Grb2 associated binding protein 3: Difference between revisions

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Latest revision as of 20:57, 13 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

GRB2 associated binding protein 3 is a protein that in humans is encoded by the GAB3 gene. [1]

Function

This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants.

References

  1. "Entrez Gene: GRB2 associated binding protein 3". Retrieved 2016-07-26.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.