COG1: Difference between revisions

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{{Infobox_gene}}
{{Infobox_gene}}
'''Conserved oligomeric Golgi complex subunit 1''' is a [[protein]] that in humans is encoded by the ''COG1'' [[gene]].<ref name="pmid9927668">{{cite journal | vauthors = Chatterton JE, Hirsch D, Schwartz JJ, Bickel PE, Rosenberg RD, Lodish HF, Krieger M | title = Expression cloning of LDLB, a gene essential for normal Golgi function and assembly of the ldlCp complex | journal = Proc Natl Acad Sci U S A | volume = 96 | issue = 3 | pages = 915–20 |date=Mar 1999 | pmid = 9927668 | pmc = 15325 | doi =10.1073/pnas.96.3.915  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: COG1 component of oligomeric golgi complex 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9382| accessdate = }}</ref>
'''Conserved oligomeric Golgi complex subunit 1''' is a [[protein]] that in humans is encoded by the ''COG1'' [[gene]].<ref name="pmid9927668">{{cite journal | vauthors = Chatterton JE, Hirsch D, Schwartz JJ, Bickel PE, Rosenberg RD, Lodish HF, Krieger M | title = Expression cloning of LDLB, a gene essential for normal Golgi function and assembly of the ldlCp complex | journal = Proc Natl Acad Sci U S A | volume = 96 | issue = 3 | pages = 915–20 |date=Mar 1999 | pmid = 9927668 | pmc = 15325 | doi =10.1073/pnas.96.3.915  | bibcode = 1999PNAS...96..915C }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: COG1 component of oligomeric golgi complex 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9382| accessdate = }}</ref>


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| summary_text = The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.<ref name="entrez"/>
| summary_text = The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans-Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.<ref name="entrez"/>
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*{{cite journal  | vauthors=Loh E, Hong W |title=Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp. |journal=J. Biol. Chem. |volume=277 |issue= 24 |pages= 21955–61 |year= 2002 |pmid= 11929878 |doi= 10.1074/jbc.M202326200 }}
*{{cite journal  | vauthors=Loh E, Hong W |title=Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp. |journal=J. Biol. Chem. |volume=277 |issue= 24 |pages= 21955–61 |year= 2002 |pmid= 11929878 |doi= 10.1074/jbc.M202326200 }}
*{{cite journal  | vauthors=Ungar D, Oka T, Brittle EE |title=Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function. |journal=J. Cell Biol. |volume=157 |issue= 3 |pages= 405–15 |year= 2002 |pmid= 11980916 |doi= 10.1083/jcb.200202016  | pmc=2173297 |display-authors=etal}}
*{{cite journal  | vauthors=Ungar D, Oka T, Brittle EE |title=Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function. |journal=J. Cell Biol. |volume=157 |issue= 3 |pages= 405–15 |year= 2002 |pmid= 11980916 |doi= 10.1083/jcb.200202016  | pmc=2173297 |display-authors=etal}}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal|bibcode=2002PNAS...9916899M }}
*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
*{{cite journal  | vauthors=Loh E, Hong W |title=The binary interacting network of the conserved oligomeric Golgi tethering complex. |journal=J. Biol. Chem. |volume=279 |issue= 23 |pages= 24640–8 |year= 2004 |pmid= 15047703 |doi= 10.1074/jbc.M400662200 }}
*{{cite journal  | vauthors=Loh E, Hong W |title=The binary interacting network of the conserved oligomeric Golgi tethering complex. |journal=J. Biol. Chem. |volume=279 |issue= 23 |pages= 24640–8 |year= 2004 |pmid= 15047703 |doi= 10.1074/jbc.M400662200 }}

Latest revision as of 13:05, 17 December 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
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Wikidata
View/Edit Human

Conserved oligomeric Golgi complex subunit 1 is a protein that in humans is encoded by the COG1 gene.[1][2]

The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans-Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.[2]

Interactions

COG1 has been shown to interact with COG4[3] and COG3.[4]

References

  1. ↑ Chatterton JE, Hirsch D, Schwartz JJ, Bickel PE, Rosenberg RD, Lodish HF, Krieger M (Mar 1999). "Expression cloning of LDLB, a gene essential for normal Golgi function and assembly of the ldlCp complex". Proc Natl Acad Sci U S A. 96 (3): 915–20. Bibcode:1999PNAS...96..915C. doi:10.1073/pnas.96.3.915. PMC 15325. PMID 9927668.
  2. ↑ 2.0 2.1 "Entrez Gene: COG1 component of oligomeric golgi complex 1".
  3. ↑ Loh, Eva; Hong Wanjin (Jun 2004). "The binary interacting network of the conserved oligomeric Golgi tethering complex". J. Biol. Chem. United States. 279 (23): 24640–8. doi:10.1074/jbc.M400662200. ISSN 0021-9258. PMID 15047703.
  4. ↑ Loh, Eva; Hong Wanjin (Jun 2002). "Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp". J. Biol. Chem. United States. 277 (24): 21955–61. doi:10.1074/jbc.M202326200. ISSN 0021-9258. PMID 11929878.

Further reading

External links



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