Polymyositis and dermatomyositis MRI: Difference between revisions

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==Overview==
==Overview==
[[Magnetic resonance imaging|MRI]] from [[muscles]] may be helpful in the diagnosis of polymyositis and dermatomyositis. Findings on [[Magnetic resonance imaging|MRI]] suggestive of polymyositis and dermatomyositis include areas of high signal intensity reflecting an active disease and muscle [[edema]], fatty infiltration of [[Muscle|muscles]], and muscle [[calcification]].


==MRI==
==MRI==
*MRI from [[muscles]] may be helpful in the diagnosis of polymyositis and dermatomyositis.  
*[[Magnetic resonance imaging|MRI]] from [[muscles]] may be helpful in the diagnosis of polymyositis and dermatomyositis.<ref name="KhanChristopher-Stine2011">{{cite journal|last1=Khan|first1=Sabiha|last2=Christopher-Stine|first2=Lisa|title=Polymyositis, Dermatomyositis, and Autoimmune Necrotizing Myopathy: Clinical Features|journal=Rheumatic Disease Clinics of North America|volume=37|issue=2|year=2011|pages=143–158|issn=0889857X|doi=10.1016/j.rdc.2011.01.001}}</ref><ref name="DoblougGaren2015">{{cite journal|last1=Dobloug|first1=Cecilie|last2=Garen|first2=Torhild|last3=Bitter|first3=Helle|last4=Stjärne|first4=Johan|last5=Stenseth|first5=Guri|last6=Grøvle|first6=Lars|last7=Sem|first7=Marthe|last8=Gran|first8=Jan Tore|last9=Molberg|first9=Øyvind|title=Prevalence and clinical characteristics of adult polymyositis and dermatomyositis; data from a large and unselected Norwegian cohort|journal=Annals of the Rheumatic Diseases|volume=74|issue=8|year=2015|pages=1551–1556|issn=0003-4967|doi=10.1136/annrheumdis-2013-205127}}</ref><ref name="ChinoyFertig2007">{{cite journal|last1=Chinoy|first1=H.|last2=Fertig|first2=N.|last3=Oddis|first3=C. V|last4=Ollier|first4=W. E R|last5=Cooper|first5=R. G|title=The diagnostic utility of myositis autoantibody testing for predicting the risk of cancer-associated myositis|journal=Annals of the Rheumatic Diseases|volume=66|issue=10|year=2007|pages=1345–1349|issn=0003-4967|doi=10.1136/ard.2006.068502}}</ref><ref name="DalakasHohlfeld2003">{{cite journal|last1=Dalakas|first1=Marinos C|last2=Hohlfeld|first2=Reinhard|title=Polymyositis and dermatomyositis|journal=The Lancet|volume=362|issue=9388|year=2003|pages=971–982|issn=01406736|doi=10.1016/S0140-6736(03)14368-1}}</ref><ref name="DouglasTazelaar2001">{{cite journal|last1=Douglas|first1=William W.|last2=Tazelaar|first2=Henry D.|last3=Hartman|first3=Thomas E.|last4=Hartman|first4=Robert P.|last5=Decker|first5=Paul A.|last6=Schroeder|first6=Darrell R.|last7=Ryu|first7=Jay H.|title=Polymyositis–Dermatomyositis-associated Interstitial Lung Disease|journal=American Journal of Respiratory and Critical Care Medicine|volume=164|issue=7|year=2001|pages=1182–1185|issn=1073-449X|doi=10.1164/ajrccm.164.7.2103110}}</ref>
*MRI is required for follow-up, and to identify the best site for muscle biopsy.
*MRI is required for follow-up, and to identify the best site for [[muscle biopsy]].
*
*Findings on MRI suggestive of polymyositis and dermatomyositis include:
*Findings on MRI suggestive of polymyositis and dermatomyositis include:
** Areas of high signal intensity reflecting an active disease and muscle edema
** Areas of high signal intensity reflecting an active disease and muscle [[edema]]
** Fatty infiltration of muscles
** Fatty infiltration of [[Muscle|muscles]]
** Muscle calcification
** Muscle [[calcification]]
[[image:Polymyositis-1.JPG|thumb|300px|left|MRI (sagittal STIR) of the cervical spine demonstrates diffuse hyperintensity of the paravertebral muscles. Case courtesy of Dr Daniela Seixas <br>via Radiopaedia.org<ref name="urlPolymyositis | Radiology Case | Radiopaedia.org">{{cite web |url=https://radiopaedia.org/cases/19187 |title=Polymyositis &#124; Radiology Case &#124; Radiopaedia.org |format= |work= |accessdate=}}</ref>]]
[[image:Polymyositis-1.JPG|thumb|300px|left|MRI (sagittal STIR) of the cervical spine demonstrates diffuse hyperintensity of the paravertebral muscles. Case courtesy of Dr Daniela Seixas, Radiopaedia.org<ref name="urlPolymyositis | Radiology Case | Radiopaedia.org">{{cite web |url=https://radiopaedia.org/cases/polymyositis-1 |title=Polymyositis &#124; Radiology Case &#124; Radiopaedia.org |format= |work= |accessdate=}}</ref>]]
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==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Latest revision as of 14:00, 23 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]

Overview

MRI from muscles may be helpful in the diagnosis of polymyositis and dermatomyositis. Findings on MRI suggestive of polymyositis and dermatomyositis include areas of high signal intensity reflecting an active disease and muscle edema, fatty infiltration of muscles, and muscle calcification.

MRI

  • MRI from muscles may be helpful in the diagnosis of polymyositis and dermatomyositis.[1][2][3][4][5]
  • MRI is required for follow-up, and to identify the best site for muscle biopsy.
  • Findings on MRI suggestive of polymyositis and dermatomyositis include:
    • Areas of high signal intensity reflecting an active disease and muscle edema
    • Fatty infiltration of muscles
    • Muscle calcification
MRI (sagittal STIR) of the cervical spine demonstrates diffuse hyperintensity of the paravertebral muscles. Case courtesy of Dr Daniela Seixas, Radiopaedia.org[6]


References

  1. Khan, Sabiha; Christopher-Stine, Lisa (2011). "Polymyositis, Dermatomyositis, and Autoimmune Necrotizing Myopathy: Clinical Features". Rheumatic Disease Clinics of North America. 37 (2): 143–158. doi:10.1016/j.rdc.2011.01.001. ISSN 0889-857X.
  2. Dobloug, Cecilie; Garen, Torhild; Bitter, Helle; Stjärne, Johan; Stenseth, Guri; Grøvle, Lars; Sem, Marthe; Gran, Jan Tore; Molberg, Øyvind (2015). "Prevalence and clinical characteristics of adult polymyositis and dermatomyositis; data from a large and unselected Norwegian cohort". Annals of the Rheumatic Diseases. 74 (8): 1551–1556. doi:10.1136/annrheumdis-2013-205127. ISSN 0003-4967.
  3. Chinoy, H.; Fertig, N.; Oddis, C. V; Ollier, W. E R; Cooper, R. G (2007). "The diagnostic utility of myositis autoantibody testing for predicting the risk of cancer-associated myositis". Annals of the Rheumatic Diseases. 66 (10): 1345–1349. doi:10.1136/ard.2006.068502. ISSN 0003-4967.
  4. Dalakas, Marinos C; Hohlfeld, Reinhard (2003). "Polymyositis and dermatomyositis". The Lancet. 362 (9388): 971–982. doi:10.1016/S0140-6736(03)14368-1. ISSN 0140-6736.
  5. Douglas, William W.; Tazelaar, Henry D.; Hartman, Thomas E.; Hartman, Robert P.; Decker, Paul A.; Schroeder, Darrell R.; Ryu, Jay H. (2001). "Polymyositis–Dermatomyositis-associated Interstitial Lung Disease". American Journal of Respiratory and Critical Care Medicine. 164 (7): 1182–1185. doi:10.1164/ajrccm.164.7.2103110. ISSN 1073-449X.
  6. "Polymyositis | Radiology Case | Radiopaedia.org".