HEPACAM2: Difference between revisions
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←Created page with '{{Infobox_gene}} '''HEPACAM family member 2''' is a protein that in humans is encoded by the HEPACAM2 gene. <ref name="entrez"> {{cite web | title = Ent...' |
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{{cite web | {{cite web | ||
| title = Entrez Gene: HEPACAM family member 2 | | title = Entrez Gene: HEPACAM family member 2 | ||
| url = | | url = https://www.ncbi.nlm.nih.gov/gene/253012 | ||
| accessdate = 2017-09-13 | | accessdate = 2017-09-13 | ||
}}</ref> | }}</ref> | ||
Latest revision as of 21:48, 19 December 2017
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| External IDs | GeneCards: [1] | ||||||
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| Location (UCSC) | n/a | n/a | |||||
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HEPACAM family member 2 is a protein that in humans is encoded by the HEPACAM2 gene. [1]
Function
This gene encodes a protein related to the immunoglobulin superfamily that plays a role in mitosis. Knockdown of this gene results in prometaphase arrest, abnormal nuclear morphology and apoptosis. Poly(ADP-ribosylation) of the encoded protein promotes its translocation to centrosomes, which may stimulate centrosome maturation. A chromosomal deletion including this gene may be associated with myeloid leukemia and myelodysplastic syndrome in human patients.
References
- ↑ "Entrez Gene: HEPACAM family member 2". Retrieved 2017-09-13.
Further reading
 | This article on a gene on human chromosome 7 is a stub. You can help Wikipedia by expanding it. |
This article incorporates text from the United States National Library of Medicine, which is in the public domain.