Endogenous retrovirus group V member 2, envelope: Difference between revisions

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{{cite web
{{cite web
| title = Entrez Gene: Endogenous retrovirus group V member 2, envelope
| title = Entrez Gene: Endogenous retrovirus group V member 2, envelope
| url = http://www.ncbi.nlm.nih.gov/gene/100271846
| url = https://www.ncbi.nlm.nih.gov/gene/100271846
| accessdate = 2017-09-13
| accessdate = 2017-09-13
}}</ref>
}}</ref>

Latest revision as of 21:56, 19 December 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Endogenous retrovirus group V member 2, envelope is a protein that in humans is encoded by the ERVV-2 gene. [1]

Function

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on human chromosome 19 that has inactivating mutations in the gag and pol genes. This envelope glycoprotein gene appears to have been selectively preserved. The gene's protein product is expressed in the placenta and acts as a syncytin in Old World monkeys, but has lost the fusogenic activity in humans and other primate lineages.

References

  1. "Entrez Gene: Endogenous retrovirus group V member 2, envelope". Retrieved 2017-09-13.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.