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*{{cite journal |vauthors=Feng W, Tu J, Yang T, etal |title=Homer regulates gain of ryanodine receptor type 1 channel complex. |journal=J. Biol. Chem. |volume=277 |issue= 47 |pages= 44722–30 |year= 2003 |pmid= 12223488 |doi= 10.1074/jbc.M207675200 }} | *{{cite journal |vauthors=Feng W, Tu J, Yang T, etal |title=Homer regulates gain of ryanodine receptor type 1 channel complex. |journal=J. Biol. Chem. |volume=277 |issue= 47 |pages= 44722–30 |year= 2003 |pmid= 12223488 |doi= 10.1074/jbc.M207675200 }} | ||
*{{cite journal |vauthors=Kim JT, Park SH, Kim SK, etal |title=Potential role of Homer-2a on cutaneous vascular anomaly. |journal=J. Korean Med. Sci. |volume=17 |issue= 5 |pages= 636–40 |year= 2003 |pmid= 12378015 |doi= |pmc=3054924}} | *{{cite journal |vauthors=Kim JT, Park SH, Kim SK, etal |title=Potential role of Homer-2a on cutaneous vascular anomaly. |journal=J. Korean Med. Sci. |volume=17 |issue= 5 |pages= 636–40 |year= 2003 |pmid= 12378015 |doi= |pmc=3054924}} | ||
*{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }} | *{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }} | ||
*{{cite journal |vauthors=Shiraishi Y, Mizutani A, Mikoshiba K, Furuichi T |title=Coincidence in dendritic clustering and synaptic targeting of homer proteins and NMDA receptor complex proteins NR2B and PSD95 during development of cultured hippocampal neurons. |journal=Mol. Cell. Neurosci. |volume=22 |issue= 2 |pages= 188–201 |year= 2003 |pmid= 12676529 |doi=10.1016/S1044-7431(03)00037-X }} | *{{cite journal |vauthors=Shiraishi Y, Mizutani A, Mikoshiba K, Furuichi T |title=Coincidence in dendritic clustering and synaptic targeting of homer proteins and NMDA receptor complex proteins NR2B and PSD95 during development of cultured hippocampal neurons. |journal=Mol. Cell. Neurosci. |volume=22 |issue= 2 |pages= 188–201 |year= 2003 |pmid= 12676529 |doi=10.1016/S1044-7431(03)00037-X }} | ||
*{{cite journal |vauthors=Rong R, Ahn JY, Huang H, etal |title=PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis. |journal=Nat. Neurosci. |volume=6 |issue= 11 |pages= 1153–61 |year= 2003 |pmid= 14528310 |doi= 10.1038/nn1134 }} | *{{cite journal |vauthors=Rong R, Ahn JY, Huang H, etal |title=PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis. |journal=Nat. Neurosci. |volume=6 |issue= 11 |pages= 1153–61 |year= 2003 |pmid= 14528310 |doi= 10.1038/nn1134 }} | ||
*{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }} | *{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }} | ||
*{{cite journal |vauthors=Ishibashi T, Ogawa S, Hashiguchi Y, etal |title=A novel protein specifically interacting with Homer2 regulates ubiquitin-proteasome systems. |journal=J. Biochem. |volume=137 |issue= 5 |pages= 617–23 |year= 2005 |pmid= 15944415 |doi= 10.1093/jb/mvi074 }} | *{{cite journal |vauthors=Ishibashi T, Ogawa S, Hashiguchi Y, etal |title=A novel protein specifically interacting with Homer2 regulates ubiquitin-proteasome systems. |journal=J. Biochem. |volume=137 |issue= 5 |pages= 617–23 |year= 2005 |pmid= 15944415 |doi= 10.1093/jb/mvi074 }} | ||
*{{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }} | *{{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R }} | ||
*{{cite journal |vauthors=Dahl JP, Kampman KM, Oslin DW, etal |title=Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American population. |journal=Psychiatr. Genet. |volume=15 |issue= 4 |pages= 277–83 |year= 2006 |pmid= 16314758 |doi=10.1097/00041444-200512000-00010 }} | *{{cite journal |vauthors=Dahl JP, Kampman KM, Oslin DW, etal |title=Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American population. |journal=Psychiatr. Genet. |volume=15 |issue= 4 |pages= 277–83 |year= 2006 |pmid= 16314758 |doi=10.1097/00041444-200512000-00010 }} | ||
}} | }} | ||
Latest revision as of 12:44, 9 January 2019
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Homer protein homolog 2 is a protein that in humans is encoded by the HOMER2 gene.[1][2][3]
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein may be involved in cell growth. Four transcript variants encoding distinct isoforms have been identified for this gene.[3]
Interactions
HOMER2 has been shown to interact with RYR1.[4]
See also
References
- ↑ Tu JC, Xiao B, Yuan JP, Lanahan AA, Leoffert K, Li M, Linden DJ, Worley PF (Dec 1998). "Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors". Neuron. 21 (4): 717–26. doi:10.1016/S0896-6273(00)80589-9. PMID 9808459.
- ↑ Xiao B, Tu JC, Petralia RS, Yuan JP, Doan A, Breder CD, Ruggiero A, Lanahan AA, Wenthold RJ, Worley PF (Dec 1998). "Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins". Neuron. 21 (4): 707–16. doi:10.1016/S0896-6273(00)80588-7. PMID 9808458.
- ↑ 3.0 3.1 "Entrez Gene: HOMER2 homer homolog 2 (Drosophila)".
- ↑ Feng, Wei; Tu Jiancheng; Yang Tianzhong; Vernon Patty Shih; Allen Paul D; Worley Paul F; Pessah Isaac N (Nov 2002). "Homer regulates gain of ryanodine receptor type 1 channel complex". J. Biol. Chem. United States. 277 (47): 44722–30. doi:10.1074/jbc.M207675200. ISSN 0021-9258. PMID 12223488.
Further reading
- Soloviev MM, Ciruela F, Chan WY, McIlhinney RA (2000). "Molecular characterisation of two structurally distinct groups of human homers, generated by extensive alternative splicing". J. Mol. Biol. 295 (5): 1185–200. doi:10.1006/jmbi.1999.3436. PMID 10653696.
- Feng W, Tu J, Yang T, et al. (2003). "Homer regulates gain of ryanodine receptor type 1 channel complex". J. Biol. Chem. 277 (47): 44722–30. doi:10.1074/jbc.M207675200. PMID 12223488.
- Kim JT, Park SH, Kim SK, et al. (2003). "Potential role of Homer-2a on cutaneous vascular anomaly". J. Korean Med. Sci. 17 (5): 636–40. PMC 3054924. PMID 12378015.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Shiraishi Y, Mizutani A, Mikoshiba K, Furuichi T (2003). "Coincidence in dendritic clustering and synaptic targeting of homer proteins and NMDA receptor complex proteins NR2B and PSD95 during development of cultured hippocampal neurons". Mol. Cell. Neurosci. 22 (2): 188–201. doi:10.1016/S1044-7431(03)00037-X. PMID 12676529.
- Rong R, Ahn JY, Huang H, et al. (2003). "PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis". Nat. Neurosci. 6 (11): 1153–61. doi:10.1038/nn1134. PMID 14528310.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ishibashi T, Ogawa S, Hashiguchi Y, et al. (2005). "A novel protein specifically interacting with Homer2 regulates ubiquitin-proteasome systems". J. Biochem. 137 (5): 617–23. doi:10.1093/jb/mvi074. PMID 15944415.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.
- Dahl JP, Kampman KM, Oslin DW, et al. (2006). "Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American population". Psychiatr. Genet. 15 (4): 277–83. doi:10.1097/00041444-200512000-00010. PMID 16314758.
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