Oliguria with vomiting: Difference between revisions
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{{CMG}}; {{AE}}{{EG}} | {{CMG}}; {{AE}}{{EG}} | ||
'''Abbreviations:''' [[Arterial blood gas|ABG]] = [[Arterial blood gas|Arterial blood gases]], [[BUN]] = [[Blood urea nitrogen]], [[Complete blood count|CBC]] = [[Complete blood count]], [[Computed tomography|CT]] = [[Computed tomography]], CRP = C - reactive protein, [[ECG]] = [[Electrocardiogram]], ESR = [[Erythrocyte sedimentation rate]], IVP = Intravenous pyelography, [[Renal function|KFT]] = [[Renal function tests|Kidney function test]], GI = Gastrointestinal, GFR = [[Glomerular filtration rate]], [[Magnetic resonance imaging|MRI]] = [[Magnetic resonance imaging]], [[PT]] = [[Prothrombin time]] | '''Abbreviations:''' [[Arterial blood gas|ABG]] = [[Arterial blood gas|Arterial blood gases]], [[BUN]] = [[Blood urea nitrogen]], [[Complete blood count|CBC]] = [[Complete blood count]], [[Computed tomography|CT]] = [[Computed tomography]], CRP = C - reactive protein, [[ECG]] = [[Electrocardiogram]], ESR = [[Erythrocyte sedimentation rate]], IVP = Intravenous pyelography, [[Renal function|KFT]] = [[Renal function tests|Kidney function test]], GI = Gastrointestinal, GFR = [[Glomerular filtration rate]], [[Magnetic resonance imaging|MRI]] = [[Magnetic resonance imaging]], [[PT]] = [[Prothrombin time]] | ||
<small> | |||
{| | {| | ||
! colspan="2" rowspan="3" style="background:#4479BA; color: #FFFFFF;" |Etiology | ! colspan="2" rowspan="3" style="background:#4479BA; color: #FFFFFF;" |Etiology | ||
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! align="center" style="background:#4479BA; color: #FFFFFF;" |Other | ! align="center" style="background:#4479BA; color: #FFFFFF;" |Other | ||
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! rowspan=" | ! rowspan="10" style="background: #DCDCDC; padding: 5px; text-align: center;" |Prerenal causes | ||
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Alcohol poisoning]]<ref name="pmid15589492">{{cite journal |vauthors=Pletcher MJ, Maselli J, Gonzales R |title=Uncomplicated alcohol intoxication in the emergency department: an analysis of the National Hospital Ambulatory Medical Care Survey |journal=Am. J. Med. |volume=117 |issue=11 |pages=863–7 |date=December 2004 |pmid=15589492 |doi=10.1016/j.amjmed.2004.07.042 |url=}}</ref><ref name="pmid2927129">{{cite journal |vauthors=Cherpitel CJ |title=Breath analysis and self-reports as measures of alcohol-related emergency room admissions |journal=J. Stud. Alcohol |volume=50 |issue=2 |pages=155–61 |date=March 1989 |pmid=2927129 |doi= |url=}}</ref> | ! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Alcohol poisoning]]<ref name="pmid15589492">{{cite journal |vauthors=Pletcher MJ, Maselli J, Gonzales R |title=Uncomplicated alcohol intoxication in the emergency department: an analysis of the National Hospital Ambulatory Medical Care Survey |journal=Am. J. Med. |volume=117 |issue=11 |pages=863–7 |date=December 2004 |pmid=15589492 |doi=10.1016/j.amjmed.2004.07.042 |url=}}</ref><ref name="pmid2927129">{{cite journal |vauthors=Cherpitel CJ |title=Breath analysis and self-reports as measures of alcohol-related emergency room admissions |journal=J. Stud. Alcohol |volume=50 |issue=2 |pages=155–61 |date=March 1989 |pmid=2927129 |doi= |url=}}</ref> | ||
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Thiamine]] must be given to prevent [[Wernicke's encephalopathy]] | | style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Thiamine]] must be given to prevent [[Wernicke's encephalopathy]] | ||
|- | |- | ||
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cholera|'''Cholera''']]<ref name="pmid19842974">{{cite journal |vauthors=Weil AA, Khan AI, Chowdhury F, Larocque RC, Faruque AS, Ryan ET, Calderwood SB, Qadri F, Harris JB |title=Clinical outcomes in household contacts of patients with cholera in Bangladesh |journal=Clin. Infect. Dis. |volume=49 |issue=10 |pages=1473–9 |date=November 2009 |pmid=19842974 |pmc=2783773 |doi=10.1086/644779 |url=}}</ref><ref name="pmid4809112">{{cite journal |vauthors=Cash RA, Music SI, Libonati JP, Snyder MJ, Wenzel RP, Hornick RB |title=Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum |journal=J. Infect. Dis. |volume=129 |issue=1 |pages=45–52 |date=January 1974 |pmid=4809112 |doi= |url=}}</ref><ref name="pmid4809112">{{cite journal |vauthors=Cash RA, Music SI, Libonati JP, Snyder MJ, Wenzel RP, Hornick RB |title=Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum |journal=J. Infect. Dis. |volume=129 |issue=1 |pages=45–52 |date=January 1974 |pmid=4809112 |doi= |url=}}</ref><ref name="pmid21696312">{{cite journal |vauthors=Harris JB, Ivers LC, Ferraro MJ |title=Case records of the Massachusetts General Hospital. Case 19-2011. A 4-year-old Haitian boy with vomiting and diarrhea |journal=N. Engl. J. Med. |volume=364 |issue=25 |pages=2452–61 |date=June 2011 |pmid=21696312 |doi=10.1056/NEJMcpc1100927 |url=}}</ref> | ! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cholera|'''Cholera''']]<ref name="pmid19842974">{{cite journal |vauthors=Weil AA, Khan AI, Chowdhury F, Larocque RC, Faruque AS, Ryan ET, Calderwood SB, Qadri F, Harris JB |title=Clinical outcomes in household contacts of patients with cholera in Bangladesh |journal=Clin. Infect. Dis. |volume=49 |issue=10 |pages=1473–9 |date=November 2009 |pmid=19842974 |pmc=2783773 |doi=10.1086/644779 |url=}}</ref><ref name="pmid4809112">{{cite journal |vauthors=Cash RA, Music SI, Libonati JP, Snyder MJ, Wenzel RP, Hornick RB |title=Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum |journal=J. Infect. Dis. |volume=129 |issue=1 |pages=45–52 |date=January 1974 |pmid=4809112 |doi= |url=}}</ref><ref name="pmid4809112">{{cite journal |vauthors=Cash RA, Music SI, Libonati JP, Snyder MJ, Wenzel RP, Hornick RB |title=Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum |journal=J. Infect. Dis. |volume=129 |issue=1 |pages=45–52 |date=January 1974 |pmid=4809112 |doi= |url=}}</ref><ref name="pmid21696312">{{cite journal |vauthors=Harris JB, Ivers LC, Ferraro MJ |title=Case records of the Massachusetts General Hospital. Case 19-2011. A 4-year-old Haitian boy with vomiting and diarrhea |journal=N. Engl. J. Med. |volume=364 |issue=25 |pages=2452–61 |date=June 2011 |pmid=21696312 |doi=10.1056/NEJMcpc1100927 |url=}}</ref> | ||
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hepatorenal syndrome]]<ref name="pmid19776409">{{cite journal |vauthors=Ginès P, Schrier RW |title=Renal failure in cirrhosis |journal=N. Engl. J. Med. |volume=361 |issue=13 |pages=1279–90 |date=September 2009 |pmid=19776409 |doi=10.1056/NEJMra0809139 |url=}}</ref><ref name="pmid8550036">{{cite journal |vauthors=Arroyo V, Ginès P, Gerbes AL, Dudley FJ, Gentilini P, Laffi G, Reynolds TB, Ring-Larsen H, Schölmerich J |title=Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites Club |journal=Hepatology |volume=23 |issue=1 |pages=164–76 |date=January 1996 |pmid=8550036 |doi=10.1002/hep.510230122 |url=}}</ref> | ! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hepatorenal syndrome]]<ref name="pmid19776409">{{cite journal |vauthors=Ginès P, Schrier RW |title=Renal failure in cirrhosis |journal=N. Engl. J. Med. |volume=361 |issue=13 |pages=1279–90 |date=September 2009 |pmid=19776409 |doi=10.1056/NEJMra0809139 |url=}}</ref><ref name="pmid8550036">{{cite journal |vauthors=Arroyo V, Ginès P, Gerbes AL, Dudley FJ, Gentilini P, Laffi G, Reynolds TB, Ring-Larsen H, Schölmerich J |title=Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites Club |journal=Hepatology |volume=23 |issue=1 |pages=164–76 |date=January 1996 |pmid=8550036 |doi=10.1002/hep.510230122 |url=}}</ref> | ||
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |Right ventricular preload, ventricular filling pressures, and cardiac function in [[echocardiography]] | | style="background: #F5F5F5; padding: 5px; text-align: center;" |Right ventricular preload, ventricular filling pressures, and cardiac function in [[echocardiography]] | ||
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Malignant hypertension]]<ref name="pmid23102030">{{cite journal |vauthors=Johnson W, Nguyen ML, Patel R |title=Hypertension crisis in the emergency department |journal=Cardiol Clin |volume=30 |issue=4 |pages=533–43 |date=November 2012 |pmid=23102030 |doi=10.1016/j.ccl.2012.07.011 |url=}}</ref><ref name="pmid16627047">{{cite journal |vauthors=Elliott WJ |title=Clinical features in the management of selected hypertensive emergencies |journal=Prog Cardiovasc Dis |volume=48 |issue=5 |pages=316–25 |date=2006 |pmid=16627047 |doi=10.1016/j.pcad.2006.02.004 |url=}}</ref> | ! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Malignant hypertension]]<ref name="pmid23102030">{{cite journal |vauthors=Johnson W, Nguyen ML, Patel R |title=Hypertension crisis in the emergency department |journal=Cardiol Clin |volume=30 |issue=4 |pages=533–43 |date=November 2012 |pmid=23102030 |doi=10.1016/j.ccl.2012.07.011 |url=}}</ref><ref name="pmid16627047">{{cite journal |vauthors=Elliott WJ |title=Clinical features in the management of selected hypertensive emergencies |journal=Prog Cardiovasc Dis |volume=48 |issue=5 |pages=316–25 |date=2006 |pmid=16627047 |doi=10.1016/j.pcad.2006.02.004 |url=}}</ref> | ||
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |Left atrial enlargement and left ventricular [[hypertrophy|hypertrophy in]] [[echocardiography]] | | style="background: #F5F5F5; padding: 5px; text-align: center;" |Left atrial enlargement and left ventricular [[hypertrophy|hypertrophy in]] [[echocardiography]] | ||
| - | | - | ||
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Peritonitis]]<ref name="pmid97980132">{{cite journal |vauthors=Such J, Runyon BA |title=Spontaneous bacterial peritonitis |journal=Clin. Infect. Dis. |volume=27 |issue=4 |pages=669–74; quiz 675–6 |date=October 1998 |pmid=9798013 |doi= |url=}}</ref><ref name="pmid22106722">{{cite journal |vauthors=Runyon BA |title=Monomicrobial nonneutrocytic bacterascites: a variant of spontaneous bacterial peritonitis |journal=Hepatology |volume=12 |issue=4 Pt 1 |pages=710–5 |date=October 1990 |pmid=2210672 |doi= |url=}}</ref> | ! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Peritonitis]]<ref name="pmid97980132">{{cite journal |vauthors=Such J, Runyon BA |title=Spontaneous bacterial peritonitis |journal=Clin. Infect. Dis. |volume=27 |issue=4 |pages=669–74; quiz 675–6 |date=October 1998 |pmid=9798013 |doi= |url=}}</ref><ref name="pmid22106722">{{cite journal |vauthors=Runyon BA |title=Monomicrobial nonneutrocytic bacterascites: a variant of spontaneous bacterial peritonitis |journal=Hepatology |volume=12 |issue=4 Pt 1 |pages=710–5 |date=October 1990 |pmid=2210672 |doi= |url=}}</ref> | ||
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! align="center" style="background:#4479BA; color: #FFFFFF;" |Comments | ! align="center" style="background:#4479BA; color: #FFFFFF;" |Comments | ||
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! rowspan=" | ! rowspan="7" style="background: #DCDCDC; padding: 5px; text-align: center;" |Renal causes | ||
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Acute interstitial nephritis]]<ref name="pmid11020015">{{cite journal |vauthors=Schwarz A, Krause PH, Kunzendorf U, Keller F, Distler A |title=The outcome of acute interstitial nephritis: risk factors for the transition from acute to chronic interstitial nephritis |journal=Clin. Nephrol. |volume=54 |issue=3 |pages=179–90 |date=September 2000 |pmid=11020015 |doi= |url=}}</ref><ref name="pmid20336051">{{cite journal |vauthors=Praga M, González E |title=Acute interstitial nephritis |journal=Kidney Int. |volume=77 |issue=11 |pages=956–61 |date=June 2010 |pmid=20336051 |doi=10.1038/ki.2010.89 |url=}}</ref> | ! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Acute interstitial nephritis]]<ref name="pmid11020015">{{cite journal |vauthors=Schwarz A, Krause PH, Kunzendorf U, Keller F, Distler A |title=The outcome of acute interstitial nephritis: risk factors for the transition from acute to chronic interstitial nephritis |journal=Clin. Nephrol. |volume=54 |issue=3 |pages=179–90 |date=September 2000 |pmid=11020015 |doi= |url=}}</ref><ref name="pmid20336051">{{cite journal |vauthors=Praga M, González E |title=Acute interstitial nephritis |journal=Kidney Int. |volume=77 |issue=11 |pages=956–61 |date=June 2010 |pmid=20336051 |doi=10.1038/ki.2010.89 |url=}}</ref> | ||
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki> | | style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki> | ||
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Ureter]] or [[Urinary bladder|bladder]] abnormality in voiding cystourethrography | | style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Ureter]] or [[Urinary bladder|bladder]] abnormality in voiding cystourethrography | ||
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</small> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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[[Category:Neurology]] | [[Category:Neurology]] | ||
[[Category:Emergency medicine]] | [[Category:Emergency medicine]] | ||
Latest revision as of 23:00, 29 July 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]
Abbreviations: ABG = Arterial blood gases, BUN = Blood urea nitrogen, CBC = Complete blood count, CT = Computed tomography, CRP = C - reactive protein, ECG = Electrocardiogram, ESR = Erythrocyte sedimentation rate, IVP = Intravenous pyelography, KFT = Kidney function test, GI = Gastrointestinal, GFR = Glomerular filtration rate, MRI = Magnetic resonance imaging, PT = Prothrombin time
Etiology | Clinical manifestations | Paraclinical findings | Comments | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Symptoms and signs | Lab findings | Imaging | ||||||||||||||||||||
Fatigue/
Lethargy |
Thirst | Dizziness/
Confusion |
Muscle weakness/
cramp |
Somatic/
visceral pain |
Vomiting | Diarrhea | Tachypnea | Edema | Blood indices | Renal Funtion test | Electrolytes | Urine analysis | ABG | Other | Ultrasound | X-ray | CT | MRI | Other | |||
Prerenal causes | Alcohol poisoning[1][2] | + | - | +/- | - | +/- | + | +/- | - | - | ↑PT | ↑BUN, ↑Cr (isopropyl alcohol) | ↓Na | Not applicable | ↓HCO3 | LFT | Not applicable | Not applicable | Not applicable | Not applicable | - | Thiamine must be given to prevent Wernicke's encephalopathy |
Cholera[3][4][4][5] | +/- | + | - | - | - | +/- | + | - | - | Leukocytosis, ↑HCT | ↑BUN, ↑Cr | ↓Na, ↑Ca, ↑Mg | Not applicable | ↑Lactate, ↓HCO3 | Stool PCR, Stool culture, Serotyping | Not applicable | Not applicable | Not applicable | Not applicable | - | - | |
Dehydration[6][7] | + | + | - | +/- | - | +/- | +/- | - | - | Not applicable | ↑BUN, ↑Cr | ↓Na, ↑K, ↓Cl | Ketones and glucose, ↑Urine specific gravity | ↑Lactate, ↓HCO3 | Hypoglycemia | Not applicable | Not applicable | Not applicable | Not applicable | - | - | |
Diarrhea and/or vomiting[8][9] | +/- | +/- | - | - | - | + | + | - | - | Leukocytosis with predominant neutrophilia, ↑ ESR | Not applicable | Not applicable | Ketones, Organic acids, Porphobilinogen, Aminolevulinic acid | Not applicable | Stool anion gap, Stool pH < 5.5, Stool culture, Serotyping, Enzyme immunoassay (rotavirus or adenovirus), LFT, Amylase, Lipase | Normal | Not applicable | Not applicable | Not applicable | - | - | |
Drugs/toxins[10][11] | +/- | +/- | +/- | +/- | +/- | +/- | +/- | +/- | +/- | Not applicable | ↑BUN, ↑Cr, ↑CK | ↑K, ↓Mg, ↓Ca, ↓P | Ingested drug, Glucose, Aminoacid, Phosphate, Ketone, Hyaline cast, RBC | ↑Lactate, Metabolic acidosis | Toxicology, Rapid immunoassay | Nephropathy | Radioopaque substances, Ingested drug packets | Not applicable | Not applicable | - | - | |
Hepatorenal syndrome[12][13] | +/- | - | - | - | +/- | +/- | - | - | +/- | Leukocytosis, ↑PT | ↓GFR, ↑BUN, ↑Cr | ↓Na | Proteinuria, Na < 10 mEq/L, Urine osmolality > plasma osmolality | Not applicable | Alpha feto-protein, Cryoglobulinemia | Exclude hydronephrosis and intrinsic renal disease | Not applicable | Not applicable | Not applicable | Right ventricular preload, ventricular filling pressures, and cardiac function in echocardiography | - | |
Malignant hypertension[14][15] | +/- | - | + | - | - | +/- | - | +/- | +/- | Microangiopathic hemolytic anemia | ↑BUN, ↑Cr | ↑Na, ↑K, ↑P | Proteinuria, Microscopic hematuria | Acidosis | Cardiac enzymes, Urinary catecholamines, TSH, ↑Renin | Not applicable | Cardiomegaly, Pulmonary edema, Rib notching, Aortic coarctation, Mediastinal widening, Aortic dissection | Not applicable | Not applicable | Left atrial enlargement and left ventricular hypertrophy in echocardiography | - | |
Peritonitis[16][17] | +/- | - | +/- | - | +/- | +/- | +/- | - | - | Leukocytosis | Not applicable | Not applicable | Not applicable | Not applicable | Ascitic fluid neutrophil count > 500 cells/µL | Not applicable | Not applicable | Not applicable | Not applicable | - | - | |
Shock[18] | +/- | +/- | +/- | +/- | +/- | +/- | - | +/- | - | ↑HCT, ↑PT and aPTT, Eosinophilia, Leukocytosis | ↓GFR, ↑BUN, ↑Cr | Not applicable | Not applicable | ↑Lactate | LFT, ↑BNP, ↑Troponin, D-dimer, Fibrinogen | Pulmonary embolism, Pericardial effusion, Cardiac tamponade, Pneumothorax, Thoracic or abdominal aortic aneurysm in RUSH (Rapid Ultrasound for Shock and Hypotension) | Pneumonia, Pneumothorax, Pulmonary edema, Widened mediastinum, Free air under the diaphragm | Traumatic brain injury, Stroke, Spinal injury, Pneumonia, Pneumothorax, Ruptured aneurysm, Aortic dissection, Pulmonary embolism | Not applicable | - | - | |
Toxic megacolon[19] | +/- | +/- | +/- | - | + | + | +/- | - | - | Leukocytosis, Anemia, ↑ESR and CRP | ↑BUN, ↑Cr | ↓Na | Not applicable | Not applicable | Loss of haustra, Hypoechoic and thick bowel walls, Dilated colon > 6cm, Dilatation of ileal loops | Dilated colon, Free intraperitoneal air | Bowel perforation, Abscess | Not applicable | Not applicable | Endoscopy and colonoscopy | - | |
Etiology | Fatigue/
Lethargy |
Thirst | Dizziness/
Confusion |
Muscle weakness/
cramp |
Somatic/
visceral pain |
Vomiting | Diarrhea | Tachypnea | Edema | Blood indices | Renal Funtion test | Electrolytes | Urine analysis | ABG | Other | Ultrasound | X-ray | CT | MRI | Other | Comments | |
Renal causes | Acute interstitial nephritis[20][21] | +/- | - | +/- | - | +/- | +/- | +/- | +/- | +/- | Eosinophilia | ↑BUN, ↑Cr, ↑FENa | Not applicable | Eosinophiluria, Sterile pyuria, Microscopic hematuria, Proteinuria | Not applicable | ↑Total IgG, ↑IgG4 | Normal-sized kidneys | Not applicable | Not applicable | Not applicable | - | History of long term analgesic use |
Acute tubular necrosis[22][23] | +/- | - | - | - | - | +/- | - | - | +/- | Anemia | ↑BUN, ↑Cr, ↑FENa | ↓Na, ↑K, ↑Mg, ↑P, ↓Ca | Pigmented, muddy brown, granular casts | Not applicable | Not applicable | Obstructive uropathy, Renal size, Cortical thickness, Hydronephrosis | Nephrolithiasis | Nephrolithiasis, Area of obstruction | Nephrolithiasis, Area of obstruction | Loss of tubular cells or the denuded tubules, Swollen tubular cells, Loss of the cell brush border in renal biopsy | Furosemide stress testing for staging | |
Cancer[24][25] | + | - | - | - | +/- | +/- | - | - | +/- | Normocytic or microcytic anemia, Leukocytosis or lymphocytosis, ↑Reticulocytes, Thrombocytopenia | ↓GFR, ↑BUN, ↑Cr, ↓Erythropoietin | ↓Na, ↑K, ↓Mg, ↑P, ↓Ca | Gross hematuria | Not applicable | LFT | Fluid collection and morphological change, Flank mass | Calcification and widened mediastinum, Filling defects in barium contrast | Metastasis and staging, Cystic and solid masses, Lymph node, renal vein, and inferior vena cava involvement | Soft tissue invasion and staging | Malignant cystic lesions percutaneous cyst puncture | Renal cell carcinoma types: Clear cell (75%), Chromophilic (15%), Chromophobic (5%), Oncocytoma (3%), Collecting duct (2%) | |
Congenital kidney disease[26][27][28]
- Agenesis |
+/- | - | - | - | +/- | +/- | - | - | +/- | ↑HCT | ↓GFR | ↓P, ↓Ca | Microalbuminuria, Uricosuria | Not applicable | Genetic testing forADPKD2 | Visualization of kidney cysts | Small kidney cysts (0.5 cm) | Kidney size, Intracranial aneurysms | Not applicable | - | - | |
Endogenous toxins[29][30][31][32][33] | +/- | - | +/- | + | - | +/- | - | - | +/- | Anemia, Thrombocytopenia | ↓GFR, ↑BUN, ↑Cr | ↑K, ↑Urate, ↓Ca | Uricosuria, Hematuria, Myoglobinuria, Casts | Not applicable | Creatine kinase > 1000 U/L | Malignant or cystic lesions, Hydronephrosis, Nephrocalcinosis, Urolithiasis | Not applicable | Urolithiasis, Wilms tumor, Polycystic kidney disease | Not applicable | Ureter or bladder abnormality in voiding cystourethrography | - | |
Hemolytic uremic syndrome[34][35][36] | +/- | - | +/- | +/- | +/- | + | + | - | +/- | Severe anemia, Thrombocytopenia, ↑ aPTT | ↑BUN, ↑Cr | Not applicable | Mild proteinuria, Red blood cells, Red blood cell casts | Not applicable | Schistocytes, ↑FDP and D-dimer, ↑ Bilirubin, ↑LDH, ↓Haptoglobin, Stool culture (for E coli 0157:H7 or shigella), ↓ADAMTS-13 activity | Ruling out obstruction | Not applicable | Not applicable | Not applicable | Diffuse thickening of the glomerular capillary wall, Swelling of endothelial cells, Fibrin thrombi in renal biopsy | - | |
Nephrolithiasis[37][38][39] | - | - | - | - | +/- | +/- | - | - | - | Mild leukocytosis, ↑CRP | ↑BUN, ↑Cr | ↑Na, ↑K, ↑P, ↑Ca, ↑Urate | Gross or microscopic hematuria, Red blood cells, Urinary crystals of calcium oxalate, uric acid, or cystine, Hypercalciuria, Urinary pH > 7 in struvite stones (Proteus, Pseudomonas, Klebsiella), Urinary pH < 5 in uric acid stones | ↓HCO3, Renal tubular acidosis | - | All types of stones are visible, Hydronephrosis, Abdominal aortic aneurysm, Cholelithiasis | Calcium - containing stones, Uric acid or cystine stones, Stone movement | Stone density, size and composition, Hydronephrosis, Nephromegaly, Perinephric fat streaking | Not applicable | Intravenous pyelography (IVP), Renal tomography, Nuclear renal scan | - |
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