SMPD3: Difference between revisions
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'''Sphingomyelin phosphodiesterase 3''' is an [[enzyme]] that in humans is encoded by the ''SMPD3'' [[gene]].<ref name="pmid10823942">{{cite journal | vauthors = Hofmann K, Tomiuk S, Wolff G, Stoffel W | title = Cloning and characterization of the mammalian brain-specific, Mg2+-dependent neutral sphingomyelinase | journal = Proc Natl Acad Sci U S A | volume = 97 | issue = 11 | pages = 5895–900 |date=Jun 2000 | pmid = 10823942 | pmc = 18530 | doi =10.1073/pnas.97.11.5895 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55512| accessdate = }}</ref> | '''Sphingomyelin phosphodiesterase 3''' is an [[enzyme]] that in humans is encoded by the ''SMPD3'' [[gene]].<ref name="pmid10823942">{{cite journal | vauthors = Hofmann K, Tomiuk S, Wolff G, Stoffel W | title = Cloning and characterization of the mammalian brain-specific, Mg2+-dependent neutral sphingomyelinase | journal = Proc Natl Acad Sci U S A | volume = 97 | issue = 11 | pages = 5895–900 |date=Jun 2000 | pmid = 10823942 | pmc = 18530 | doi =10.1073/pnas.97.11.5895 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55512| accessdate = }}</ref> | ||
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*{{cite journal | vauthors=Jana A, Pahan K |title=Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase |journal=J. Neurosci. |volume=24 |issue= 43 |pages= 9531–40 |year= 2005 |pmid= 15509740 |doi= 10.1523/JNEUROSCI.3085-04.2004 | pmc=1955476 }} | *{{cite journal | vauthors=Jana A, Pahan K |title=Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase |journal=J. Neurosci. |volume=24 |issue= 43 |pages= 9531–40 |year= 2005 |pmid= 15509740 |doi= 10.1523/JNEUROSCI.3085-04.2004 | pmc=1955476 }} | ||
*{{cite journal |vauthors=Krut O, Wiegmann K, Kashkar H, etal |title=Novel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a C-tail-anchored protein |journal=J. Biol. Chem. |volume=281 |issue= 19 |pages= 13784–93 |year= 2006 |pmid= 16517606 |doi= 10.1074/jbc.M511306200 }} | *{{cite journal |vauthors=Krut O, Wiegmann K, Kashkar H, etal |title=Novel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a C-tail-anchored protein |journal=J. Biol. Chem. |volume=281 |issue= 19 |pages= 13784–93 |year= 2006 |pmid= 16517606 |doi= 10.1074/jbc.M511306200 }} | ||
*{{cite journal | vauthors=Levy M, Castillo SS, Goldkorn T |title=nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis |journal=Biochem. Biophys. Res. Commun. |volume=344 |issue= 3 |pages= 900–5 |year= 2006 |pmid= 16631623 |doi= 10.1016/j.bbrc.2006.04.013 }} | *{{cite journal | vauthors=Levy M, Castillo SS, Goldkorn T |title=nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis |journal=Biochem. Biophys. Res. Commun. |volume=344 |issue= 3 |pages= 900–5 |year= 2006 |pmid= 16631623 |doi= 10.1016/j.bbrc.2006.04.013 |pmc=4370275 }} | ||
*{{cite journal | vauthors=Clarke CJ, Truong TG, Hannun YA |title=Role for neutral sphingomyelinase-2 in tumor necrosis factor alpha-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells: p38 MAPK is an upstream regulator of nSMase2 |journal=J. Biol. Chem. |volume=282 |issue= 2 |pages= 1384–96 |year= 2007 |pmid= 17085432 |doi= 10.1074/jbc.M609216200 }} | *{{cite journal | vauthors=Clarke CJ, Truong TG, Hannun YA |title=Role for neutral sphingomyelinase-2 in tumor necrosis factor alpha-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells: p38 MAPK is an upstream regulator of nSMase2 |journal=J. Biol. Chem. |volume=282 |issue= 2 |pages= 1384–96 |year= 2007 |pmid= 17085432 |doi= 10.1074/jbc.M609216200 }} | ||
*{{cite journal | vauthors=Tani M, Hannun YA |title=Analysis of membrane topology of neutral sphingomyelinase 2 |journal=FEBS Lett. |volume=581 |issue= 7 |pages= 1323–8 |year= 2007 |pmid= 17349629 |doi= 10.1016/j.febslet.2007.02.046 | pmc=1868537 }} | *{{cite journal | vauthors=Tani M, Hannun YA |title=Analysis of membrane topology of neutral sphingomyelinase 2 |journal=FEBS Lett. |volume=581 |issue= 7 |pages= 1323–8 |year= 2007 |pmid= 17349629 |doi= 10.1016/j.febslet.2007.02.046 | pmc=1868537 }} | ||
Latest revision as of 09:20, 10 January 2019
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Sphingomyelin phosphodiesterase 3 is an enzyme that in humans is encoded by the SMPD3 gene.[1][2]
References
- ↑ Hofmann K, Tomiuk S, Wolff G, Stoffel W (Jun 2000). "Cloning and characterization of the mammalian brain-specific, Mg2+-dependent neutral sphingomyelinase". Proc Natl Acad Sci U S A. 97 (11): 5895–900. doi:10.1073/pnas.97.11.5895. PMC 18530. PMID 10823942.
- ↑ "Entrez Gene: SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)".
Further reading
- Chagnon P, Michaud J, Mitchell G, et al. (2003). "A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis". Am. J. Hum. Genet. 71 (6): 1443–9. doi:10.1086/344580. PMC 378590. PMID 12417987.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Marchesini N, Luberto C, Hannun YA (2003). "Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism". J. Biol. Chem. 278 (16): 13775–83. doi:10.1074/jbc.M212262200. PMID 12566438.
- Miura Y, Gotoh E, Nara F, et al. (2004). "Hydrolysis of sphingosylphosphocholine by neutral sphingomyelinases". FEBS Lett. 557 (1–3): 288–92. doi:10.1016/S0014-5793(03)01523-0. PMID 14741383.
- Marchesini N, Osta W, Bielawski J, et al. (2004). "Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells". J. Biol. Chem. 279 (24): 25101–11. doi:10.1074/jbc.M313662200. PMID 15051724.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Jana A, Pahan K (2005). "Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase". J. Neurosci. 24 (43): 9531–40. doi:10.1523/JNEUROSCI.3085-04.2004. PMC 1955476. PMID 15509740.
- Krut O, Wiegmann K, Kashkar H, et al. (2006). "Novel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a C-tail-anchored protein". J. Biol. Chem. 281 (19): 13784–93. doi:10.1074/jbc.M511306200. PMID 16517606.
- Levy M, Castillo SS, Goldkorn T (2006). "nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis". Biochem. Biophys. Res. Commun. 344 (3): 900–5. doi:10.1016/j.bbrc.2006.04.013. PMC 4370275. PMID 16631623.
- Clarke CJ, Truong TG, Hannun YA (2007). "Role for neutral sphingomyelinase-2 in tumor necrosis factor alpha-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells: p38 MAPK is an upstream regulator of nSMase2". J. Biol. Chem. 282 (2): 1384–96. doi:10.1074/jbc.M609216200. PMID 17085432.
- Tani M, Hannun YA (2007). "Analysis of membrane topology of neutral sphingomyelinase 2". FEBS Lett. 581 (7): 1323–8. doi:10.1016/j.febslet.2007.02.046. PMC 1868537. PMID 17349629.
- Filosto S, Fry W, Knowlton A, Goldkorn T (2010). "Neutral sphingomyelinase 2 (nSMase2) is a phosphoprotein regulated by calcineurin (PP2B)". JBC. 285 (14): 10213–22. doi:10.1074/jbc.M109.069963. PMC 2856226. PMID 20106976.
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