Complement receptor of the immunoglobulin family: Difference between revisions

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'''Complement receptor of the immunoglobulin family''' is a [[protein]] expressed in [[Kupffer cell]]s.<ref>{{cite journal | vauthors = Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M | title = CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens. | journal = Cell | volume = 124 | issue = 5 | pages = 915–27 | year = 2006 | pmid = 16530040 | doi = 10.1016/j.cell.2005.12.039}}</ref>It is a critical receptor for the [[phagocytosis]] of [[Opsonin|opsonised]] particles in the [[blood]]. It recognizes [[iC3b]] (inactivated C3b) deposited on microbial surfaces.
'''Complement receptor of the immunoglobulin family''' is a [[protein]] expressed in [[Kupffer cell]]s.<ref>{{cite journal | vauthors = Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M | title = CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens | journal = Cell | volume = 124 | issue = 5 | pages = 915–27 | year = 2006 | pmid = 16530040 | doi = 10.1016/j.cell.2005.12.039}}</ref>It is a critical receptor for the [[phagocytosis]] of [[Opsonin|opsonised]] particles in the [[blood]]. It recognizes [[iC3b]] (inactivated C3b) deposited on microbial surfaces.


==See also==
==See also==

Latest revision as of 22:30, 5 September 2018

V-set and immunoglobulin domain containing 4
Identifiers
SymbolVSIG4
Entrez11326
HUGO17032
OMIM300353
RefSeqNM_007268
UniProtQ9Y279
Other data
LocusChr. X q12-q13.3

Complement receptor of the immunoglobulin family is a protein expressed in Kupffer cells.[1]It is a critical receptor for the phagocytosis of opsonised particles in the blood. It recognizes iC3b (inactivated C3b) deposited on microbial surfaces.

See also

References

  1. Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M (2006). "CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens". Cell. 124 (5): 915–27. doi:10.1016/j.cell.2005.12.039. PMID 16530040.