Microscopic polyangiitis epidemiology and demographics: Difference between revisions
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{{Microscopic polyangiitis}} | {{Microscopic polyangiitis}} | ||
{{CMG}}{{APM}}{{AE}}{{ | {{CMG}}{{APM}}{{AE}}{{VKG}} | ||
==Overview== | ==Overview== | ||
The prevalence of Microscopic polyangiitis | The [[prevalence]] of [[Microscopic polyangiitis]] higher in Southern European countries and Asia.The incidence of GPA was similar to that of MPA.MPO‐[[Anti-neutrophil cytoplasmic antibody|ANCAs]] when positive in a patient was a marker of poor [[prognosis]] in the population of patients with AAV. | ||
== Epidemiology == | == Epidemiology == | ||
===Incidence=== | ===Incidence=== | ||
Microscopic polyangiitis | * The [[incidence]] of Microscopic polyangiitis is approximately 3.3 per 100,000 individuals worldwide.<ref name="pmid288814462">{{cite journal |vauthors=Berti A, Cornec D, Crowson CS, Specks U, Matteson EL |title=The Epidemiology of Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis in Olmsted County, Minnesota: A Twenty-Year US Population-Based Study |journal=Arthritis Rheumatol |volume=69 |issue=12 |pages=2338–2350 |date=December 2017 |pmid=28881446 |doi=10.1002/art.40313 |url=}}</ref> | ||
* Microscopic polyangiitis in Europe is seen with higher incidences in Southern countries than in Northern countries. <ref name="pmid20688249">{{cite journal| author=Chung SA, Seo P| title=Microscopic polyangiitis. | journal=Rheum Dis Clin North Am | year= 2010 | volume= 36 | issue= 3 | pages= 545-58 | pmid=20688249 | doi=10.1016/j.rdc.2010.04.003 | pmc=2917831 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20688249 }}</ref> | |||
The incidence | * The incidence of Microscopic polyangiitis is estimated to be 0.59 per 100,000 individuals per year in the United Kingdom.<ref name="pmid22258386">{{cite journal| author=Watts RA, Mooney J, Skinner J, Scott DG, Macgregor AJ| title=The contrasting epidemiology of granulomatosis with polyangiitis (Wegener's) and microscopic polyangiitis. | journal=Rheumatology (Oxford) | year= 2012 | volume= 51 | issue= 5 | pages= 926-31 | pmid=22258386 | doi=10.1093/rheumatology/ker454 | pmc=3465699 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22258386 }}</ref> | ||
During the last two decades the incidences of Microscopic polyangiitis has increased, which | * During the last two decades, the incidences of Microscopic polyangiitis has increased, which may be due to increased testing for various vasculitis as a result of availability of testing for ANCA. | ||
===Prevalence=== | ===Prevalence=== | ||
The prevalence of Microscopic polyangiitis is | * The prevalence of Microscopic polyangiitis is approximately 42.1 per 100,000 individuals worldwide.<ref name="pmid28881446">{{cite journal |vauthors=Berti A, Cornec D, Crowson CS, Specks U, Matteson EL |title=The Epidemiology of Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis in Olmsted County, Minnesota: A Twenty-Year US Population-Based Study |journal=Arthritis Rheumatol |volume=69 |issue=12 |pages=2338–2350 |date=December 2017 |pmid=28881446 |doi=10.1002/art.40313 |url=}}</ref> | ||
== | |||
The | |||
===Age=== | ===Age=== | ||
The age at | * The incidence of Microscopic polyangiitis increases with age; the median age at diagnosis is 60 years.<ref name="MohammadJacobsson2007">{{cite journal|last1=Mohammad|first1=A. J.|last2=Jacobsson|first2=L. T. H.|last3=Mahr|first3=A. D.|last4=Sturfelt|first4=G.|last5=Segelmark|first5=M.|title=Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg Strauss syndrome within a defined population in southern Sweden|journal=Rheumatology|volume=46|issue=8|year=2007|pages=1329–1337|issn=1462-0324|doi=10.1093/rheumatology/kem107}}</ref> | ||
===Gender=== | ===Gender=== | ||
Males are more commonly affected with Microscopic polyangiitis than females (1.8:1). | * Males are more commonly affected with Microscopic polyangiitis than females (1.8:1).<ref name="MohammadJacobsson2007" /> | ||
===Race=== | ===Race=== | ||
Microscopic polyangiitis tends to affect individuals of Asian and Southern European descent. | * Microscopic polyangiitis tends to affect individuals of Asian and Southern European descent.<ref name="pmid21798892">{{cite journal |vauthors=Fujimoto S, Watts RA, Kobayashi S, Suzuki K, Jayne DR, Scott DG, Hashimoto H, Nunoi H |title=Comparison of the epidemiology of anti-neutrophil cytoplasmic antibody-associated vasculitis between Japan and the U.K |journal=Rheumatology (Oxford) |volume=50 |issue=10 |pages=1916–20 |date=October 2011 |pmid=21798892 |doi=10.1093/rheumatology/ker205 |url=}}</ref> | ||
==References== | ==References== | ||
Latest revision as of 17:01, 7 June 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [3]
Overview
The prevalence of Microscopic polyangiitis higher in Southern European countries and Asia.The incidence of GPA was similar to that of MPA.MPO‐ANCAs when positive in a patient was a marker of poor prognosis in the population of patients with AAV.
Epidemiology
Incidence
- The incidence of Microscopic polyangiitis is approximately 3.3 per 100,000 individuals worldwide.[1]
- Microscopic polyangiitis in Europe is seen with higher incidences in Southern countries than in Northern countries. [2]
- The incidence of Microscopic polyangiitis is estimated to be 0.59 per 100,000 individuals per year in the United Kingdom.[3]
- During the last two decades, the incidences of Microscopic polyangiitis has increased, which may be due to increased testing for various vasculitis as a result of availability of testing for ANCA.
Prevalence
- The prevalence of Microscopic polyangiitis is approximately 42.1 per 100,000 individuals worldwide.[4]
Age
- The incidence of Microscopic polyangiitis increases with age; the median age at diagnosis is 60 years.[5]
Gender
- Males are more commonly affected with Microscopic polyangiitis than females (1.8:1).[5]
Race
- Microscopic polyangiitis tends to affect individuals of Asian and Southern European descent.[6]
References
- ↑ Berti A, Cornec D, Crowson CS, Specks U, Matteson EL (December 2017). "The Epidemiology of Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis in Olmsted County, Minnesota: A Twenty-Year US Population-Based Study". Arthritis Rheumatol. 69 (12): 2338–2350. doi:10.1002/art.40313. PMID 28881446.
- ↑ Chung SA, Seo P (2010). "Microscopic polyangiitis". Rheum Dis Clin North Am. 36 (3): 545–58. doi:10.1016/j.rdc.2010.04.003. PMC 2917831. PMID 20688249.
- ↑ Watts RA, Mooney J, Skinner J, Scott DG, Macgregor AJ (2012). "The contrasting epidemiology of granulomatosis with polyangiitis (Wegener's) and microscopic polyangiitis". Rheumatology (Oxford). 51 (5): 926–31. doi:10.1093/rheumatology/ker454. PMC 3465699. PMID 22258386.
- ↑ Berti A, Cornec D, Crowson CS, Specks U, Matteson EL (December 2017). "The Epidemiology of Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis in Olmsted County, Minnesota: A Twenty-Year US Population-Based Study". Arthritis Rheumatol. 69 (12): 2338–2350. doi:10.1002/art.40313. PMID 28881446.
- ↑ 5.0 5.1 Mohammad, A. J.; Jacobsson, L. T. H.; Mahr, A. D.; Sturfelt, G.; Segelmark, M. (2007). "Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg Strauss syndrome within a defined population in southern Sweden". Rheumatology. 46 (8): 1329–1337. doi:10.1093/rheumatology/kem107. ISSN 1462-0324.
- ↑ Fujimoto S, Watts RA, Kobayashi S, Suzuki K, Jayne DR, Scott DG, Hashimoto H, Nunoi H (October 2011). "Comparison of the epidemiology of anti-neutrophil cytoplasmic antibody-associated vasculitis between Japan and the U.K". Rheumatology (Oxford). 50 (10): 1916–20. doi:10.1093/rheumatology/ker205. PMID 21798892.