Polymyositis and dermatomyositis history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The hallmark of [ | Polymyositis and dermatomyositis is a multisystem disorder that involves many [[organs]]. The hallmark of polymyositis is symmetric [[muscle weakness]]. The hallmark of dermatomyositis is [[skin]] manifestation. Patients with polymyositis and dermatomyositis may have a positive history of gradual worsening of proximal [[muscle weakness]], past medical history or family history of other [[Autoimmunity|autoimmune diseases]]. Common symptoms include constitutional symptoms, mild [[Myalgia|myalgias]], [[skin]] eruptions, [[Arthralgia|joint pain]], and [[Edema|swelling]]. Less common symptoms of polymyositis and dermatomyositis include [[cough]], [[dyspnea]], [[Aspiration pneumonia|aspiration]], [[dysphagia]], nasal regurgitation, [[Edema|swelling]] of [[Periorbital edema|periorbital]] area, and [[Nail (anatomy)|fingernails]]. | ||
==History and Symptoms== | ==History and Symptoms== | ||
*Polymyositis and dermatomyositis is a multisystem disorder that involves many organs. | *Polymyositis and dermatomyositis is a multisystem disorder that involves many [[organs]].<ref name="KhanChristopher-Stine2011">{{cite journal|last1=Khan|first1=Sabiha|last2=Christopher-Stine|first2=Lisa|title=Polymyositis, Dermatomyositis, and Autoimmune Necrotizing Myopathy: Clinical Features|journal=Rheumatic Disease Clinics of North America|volume=37|issue=2|year=2011|pages=143–158|issn=0889857X|doi=10.1016/j.rdc.2011.01.001}}</ref><ref name="DoblougGaren2015">{{cite journal|last1=Dobloug|first1=Cecilie|last2=Garen|first2=Torhild|last3=Bitter|first3=Helle|last4=Stjärne|first4=Johan|last5=Stenseth|first5=Guri|last6=Grøvle|first6=Lars|last7=Sem|first7=Marthe|last8=Gran|first8=Jan Tore|last9=Molberg|first9=Øyvind|title=Prevalence and clinical characteristics of adult polymyositis and dermatomyositis; data from a large and unselected Norwegian cohort|journal=Annals of the Rheumatic Diseases|volume=74|issue=8|year=2015|pages=1551–1556|issn=0003-4967|doi=10.1136/annrheumdis-2013-205127}}</ref><ref name="ChinoyFertig2007">{{cite journal|last1=Chinoy|first1=H.|last2=Fertig|first2=N.|last3=Oddis|first3=C. V|last4=Ollier|first4=W. E R|last5=Cooper|first5=R. G|title=The diagnostic utility of myositis autoantibody testing for predicting the risk of cancer-associated myositis|journal=Annals of the Rheumatic Diseases|volume=66|issue=10|year=2007|pages=1345–1349|issn=0003-4967|doi=10.1136/ard.2006.068502}}</ref><ref name="DalakasHohlfeld2003">{{cite journal|last1=Dalakas|first1=Marinos C|last2=Hohlfeld|first2=Reinhard|title=Polymyositis and dermatomyositis|journal=The Lancet|volume=362|issue=9388|year=2003|pages=971–982|issn=01406736|doi=10.1016/S0140-6736(03)14368-1}}</ref><ref name="DouglasTazelaar2001">{{cite journal|last1=Douglas|first1=William W.|last2=Tazelaar|first2=Henry D.|last3=Hartman|first3=Thomas E.|last4=Hartman|first4=Robert P.|last5=Decker|first5=Paul A.|last6=Schroeder|first6=Darrell R.|last7=Ryu|first7=Jay H.|title=Polymyositis–Dermatomyositis-associated Interstitial Lung Disease|journal=American Journal of Respiratory and Critical Care Medicine|volume=164|issue=7|year=2001|pages=1182–1185|issn=1073-449X|doi=10.1164/ajrccm.164.7.2103110}}</ref> | ||
*The hallmark of polymyositis is symmetric [[muscle weakness]]. | |||
* | *The hallmark of dermatomyositis is [[skin]] manifestation. | ||
===History=== | ===History=== | ||
Patients with polymyositis and dermatomyositis may have a positive history of: | Patients with polymyositis and dermatomyositis may have a positive history of: | ||
*Gradual worsening of proximal muscle weakness manifested as difficulty climbing stairs, getting up from a chair, carrying heavy groceries, or picking up their children | *Gradual worsening of proximal [[muscle weakness]] manifested as difficulty climbing stairs, getting up from a chair, carrying heavy groceries, or picking up their children | ||
*Past medical history of other autoimmune diseases | *Past medical history of other [[Autoimmunity|autoimmune diseases]] | ||
*Family history of autoimmune diseases | *Family history of [[Autoimmunity|autoimmune diseases]] | ||
===Common Symptoms=== | ===Common Symptoms=== | ||
Common symptoms of polymyositis and dermatomyositis include: | Common symptoms of polymyositis and dermatomyositis include: | ||
*Symmetric [[muscle weakness]] | *Symmetric [[muscle weakness]] manifested as: | ||
*Mild myalgias | **Difficulty raising their arms above the shoulders | ||
*Skin eruptions | **Climbing steps | ||
*Fever | **Rising from sitting | ||
* | *Mild [[Myalgia|myalgias]] | ||
*Feeling of [[contraction]] of the arms and legs | |||
*Joint pain | *[[Skin]] eruptions | ||
*Joint swelling | *[[Fever]] | ||
*[[Fatigue]] | |||
*[[Arthralgia|Joint pain]] | |||
*[[Arthritis|Joint swelling]] | |||
===Less Common Symptoms=== | ===Less Common Symptoms=== | ||
Less common symptoms of polymyositis and dermatomyositis include: | Less common symptoms of polymyositis and dermatomyositis include: | ||
*[ | *[[Weight loss]] | ||
*[ | *[[Cough]] | ||
*[ | *[[Dysphagia|Difficulty swallowing]] | ||
*[[Dyspnea|Shortness of breath]] | |||
*Nasal regurgitation | |||
*[[Aspiration pneumonia|Aspiration]] | |||
*[[Periorbital edema|Periorbital swelling]] | |||
* Fingernails [[Edema|swelling]] | |||
* Splitting of the skin of the [[Finger|fingers]] | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Latest revision as of 19:17, 18 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]
Overview
Polymyositis and dermatomyositis is a multisystem disorder that involves many organs. The hallmark of polymyositis is symmetric muscle weakness. The hallmark of dermatomyositis is skin manifestation. Patients with polymyositis and dermatomyositis may have a positive history of gradual worsening of proximal muscle weakness, past medical history or family history of other autoimmune diseases. Common symptoms include constitutional symptoms, mild myalgias, skin eruptions, joint pain, and swelling. Less common symptoms of polymyositis and dermatomyositis include cough, dyspnea, aspiration, dysphagia, nasal regurgitation, swelling of periorbital area, and fingernails.
History and Symptoms
- Polymyositis and dermatomyositis is a multisystem disorder that involves many organs.[1][2][3][4][5]
- The hallmark of polymyositis is symmetric muscle weakness.
- The hallmark of dermatomyositis is skin manifestation.
History
Patients with polymyositis and dermatomyositis may have a positive history of:
- Gradual worsening of proximal muscle weakness manifested as difficulty climbing stairs, getting up from a chair, carrying heavy groceries, or picking up their children
- Past medical history of other autoimmune diseases
- Family history of autoimmune diseases
Common Symptoms
Common symptoms of polymyositis and dermatomyositis include:
- Symmetric muscle weakness manifested as:
- Difficulty raising their arms above the shoulders
- Climbing steps
- Rising from sitting
- Mild myalgias
- Feeling of contraction of the arms and legs
- Skin eruptions
- Fever
- Fatigue
- Joint pain
- Joint swelling
Less Common Symptoms
Less common symptoms of polymyositis and dermatomyositis include:
- Weight loss
- Cough
- Difficulty swallowing
- Shortness of breath
- Nasal regurgitation
- Aspiration
- Periorbital swelling
- Fingernails swelling
- Splitting of the skin of the fingers
References
- ↑ Khan, Sabiha; Christopher-Stine, Lisa (2011). "Polymyositis, Dermatomyositis, and Autoimmune Necrotizing Myopathy: Clinical Features". Rheumatic Disease Clinics of North America. 37 (2): 143–158. doi:10.1016/j.rdc.2011.01.001. ISSN 0889-857X.
- ↑ Dobloug, Cecilie; Garen, Torhild; Bitter, Helle; Stjärne, Johan; Stenseth, Guri; Grøvle, Lars; Sem, Marthe; Gran, Jan Tore; Molberg, Øyvind (2015). "Prevalence and clinical characteristics of adult polymyositis and dermatomyositis; data from a large and unselected Norwegian cohort". Annals of the Rheumatic Diseases. 74 (8): 1551–1556. doi:10.1136/annrheumdis-2013-205127. ISSN 0003-4967.
- ↑ Chinoy, H.; Fertig, N.; Oddis, C. V; Ollier, W. E R; Cooper, R. G (2007). "The diagnostic utility of myositis autoantibody testing for predicting the risk of cancer-associated myositis". Annals of the Rheumatic Diseases. 66 (10): 1345–1349. doi:10.1136/ard.2006.068502. ISSN 0003-4967.
- ↑ Dalakas, Marinos C; Hohlfeld, Reinhard (2003). "Polymyositis and dermatomyositis". The Lancet. 362 (9388): 971–982. doi:10.1016/S0140-6736(03)14368-1. ISSN 0140-6736.
- ↑ Douglas, William W.; Tazelaar, Henry D.; Hartman, Thomas E.; Hartman, Robert P.; Decker, Paul A.; Schroeder, Darrell R.; Ryu, Jay H. (2001). "Polymyositis–Dermatomyositis-associated Interstitial Lung Disease". American Journal of Respiratory and Critical Care Medicine. 164 (7): 1182–1185. doi:10.1164/ajrccm.164.7.2103110. ISSN 1073-449X.