KDM4D: Difference between revisions
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'''Lysine-specific demethylase 4D''' is an [[enzyme]] that in humans is encoded by the ''KDM4D'' [[gene]].<ref name="pmid15138608">{{cite journal |vauthors=Katoh M, Katoh M | title = Identification and characterization of JMJD2 family genes in silico | journal = | '''Lysine-specific demethylase 4D''' is an [[enzyme]] that in humans is encoded by the ''KDM4D'' [[gene]].<ref name="pmid15138608">{{cite journal | vauthors = Katoh M, Katoh M | title = Identification and characterization of JMJD2 family genes in silico | journal = International Journal of Oncology | volume = 24 | issue = 6 | pages = 1623–8 | date = June 2004 | pmid = 15138608 | pmc = | doi = 10.3892/ijo.25.3.759 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: JMJD2D jumonji domain containing 2D| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55693| accessdate = }}</ref> KDM4D belongs to the [[alpha-ketoglutarate-dependent hydroxylase]] superfamily. | ||
< | In 2017, messenger RNA from this gene was used in the {{w|somatic cell nuclear transfer}} experiment that produced the first two cloned primates from post-embryonic donor material.<ref>{{cite journal | vauthors = Liu Z, Cai Y, Wang Y, Nie Y, Zhang C, Xu Y, Zhang X, Lu Y, Wang Z, Poo M, Sun Q | title = Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer | journal = Cell | volume = 172 | issue = 4 | pages = 881–887.e7 | date = February 2018 | pmid = 29395327 | doi = 10.1016/j.cell.2018.01.020 }}</ref><ref>{{cite article | url = https://www.npr.org/sections/health-shots/2018/01/24/579925801/chinese-scientists-clone-monkeys-using-method-that-created-dolly-the-sheep |title = Chinese Scientists Clone Monkeys Using Method That Created Dolly The Sheep | first = Rob | last = Stein | name-list-format = vanc | journal = National Public Radio | date = 24 January 2018 | accessdate = 24 January 2018 }}</ref>. A similar experiment was carried out to increase the cloning efficiency of bovine species in 2018.<ref>{{cite journal | vauthors = Liu X, Wang Y, Gao Y, Su J, Zhang J, Xing X, Zhou C, Yao K, An Q, Zhang Y | title = H3K9 demethylase KDM4E is an epigenetic regulator for bovine embryonic development and a defective factor for nuclear reprogramming | journal = Development | volume = 145 | issue = 4 | date = February 2018 | pmid = 29453221 | doi = 10.1242/dev.158261 }}</ref> | ||
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==References== | {{wikinews|Healthy cloned monkeys born in Shanghai}} | ||
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{{reflist}} | {{reflist}} | ||
==Further reading== | == Further reading == | ||
{{refbegin | 2}} | {{refbegin | 2}} | ||
* {{cite journal | vauthors = Shin S, Janknecht R | title = Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D | journal = Biochemical and Biophysical Research Communications | volume = 359 | issue = 3 | pages = 742–6 | date = August 2007 | pmid = 17555712 | doi = 10.1016/j.bbrc.2007.05.179 }} | |||
* {{cite journal | vauthors = Whetstine JR, Nottke A, Lan F, Huarte M, Smolikov S, Chen Z, Spooner E, Li E, Zhang G, Colaiacovo M, Shi Y | title = Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases | journal = Cell | volume = 125 | issue = 3 | pages = 467–81 | date = May 2006 | pmid = 16603238 | doi = 10.1016/j.cell.2006.03.028 }} | |||
*{{cite journal | * {{cite journal | vauthors = Bonaldo MF, Lennon G, Soares MB | title = Normalization and subtraction: two approaches to facilitate gene discovery | journal = Genome Research | volume = 6 | issue = 9 | pages = 791–806 | date = September 1996 | pmid = 8889548 | doi = 10.1101/gr.6.9.791 }} | ||
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{{Portal bar|Molecular and Cellular Biology|border=no}} | {{Portal bar|Molecular and Cellular Biology|border=no}} | ||
[[Category:Human 2OG oxygenases]] | [[Category:Human 2OG oxygenases]] | ||
[[Category:EC 1.14.11]] | [[Category:EC 1.14.11]] | ||
{{gene-11-stub}} | {{gene-11-stub}} |
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Lysine-specific demethylase 4D is an enzyme that in humans is encoded by the KDM4D gene.[1][2] KDM4D belongs to the alpha-ketoglutarate-dependent hydroxylase superfamily.
In 2017, messenger RNA from this gene was used in the somatic cell nuclear transfer experiment that produced the first two cloned primates from post-embryonic donor material.[3][4]. A similar experiment was carried out to increase the cloning efficiency of bovine species in 2018.[5]
Wikinews has related news: Healthy cloned monkeys born in Shanghai |
References
- ↑ Katoh M, Katoh M (June 2004). "Identification and characterization of JMJD2 family genes in silico". International Journal of Oncology. 24 (6): 1623–8. doi:10.3892/ijo.25.3.759. PMID 15138608.
- ↑ "Entrez Gene: JMJD2D jumonji domain containing 2D".
- ↑ Liu Z, Cai Y, Wang Y, Nie Y, Zhang C, Xu Y, Zhang X, Lu Y, Wang Z, Poo M, Sun Q (February 2018). "Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer". Cell. 172 (4): 881–887.e7. doi:10.1016/j.cell.2018.01.020. PMID 29395327.
- ↑ Stein R (24 January 2018). "Chinese Scientists Clone Monkeys Using Method That Created Dolly The Sheep". National Public Radio. Retrieved 24 January 2018.
- ↑ Liu X, Wang Y, Gao Y, Su J, Zhang J, Xing X, Zhou C, Yao K, An Q, Zhang Y (February 2018). "H3K9 demethylase KDM4E is an epigenetic regulator for bovine embryonic development and a defective factor for nuclear reprogramming". Development. 145 (4). doi:10.1242/dev.158261. PMID 29453221.
Further reading
- Shin S, Janknecht R (August 2007). "Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D". Biochemical and Biophysical Research Communications. 359 (3): 742–6. doi:10.1016/j.bbrc.2007.05.179. PMID 17555712.
- Whetstine JR, Nottke A, Lan F, Huarte M, Smolikov S, Chen Z, Spooner E, Li E, Zhang G, Colaiacovo M, Shi Y (May 2006). "Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases". Cell. 125 (3): 467–81. doi:10.1016/j.cell.2006.03.028. PMID 16603238.
- Bonaldo MF, Lennon G, Soares MB (September 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it. |