Inguinal hernia pathophysiology: Difference between revisions
Jump to navigation
Jump to search
Farima Kahe (talk | contribs) No edit summary |
|||
| (26 intermediate revisions by one other user not shown) | |||
| Line 1: | Line 1: | ||
__NOTOC__ | |||
{{Inguinal hernia}} | |||
{{CMG}}; {{AE}} {{F.K}} | |||
{{ | |||
==Overview== | ==Overview== | ||
Directed inguinal hernia is caused by protrusion through Hesselbach triangle, passes medial to inferior epigastric vessels. Indirected inguinal hernia is caused by passes through internal [[inguinal ring]], traverses [[inguinal canal]] to external ring, and may extend into [[scrotum]] in males and [[labia majora]] in females. | |||
[ | |||
[ | |||
==Pathophysiology== | ==Pathophysiology== | ||
===Pathogenesis=== | ===Pathogenesis=== | ||
*It is understood that indirect inguinal hernia is caused by:<ref name="pmid6353636">{{cite journal |vauthors=Berliner SD |title=Adult inguinal hernia: pathophysiology and repair |journal=Surg Annu |volume=15 |issue= |pages=307–29 |year=1983 |pmid=6353636 |doi= |url=}}</ref><ref name="pmid18244999">{{cite journal |vauthors=Jenkins JT, O'Dwyer PJ |title=Inguinal hernias |journal=BMJ |volume=336 |issue=7638 |pages=269–72 |year=2008 |pmid=18244999 |pmc=2223000 |doi=10.1136/bmj.39450.428275.AD |url=}}</ref> | |||
**Passes through internal inguinal ring, traverses [[inguinal canal]] to external ring | |||
*It is understood that | **May extend into scrotum in males and [[labia majora|labia major]] in females | ||
*[ | **Passes lateral to inferior epigastric vessels and has an [[oblique]] inferior course | ||
* | **Considered a congenital defect and associated with a patent [[processus vaginalis]] | ||
*[ | *It is understood that directed inguinal hernia is caused by: | ||
* | **Protrusion through Hesselbach triangle | ||
**Generally does not extend into [[scrotum]] | |||
**Passes medial to inferior epigastric vessels | |||
**Considered an [[acquired]] defect | |||
== | {{Family tree/start}} | ||
{{Family tree |boxstyle=text-align: left; | | | | A01 | | | | A02 | |A01='''Predisposing factors'''<br>•Being male<br>•Having muscle weakness from birth along with a hernia sac<br>•Having muscle weakness from aging<br>•Having one or more inguinal hernia | A02='''Precipitating factors'''<br>•Being overweight or having a recent,large weight loss<br>•Having weak abdominal muscles from poor diet, lack of exercise or both<br>•Straining during urination or bowel movements<br>•Chronic cough,such as from smoking}} | |||
{{Family tree | | | | |`|-|-|v|-|-|'| | | }} | |||
{{Family tree | | | | | | | B01| | | | |B01=Incresed pressure in the compartment of the abdomen in develops}} | |||
{{Family tree | | | | | | | |!| | | | | }} | |||
{{Family tree | | | | | | | C01| | | | |C01=Intra-abdominal wall of inguinal canal into the scrotum becomes weakend}} | |||
{{Family tree | | | | | | | |!| | | | | }} | |||
{{Family tree | | | | | | | D01| | | | |D01=Causing the inguinal ring not to close}} | |||
{{Family tree | | | | | | | |!| | | | | }} | |||
{{Family tree | | | | | | | E01| | | | |E01=Evolves into a hole or defect}} | |||
{{Family tree | | | | | | | |!| | | | | }} | |||
{{Family tree | | | | | | | F01| | | | |F01=Fat or part of the small intestine slides through the inguinal canal}} | |||
{{Family tree | | |,|-|-|-|-|+|-|-|-|-|.| }} | |||
{{Family tree | | G01| | | G02 | | | | G03| |G01=Swollen or enlarged scrotum| G02=Feeling of weakness or pressure in the groin| G03=Pain or discomfort}} | |||
{{Family tree/end}} | |||
== | ==Genetics== | ||
* | *Genes involved in the [[pathogenesis]] of inguinal hernia include microdeletion disorders such as 22q11.2 microdeletion.<ref name="pmid19573673">{{cite journal |vauthors=Barnett C, Langer JC, Hinek A, Bradley TJ, Chitayat D |title=Looking past the lump: genetic aspects of inguinal hernia in children |journal=J. Pediatr. Surg. |volume=44 |issue=7 |pages=1423–31 |year=2009 |pmid=19573673 |doi=10.1016/j.jpedsurg.2008.12.022 |url=}}</ref> | ||
==Microscopic Pathology== | ==Microscopic Pathology== | ||
*On microscopic histopathological analysis, [ | *On microscopic histopathological analysis, inflammatory infiltration, [[vascular]] damage and regressive nerve lesions, fibrohyaline [[degeneration]] and fatty [[dystrophy]] of the muscle fibers are characteristic findings of inguinal hernia. <ref name="pmid23288217">{{cite journal |vauthors=Amato G, Agrusa A, Romano G, Salamone G, Cocorullo G, Mularo SA, Marasa S, Gulotta G |title=Histological findings in direct inguinal hernia : investigating the histological changes of the herniated groin looking forward to ascertain the pathogenesis of hernia disease |journal=Hernia |volume=17 |issue=6 |pages=757–63 |year=2013 |pmid=23288217 |doi=10.1007/s10029-012-1032-0 |url=}}</ref> | ||
==References== | ==References== | ||
| Line 66: | Line 50: | ||
{{WS}} | {{WS}} | ||
[[Category: (name of the system)]] | [[Category: (name of the system)]] | ||
Latest revision as of 15:15, 29 January 2018
|
Inguinal hernia Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Inguinal hernia pathophysiology On the Web |
|
American Roentgen Ray Society Images of Inguinal hernia pathophysiology |
|
Risk calculators and risk factors for Inguinal hernia pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
Overview
Directed inguinal hernia is caused by protrusion through Hesselbach triangle, passes medial to inferior epigastric vessels. Indirected inguinal hernia is caused by passes through internal inguinal ring, traverses inguinal canal to external ring, and may extend into scrotum in males and labia majora in females.
Pathophysiology
Pathogenesis
- It is understood that indirect inguinal hernia is caused by:[1][2]
- Passes through internal inguinal ring, traverses inguinal canal to external ring
- May extend into scrotum in males and labia major in females
- Passes lateral to inferior epigastric vessels and has an oblique inferior course
- Considered a congenital defect and associated with a patent processus vaginalis
- It is understood that directed inguinal hernia is caused by:
| Predisposing factors •Being male •Having muscle weakness from birth along with a hernia sac •Having muscle weakness from aging •Having one or more inguinal hernia | Precipitating factors •Being overweight or having a recent,large weight loss •Having weak abdominal muscles from poor diet, lack of exercise or both •Straining during urination or bowel movements •Chronic cough,such as from smoking | ||||||||||||||||||||||||||||||
| Incresed pressure in the compartment of the abdomen in develops | |||||||||||||||||||||||||||||||
| Intra-abdominal wall of inguinal canal into the scrotum becomes weakend | |||||||||||||||||||||||||||||||
| Causing the inguinal ring not to close | |||||||||||||||||||||||||||||||
| Evolves into a hole or defect | |||||||||||||||||||||||||||||||
| Fat or part of the small intestine slides through the inguinal canal | |||||||||||||||||||||||||||||||
| Swollen or enlarged scrotum | Feeling of weakness or pressure in the groin | Pain or discomfort | |||||||||||||||||||||||||||||
Genetics
- Genes involved in the pathogenesis of inguinal hernia include microdeletion disorders such as 22q11.2 microdeletion.[3]
Microscopic Pathology
- On microscopic histopathological analysis, inflammatory infiltration, vascular damage and regressive nerve lesions, fibrohyaline degeneration and fatty dystrophy of the muscle fibers are characteristic findings of inguinal hernia. [4]
References
- ↑ Berliner SD (1983). "Adult inguinal hernia: pathophysiology and repair". Surg Annu. 15: 307–29. PMID 6353636.
- ↑ Jenkins JT, O'Dwyer PJ (2008). "Inguinal hernias". BMJ. 336 (7638): 269–72. doi:10.1136/bmj.39450.428275.AD. PMC 2223000. PMID 18244999.
- ↑ Barnett C, Langer JC, Hinek A, Bradley TJ, Chitayat D (2009). "Looking past the lump: genetic aspects of inguinal hernia in children". J. Pediatr. Surg. 44 (7): 1423–31. doi:10.1016/j.jpedsurg.2008.12.022. PMID 19573673.
- ↑ Amato G, Agrusa A, Romano G, Salamone G, Cocorullo G, Mularo SA, Marasa S, Gulotta G (2013). "Histological findings in direct inguinal hernia : investigating the histological changes of the herniated groin looking forward to ascertain the pathogenesis of hernia disease". Hernia. 17 (6): 757–63. doi:10.1007/s10029-012-1032-0. PMID 23288217.