Glypican 4: Difference between revisions
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'''Glypican-4''' is a [[protein]] that in humans is encoded by the ''GPC4'' [[gene]].<ref name="pmid9787072">{{cite journal |vauthors=Veugelers M, Vermeesch J, Watanabe K, Yamaguchi Y, Marynen P, David G | title = GPC4, the gene for human K-glypican, flanks GPC3 on xq26: deletion of the GPC3-GPC4 gene cluster in one family with Simpson-Golabi-Behmel syndrome | journal = Genomics | volume = 53 | issue = 1 | pages = 1–11 |date=Dec 1998 | pmid = 9787072 | pmc = | doi = 10.1006/geno.1998.5465 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GPC4 glypican 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2239| accessdate = }}</ref> | '''Glypican-4''' is a [[protein]] that in humans is encoded by the ''GPC4'' [[gene]].<ref name="pmid9787072">{{cite journal |vauthors=Veugelers M, Vermeesch J, Watanabe K, Yamaguchi Y, Marynen P, David G | title = GPC4, the gene for human K-glypican, flanks GPC3 on xq26: deletion of the GPC3-GPC4 gene cluster in one family with Simpson-Golabi-Behmel syndrome | journal = Genomics | volume = 53 | issue = 1 | pages = 1–11 |date=Dec 1998 | pmid = 9787072 | pmc = | doi = 10.1006/geno.1998.5465 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GPC4 glypican 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2239| accessdate = }}</ref> | ||
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*{{cite journal |vauthors=Ross MT, Grafham DV, Coffey AJ, etal |title=The DNA sequence of the human X chromosome | *{{cite journal |vauthors=Ross MT, Grafham DV, Coffey AJ, etal |title=The DNA sequence of the human X chromosome |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 | pmc=2665286 }} | ||
*{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) | *{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }} | ||
*{{cite journal |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment | *{{cite journal |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 }} | ||
*{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences | *{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }} | ||
*{{cite journal |vauthors=Sheu TJ, Schwarz EM, O'Keefe RJ, etal |title=Use of a phage display technique to identify potential osteoblast binding sites within osteoclast lacunae | *{{cite journal |vauthors=Sheu TJ, Schwarz EM, O'Keefe RJ, etal |title=Use of a phage display technique to identify potential osteoblast binding sites within osteoclast lacunae |journal=J. Bone Miner. Res. |volume=17 |issue= 5 |pages= 915–22 |year= 2002 |pmid= 12009023 |doi=10.1359/jbmr.2002.17.5.915 }} | ||
*{{cite journal |vauthors=Karumanchi SA, Jha V, Ramchandran R, etal |title=Cell surface glypicans are low-affinity endostatin receptors | *{{cite journal |vauthors=Karumanchi SA, Jha V, Ramchandran R, etal |title=Cell surface glypicans are low-affinity endostatin receptors |journal=Mol. Cell |volume=7 |issue= 4 |pages= 811–22 |year= 2001 |pmid= 11336704 |doi=10.1016/S1097-2765(01)00225-8 }} | ||
*{{cite journal |vauthors=Hagihara K, Watanabe K, Chun J, Yamaguchi Y |title=Glypican-4 is an FGF2-binding heparan sulfate proteoglycan expressed in neural precursor cells | *{{cite journal |vauthors=Hagihara K, Watanabe K, Chun J, Yamaguchi Y |title=Glypican-4 is an FGF2-binding heparan sulfate proteoglycan expressed in neural precursor cells |journal=Dev. Dyn. |volume=219 |issue= 3 |pages= 353–67 |year= 2000 |pmid= 11066092 |doi= 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1059>3.0.CO;2-# |doi-broken-date=2018-09-06 }} | ||
*{{cite journal |vauthors=Veugelers M, Cat BD, Muyldermans SY, etal |title=Mutational analysis of the GPC3/GPC4 glypican gene cluster on Xq26 in patients with Simpson-Golabi-Behmel syndrome: identification of loss-of-function mutations in the GPC3 gene | *{{cite journal |vauthors=Veugelers M, Cat BD, Muyldermans SY, etal |title=Mutational analysis of the GPC3/GPC4 glypican gene cluster on Xq26 in patients with Simpson-Golabi-Behmel syndrome: identification of loss-of-function mutations in the GPC3 gene |journal=Hum. Mol. Genet. |volume=9 |issue= 9 |pages= 1321–8 |year= 2000 |pmid= 10814714 |doi=10.1093/hmg/9.9.1321 }} | ||
*{{cite journal |vauthors=Siebertz B, Stöcker G, Drzeniek Z, etal |title=Expression of glypican-4 in haematopoietic-progenitor and bone-marrow-stromal cells | *{{cite journal |vauthors=Siebertz B, Stöcker G, Drzeniek Z, etal |title=Expression of glypican-4 in haematopoietic-progenitor and bone-marrow-stromal cells | series=344 |journal=Biochem. J. |volume=Pt 3 |issue= |pages= 937–43 |year= 2000 |pmid= 10585884 |doi= | pmc=1220719 }} | ||
*{{cite journal |vauthors=Huber R, Mazzarella R, Chen CN, etal |title=Glypican 3 and glypican 4 are juxtaposed in Xq26.1 | *{{cite journal |vauthors=Huber R, Mazzarella R, Chen CN, etal |title=Glypican 3 and glypican 4 are juxtaposed in Xq26.1 |journal=Gene |volume=225 |issue= 1–2 |pages= 9–16 |year= 1999 |pmid= 9931407 |doi=10.1016/S0378-1119(98)00549-6 |url=https://zenodo.org/record/1260055 }} | ||
*{{cite journal |vauthors=Watanabe K, Yamada H, Yamaguchi Y |title=K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney | *{{cite journal |vauthors=Watanabe K, Yamada H, Yamaguchi Y |title=K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney |journal=J. Cell Biol. |volume=130 |issue= 5 |pages= 1207–18 |year= 1995 |pmid= 7657705 |doi=10.1083/jcb.130.5.1207 | pmc=2120559 }} | ||
}} | }} | ||
{{refend}} | {{refend}} | ||
Latest revision as of 05:36, 12 January 2019
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Glypican-4 is a protein that in humans is encoded by the GPC4 gene.[1][2]
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.[2]
See also
References
- ↑ Veugelers M, Vermeesch J, Watanabe K, Yamaguchi Y, Marynen P, David G (Dec 1998). "GPC4, the gene for human K-glypican, flanks GPC3 on xq26: deletion of the GPC3-GPC4 gene cluster in one family with Simpson-Golabi-Behmel syndrome". Genomics. 53 (1): 1–11. doi:10.1006/geno.1998.5465. PMID 9787072.
- ↑ 2.0 2.1 "Entrez Gene: GPC4 glypican 4".
Further reading
- Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Sheu TJ, Schwarz EM, O'Keefe RJ, et al. (2002). "Use of a phage display technique to identify potential osteoblast binding sites within osteoclast lacunae". J. Bone Miner. Res. 17 (5): 915–22. doi:10.1359/jbmr.2002.17.5.915. PMID 12009023.
- Karumanchi SA, Jha V, Ramchandran R, et al. (2001). "Cell surface glypicans are low-affinity endostatin receptors". Mol. Cell. 7 (4): 811–22. doi:10.1016/S1097-2765(01)00225-8. PMID 11336704.
- Hagihara K, Watanabe K, Chun J, Yamaguchi Y (2000). "Glypican-4 is an FGF2-binding heparan sulfate proteoglycan expressed in neural precursor cells". Dev. Dyn. 219 (3): 353–67. doi:10.1002/1097-0177(2000)9999:9999<::AID-DVDY1059>3.0.CO;2-# (inactive 2018-09-06). PMID 11066092.
- Veugelers M, Cat BD, Muyldermans SY, et al. (2000). "Mutational analysis of the GPC3/GPC4 glypican gene cluster on Xq26 in patients with Simpson-Golabi-Behmel syndrome: identification of loss-of-function mutations in the GPC3 gene". Hum. Mol. Genet. 9 (9): 1321–8. doi:10.1093/hmg/9.9.1321. PMID 10814714.
- Siebertz B, Stöcker G, Drzeniek Z, et al. (2000). "Expression of glypican-4 in haematopoietic-progenitor and bone-marrow-stromal cells". Biochem. J. 344. Pt 3: 937–43. PMC 1220719. PMID 10585884.
- Huber R, Mazzarella R, Chen CN, et al. (1999). "Glypican 3 and glypican 4 are juxtaposed in Xq26.1". Gene. 225 (1–2): 9–16. doi:10.1016/S0378-1119(98)00549-6. PMID 9931407.
- Watanabe K, Yamada H, Yamaguchi Y (1995). "K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney". J. Cell Biol. 130 (5): 1207–18. doi:10.1083/jcb.130.5.1207. PMC 2120559. PMID 7657705.
External links
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