Ileus laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
There are no [[diagnostic]] laboratory findings associated with [[ileus]]. However, laboratory evaluations must be done to identify the severity and presence of other [[Complication (medicine)|complications]] of [[ileus]] such as [[electrolyte abnormalities]] and [[hypovolemia]]. Common laboratory test include [[complete blood count]], [[Liver function test|liver function test]], [[renal function test]], [[Electrolyte|serum electrolytes]], serum [[lipase]] and [[amylase]], [[arterial blood gas]], [Lactic acid|lactate level]], serum [[albumin]] and measurement of [[inflammatory]] markers. | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
Laboratory findings in [[patient|patients]] of [[ileus]] includes<ref name="pmid25503902">{{cite journal |vauthors=Wu Z, Boersema GS, Dereci A, Menon AG, Jeekel J, Lange JF |title=Clinical endpoint, early detection, and differential diagnosis of postoperative ileus: a systematic review of the literature |journal=Eur Surg Res |volume=54 |issue=3-4 |pages=127–38 |year=2015 |pmid=25503902 |doi=10.1159/000369529 |url=}}</ref><ref name="pmid21233608">{{cite journal |vauthors=Kronberg U, Kiran RP, Soliman MS, Hammel JP, Galway U, Coffey JC, Fazio VW |title=A characterization of factors determining postoperative ileus after laparoscopic colectomy enables the generation of a novel predictive score |journal=Ann. Surg. |volume=253 |issue=1 |pages=78–81 |year=2011 |pmid=21233608 |doi=10.1097/SLA.0b013e3181fcb83e |url=}}</ref> | |||
* | *[[Complete blood count|CBC]]: It may show [[anemia]], increased [[White blood cells|total leukocyte count]] suggestive of [[infection]] | ||
* | *[[Liver function tests]]: Deranged [[Liver function tests|LFT]] may cause [[ileus]] | ||
* | *[[Renal function tests|Renal function test]]: [[blood urea nitrogen]] and [[creatinin]] should be evaluated in order to exclude concurrent [[Renal function tests|renal function test]] in a [[patient]] with [[ileus]] | ||
* | *Serum [[Electrolyte|electrolytes]]: [[hypokalemia]], [[hypomagnesemia]], [[hypocalcemia]] and [[hyponatremia]] all contribute to [[muscle]] [[paralysis]] | ||
* | *Serum [[lipase]] and [[amylase]]: [[Acute pancreatitis|Acute]] or [[chronic pancreatitis]] may alter [[gastrointestinal tract]] function and should be checked to rule out [[pancreatitis]] as a cause of [[ileus]] | ||
* | *Serum [[albumin]] and [[prealbumin]]: To identify the presence of [[ascites]] | ||
*Measurements of [[inflammation|inflammatory]] markers such as [[Interleukin 1|interleukins 1]] and [[Interleukin 6|6]] ([[Interleukin 1|IL-1]], [[Interleukin 6|IL-6]]α) and [[tumor necrosis factor alpha]] ([[tumor necrosis factor alpha|TNF-α]]) | |||
*[[Arterial blood gas]] ([[Arterial blood gas|ABG]]) and [[Lactic acid|lactate level]]: To evaluate possible [[intestine|intestinal]] [[shock|hypoperfusion]] and [[necrosis]] | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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[[Category:Medicine]] | |||
[[Category:Gastroenterology]] | |||
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Latest revision as of 19:20, 11 October 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]
Overview
There are no diagnostic laboratory findings associated with ileus. However, laboratory evaluations must be done to identify the severity and presence of other complications of ileus such as electrolyte abnormalities and hypovolemia. Common laboratory test include complete blood count, liver function test, renal function test, serum electrolytes, serum lipase and amylase, arterial blood gas, [Lactic acid|lactate level]], serum albumin and measurement of inflammatory markers.
Laboratory Findings
Laboratory findings in patients of ileus includes[1][2]
- CBC: It may show anemia, increased total leukocyte count suggestive of infection
- Liver function tests: Deranged LFT may cause ileus
- Renal function test: blood urea nitrogen and creatinin should be evaluated in order to exclude concurrent renal function test in a patient with ileus
- Serum electrolytes: hypokalemia, hypomagnesemia, hypocalcemia and hyponatremia all contribute to muscle paralysis
- Serum lipase and amylase: Acute or chronic pancreatitis may alter gastrointestinal tract function and should be checked to rule out pancreatitis as a cause of ileus
- Serum albumin and prealbumin: To identify the presence of ascites
- Measurements of inflammatory markers such as interleukins 1 and 6 (IL-1, IL-6α) and tumor necrosis factor alpha (TNF-α)
- Arterial blood gas (ABG) and lactate level: To evaluate possible intestinal hypoperfusion and necrosis
References
- ↑ Wu Z, Boersema GS, Dereci A, Menon AG, Jeekel J, Lange JF (2015). "Clinical endpoint, early detection, and differential diagnosis of postoperative ileus: a systematic review of the literature". Eur Surg Res. 54 (3–4): 127–38. doi:10.1159/000369529. PMID 25503902.
- ↑ Kronberg U, Kiran RP, Soliman MS, Hammel JP, Galway U, Coffey JC, Fazio VW (2011). "A characterization of factors determining postoperative ileus after laparoscopic colectomy enables the generation of a novel predictive score". Ann. Surg. 253 (1): 78–81. doi:10.1097/SLA.0b013e3181fcb83e. PMID 21233608.
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