Cystic fibrosis MRI: Difference between revisions
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==Overview== | ==Overview== | ||
[[Magnetic resonance imaging|MRI]] may be helpful in determining the cause of linear [[lung]] markings in cystic fibrosis. It is also helpful in [[Differentiating (disease name) from other diseases page|differentiating]] [[Mucoid plaque|mucous plugging]] and [[Peribronchial cuffing|peribronchial thickening]] from normal [[Pulmonary blood vessel|pulmonary blood vessels]]. Because of [[Magnetic resonance imaging|MRI]] absence of [[Ionizing radiation|ionising radiation]] and possibility for obtaining functional information, it is helpful for assessing [[Respiratory disease|lung disease]] in children who require repetitive follow up [[imaging]] for a long time. [[Magnetic resonance imaging|MRI studies]] of the [[pancreas]] have demonstrated different patterns of fatty infiltration, [[Duct (anatomy)|ductal]] changes, [[Pancreatic cyst|pancreatic cysts]], [[Calcification|calcifications]] and hypoechoic areas representing [[fibrosis]]. | |||
==MRI== | ==MRI== | ||
*Lung [[Magnetic resonance imaging|MRI]] may be helpful in the diagnosis of cystic fibrosis. It demonstrates structural and [[perfusion]] abnormalities in children and young people with cystic fibrosis. | *Lung [[Magnetic resonance imaging|MRI]] may be helpful in the diagnosis of cystic fibrosis. It demonstrates structural and [[perfusion]] abnormalities in children and young people with cystic fibrosis. | ||
*[[Magnetic resonance imaging|MRI]] may be helpful in determining the cause of linear lung markings in cystic fibrosis. It is also helpful in [[Differentiating (disease name) from other diseases page|differentiating]] [[Mucoid plaque|mucous plugging]] and peribronchial thickening from normal [[Pulmonary blood vessel|pulmonary blood vessels]]. | *[[Magnetic resonance imaging|MRI]] may be helpful in determining the cause of linear lung markings in cystic fibrosis. It is also helpful in [[Differentiating (disease name) from other diseases page|differentiating]] [[Mucoid plaque|mucous plugging]] and [[Peribronchial cuffing|peribronchial thickening]] from normal [[Pulmonary blood vessel|pulmonary blood vessels]]. | ||
*Because of [[Magnetic resonance imaging|MRI]] absence of [[Ionizing radiation|ionising radiation]] and possibility for obtaining functional information, it is helpful for assessing lung disease in children who require repetitive follow up imaging for a long time.<ref name="pmid29143200">{{cite journal |vauthors=Amaxopoulou C, Gnannt R, Higashigaito K, Jung A, Kellenberger CJ |title=Structural and perfusion magnetic resonance imaging of the lung in cystic fibrosis |journal=Pediatr Radiol |volume=48 |issue=2 |pages=165–175 |date=February 2018 |pmid=29143200 |doi=10.1007/s00247-017-4021-8 |url=}}</ref><ref name="pmid1475543">{{cite journal |vauthors=Grum CM, Lynch JP |title=Chest radiographic findings in cystic fibrosis |journal=Semin Respir Infect |volume=7 |issue=3 |pages=193–209 |date=September 1992 |pmid=1475543 |doi= |url=}}</ref> | *Because of [[Magnetic resonance imaging|MRI]] absence of [[Ionizing radiation|ionising radiation]] and possibility for obtaining functional information, it is helpful for assessing lung disease in children who require repetitive follow up imaging for a long time.<ref name="pmid29143200">{{cite journal |vauthors=Amaxopoulou C, Gnannt R, Higashigaito K, Jung A, Kellenberger CJ |title=Structural and perfusion magnetic resonance imaging of the lung in cystic fibrosis |journal=Pediatr Radiol |volume=48 |issue=2 |pages=165–175 |date=February 2018 |pmid=29143200 |doi=10.1007/s00247-017-4021-8 |url=}}</ref><ref name="pmid1475543">{{cite journal |vauthors=Grum CM, Lynch JP |title=Chest radiographic findings in cystic fibrosis |journal=Semin Respir Infect |volume=7 |issue=3 |pages=193–209 |date=September 1992 |pmid=1475543 |doi= |url=}}</ref> | ||
* In cystic fibrosis the [[Sensitivity (tests)|sensitivity]] of [[Magnetic resonance imaging|MRI]] in presenting [[Pancreas|pancreatic]] abnormality is 94%.<ref name="pmid2006275">{{cite journal |vauthors=Tham RT, Heyerman HG, Falke TH, Zwinderman AH, Bloem JL, Bakker W, Lamers CB |title=Cystic fibrosis: MR imaging of the pancreas |journal=Radiology |volume=179 |issue=1 |pages=183–6 |date=April 1991 |pmid=2006275 |doi=10.1148/radiology.179.1.2006275 |url=}}</ref> | * In cystic fibrosis the [[Sensitivity (tests)|sensitivity]] of [[Magnetic resonance imaging|MRI]] in presenting [[Pancreas|pancreatic]] abnormality is 94%.<ref name="pmid2006275">{{cite journal |vauthors=Tham RT, Heyerman HG, Falke TH, Zwinderman AH, Bloem JL, Bakker W, Lamers CB |title=Cystic fibrosis: MR imaging of the pancreas |journal=Radiology |volume=179 |issue=1 |pages=183–6 |date=April 1991 |pmid=2006275 |doi=10.1148/radiology.179.1.2006275 |url=}}</ref> | ||
* MRI studies of the pancreas have demonstrated: <ref name="pmid25803445">{{cite journal |vauthors=Engjom T, Erchinger F, Lærum BN, Tjora E, Gilja OH, Dimcevski G |title=Ultrasound echo-intensity predicts severe pancreatic affection in cystic fibrosis patients |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121121 |date=2015 |pmid=25803445 |pmc=4372286 |doi=10.1371/journal.pone.0121121 |url=}}</ref> | |||
** Different patterns of fatty infiltration: | |||
*** Diffuse fatty replacement | |||
*** Partial fatty replacement | |||
*** Pancreatic atrophy | |||
** Ductal changes | |||
** Pancreatic cysts (ranging from small to severe pancreatic cystosis) | |||
** Calcifications | |||
** Hypoechoic areas representing fibrosis | |||
==References== | ==References== | ||
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[[Category:Medicine]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Gastroenterology]] | |||
[[Category:Pediatrics]] | |||
[[Category:Pulmonology]] | |||
Latest revision as of 20:55, 9 March 2018
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Cystic fibrosis MRI On the Web |
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American Roentgen Ray Society Images of Cystic fibrosis MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
Overview
MRI may be helpful in determining the cause of linear lung markings in cystic fibrosis. It is also helpful in differentiating mucous plugging and peribronchial thickening from normal pulmonary blood vessels. Because of MRI absence of ionising radiation and possibility for obtaining functional information, it is helpful for assessing lung disease in children who require repetitive follow up imaging for a long time. MRI studies of the pancreas have demonstrated different patterns of fatty infiltration, ductal changes, pancreatic cysts, calcifications and hypoechoic areas representing fibrosis.
MRI
- Lung MRI may be helpful in the diagnosis of cystic fibrosis. It demonstrates structural and perfusion abnormalities in children and young people with cystic fibrosis.
- MRI may be helpful in determining the cause of linear lung markings in cystic fibrosis. It is also helpful in differentiating mucous plugging and peribronchial thickening from normal pulmonary blood vessels.
- Because of MRI absence of ionising radiation and possibility for obtaining functional information, it is helpful for assessing lung disease in children who require repetitive follow up imaging for a long time.[1][2]
- In cystic fibrosis the sensitivity of MRI in presenting pancreatic abnormality is 94%.[3]
- MRI studies of the pancreas have demonstrated: [4]
- Different patterns of fatty infiltration:
- Diffuse fatty replacement
- Partial fatty replacement
- Pancreatic atrophy
- Ductal changes
- Pancreatic cysts (ranging from small to severe pancreatic cystosis)
- Calcifications
- Hypoechoic areas representing fibrosis
- Different patterns of fatty infiltration:
References
- ↑ Amaxopoulou C, Gnannt R, Higashigaito K, Jung A, Kellenberger CJ (February 2018). "Structural and perfusion magnetic resonance imaging of the lung in cystic fibrosis". Pediatr Radiol. 48 (2): 165–175. doi:10.1007/s00247-017-4021-8. PMID 29143200.
- ↑ Grum CM, Lynch JP (September 1992). "Chest radiographic findings in cystic fibrosis". Semin Respir Infect. 7 (3): 193–209. PMID 1475543.
- ↑ Tham RT, Heyerman HG, Falke TH, Zwinderman AH, Bloem JL, Bakker W, Lamers CB (April 1991). "Cystic fibrosis: MR imaging of the pancreas". Radiology. 179 (1): 183–6. doi:10.1148/radiology.179.1.2006275. PMID 2006275.
- ↑ Engjom T, Erchinger F, Lærum BN, Tjora E, Gilja OH, Dimcevski G (2015). "Ultrasound echo-intensity predicts severe pancreatic affection in cystic fibrosis patients". PLoS ONE. 10 (3): e0121121. doi:10.1371/journal.pone.0121121. PMC 4372286. PMID 25803445.