/jcb.200411026 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TOR1AIP1 torsin A interacting protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26092| accessdate = }}</ref>
'''Torsin-1A-interacting protein 1''' is a [[protein]] that in humans is encoded by the ''TOR1AIP1'' [[gene]]. <ref name="pmid12061773">{{cite journal | vauthors = Kondo Y, Kondoh J, Hayashi D, Ban T, Takagi M, Kamei Y, Tsuji L, Kim J, Yoneda Y | title = Molecular cloning of one isotype of human lamina-associated polypeptide 1s and a topological analysis using its deletion mutants | journal = Biochem Biophys Res Commun | volume = 294 | issue = 4 | pages = 770–8 |date=Jun 2002 | pmid = 12061773 | pmc =  | doi = 10.1016/S0006-291X(02)00563-6 }}</ref><ref name="pmid15767459">{{cite journal | vauthors = Goodchild RE, Dauer WT | title = The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein | journal = J Cell Biol | volume = 168 | issue = 6 | pages = 855–62 |date=Mar 2005 | pmid = 15767459 | pmc = 2171781 | doi = 10.1083/jcb.200411026 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TOR1AIP1 torsin A interacting protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26092| accessdate = }}</ref> More commonly known as [[nuclear lamina|lamina]] associated polypeptide 1 (LAP1), it is a type II [[integral membrane protein]] that resides in the inner nuclear membrane. The luminal domain of LAP1 interacts with [[Torsin A]] and is necessary for the ATPase activity of [[Torsin A]].
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Latest revision as of 21:14, 10 March 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Wikidata
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Torsin-1A-interacting protein 1 is a protein that in humans is encoded by the TOR1AIP1 gene. [1][2][3] More commonly known as lamina associated polypeptide 1 (LAP1), it is a type II integral membrane protein that resides in the inner nuclear membrane. The luminal domain of LAP1 interacts with Torsin A and is necessary for the ATPase activity of Torsin A.


References

  1. ↑ Kondo Y, Kondoh J, Hayashi D, Ban T, Takagi M, Kamei Y, Tsuji L, Kim J, Yoneda Y (Jun 2002). "Molecular cloning of one isotype of human lamina-associated polypeptide 1s and a topological analysis using its deletion mutants". Biochem Biophys Res Commun. 294 (4): 770–8. doi:10.1016/S0006-291X(02)00563-6. PMID 12061773.
  2. ↑ Goodchild RE, Dauer WT (Mar 2005). "The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein". J Cell Biol. 168 (6): 855–62. doi:10.1083/jcb.200411026. PMC 2171781. PMID 15767459.
  3. ↑ "Entrez Gene: TOR1AIP1 torsin A interacting protein 1".

Further reading



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