STS-1 (gene): Difference between revisions
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''For the 1981 spaceflight see: [[STS-1]]''{{Infobox_gene}} | ''For the 1981 spaceflight see: [[STS-1]]'' | ||
{{Infobox_gene}} | |||
'''Ubiquitin-associated and SH3 domain-containing protein B''' is a [[protein]] that in humans is encoded by the ''UBASH3B'' [[gene]].<ref name="pmid11853319">{{cite journal | vauthors = Nagase T, Kikuno R, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins | journal = DNA Res | volume = 8 | issue = 6 | pages = 319–27 |date=Feb 2002 | pmid = 11853319 | pmc = | doi =10.1093/dnares/8.6.319 }}</ref><ref name="pmid12370296">{{cite journal | vauthors = Carpino N, Kobayashi R, Zang H, Takahashi Y, Jou ST, Feng J, Nakajima H, Ihle JN | title = Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein | journal = Mol Cell Biol | volume = 22 | issue = 21 | pages = 7491–500 |date=Oct 2002 | pmid = 12370296 | pmc = 135669 | doi =10.1128/MCB.22.21.7491-7500.2002 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: STS-1 Cbl-interacting protein Sts-1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84959| accessdate = }}</ref> | '''Ubiquitin-associated and SH3 domain-containing protein B''' is a [[protein]] that in humans is encoded by the ''UBASH3B'' [[gene]].<ref name="pmid11853319">{{cite journal | vauthors = Nagase T, Kikuno R, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins | journal = DNA Res | volume = 8 | issue = 6 | pages = 319–27 |date=Feb 2002 | pmid = 11853319 | pmc = | doi =10.1093/dnares/8.6.319 }}</ref><ref name="pmid12370296">{{cite journal | vauthors = Carpino N, Kobayashi R, Zang H, Takahashi Y, Jou ST, Feng J, Nakajima H, Ihle JN | title = Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein | journal = Mol Cell Biol | volume = 22 | issue = 21 | pages = 7491–500 |date=Oct 2002 | pmid = 12370296 | pmc = 135669 | doi =10.1128/MCB.22.21.7491-7500.2002 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: STS-1 Cbl-interacting protein Sts-1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84959| accessdate = }}</ref> | ||
Latest revision as of 16:57, 13 July 2018
For the 1981 spaceflight see: STS-1
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Ubiquitin-associated and SH3 domain-containing protein B is a protein that in humans is encoded by the UBASH3B gene.[1][2][3]
This gene encodes a protein that contains a ubiquitin associated protein domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.[3]
References
- ↑ Nagase T, Kikuno R, Ohara O (Feb 2002). "Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins". DNA Res. 8 (6): 319–27. doi:10.1093/dnares/8.6.319. PMID 11853319.
- ↑ Carpino N, Kobayashi R, Zang H, Takahashi Y, Jou ST, Feng J, Nakajima H, Ihle JN (Oct 2002). "Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein". Mol Cell Biol. 22 (21): 7491–500. doi:10.1128/MCB.22.21.7491-7500.2002. PMC 135669. PMID 12370296.
- ↑ 3.0 3.1 "Entrez Gene: STS-1 Cbl-interacting protein Sts-1".
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Kowanetz K, Crosetto N, Haglund K, et al. (2004). "Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases". J. Biol. Chem. 279 (31): 32786–95. doi:10.1074/jbc.M403759200. PMID 15159412.
- Guo F, Sigua C, Bali P, et al. (2005). "Mechanistic role of heat shock protein 70 in Bcr-Abl-mediated resistance to apoptosis in human acute leukemia cells". Blood. 105 (3): 1246–55. doi:10.1182/blood-2004-05-2041. PMID 15388581.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Hoeller D, Crosetto N, Blagoev B, et al. (2006). "Regulation of ubiquitin-binding proteins by monoubiquitination". Nat. Cell Biol. 8 (2): 163–9. doi:10.1038/ncb1354. PMID 16429130.
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