Polyarteritis nodosa other imaging findings: Difference between revisions
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==Overview== | ==Overview== | ||
Arteriography is the best imaging study to diagnosis of PAN. Findings on an arteriography diagnostic of PAN include microaneurysm, saccular aneurysm and tortuous vessels showing irregular lumina, segmental luminal narrowing or dilatation, infarctions, vascular irregularity and segmental occlusions. | |||
==Other Imaging Findings== | ==Other Imaging Findings== | ||
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=== Arteriography === | === Arteriography === | ||
* Arteriography is the best imaging study to diagnosis of PAN. | * Arteriography is the best imaging study to diagnosis of PAN. | ||
* Findings on an arteriography diagnostic of PAN include:<ref name="pmid2892931">{{cite journal |vauthors=Ewald EA, Griffin D, McCune WJ |title=Correlation of angiographic abnormalities with disease manifestations and disease severity in polyarteritis nodosa |journal=J. Rheumatol. |volume=14 |issue=5 |pages=952–6 |date=October 1987 |pmid=2892931 |doi= |url=}}</ref><ref name="pmid11158650">{{cite journal |vauthors=Stanson AW, Friese JL, Johnson CM, McKusick MA, Breen JF, Sabater EA, Andrews JC |title=Polyarteritis nodosa: spectrum of angiographic findings |journal=Radiographics |volume=21 |issue=1 |pages=151–9 |date=2001 |pmid=11158650 |doi=10.1148/radiographics.21.1.g01ja16151 |url=}}</ref> | * Findings on an arteriography diagnostic of PAN include:<ref name="pmid2892931">{{cite journal |vauthors=Ewald EA, Griffin D, McCune WJ |title=Correlation of angiographic abnormalities with disease manifestations and disease severity in polyarteritis nodosa |journal=J. Rheumatol. |volume=14 |issue=5 |pages=952–6 |date=October 1987 |pmid=2892931 |doi= |url=}}</ref><ref name="pmid11158650">{{cite journal |vauthors=Stanson AW, Friese JL, Johnson CM, McKusick MA, Breen JF, Sabater EA, Andrews JC |title=Polyarteritis nodosa: spectrum of angiographic findings |journal=Radiographics |volume=21 |issue=1 |pages=151–9 |date=2001 |pmid=11158650 |doi=10.1148/radiographics.21.1.g01ja16151 |url=}}</ref><ref name="pmid12350194">{{cite journal |vauthors=Stone JH |title=Polyarteritis nodosa |journal=JAMA |volume=288 |issue=13 |pages=1632–9 |date=October 2002 |pmid=12350194 |doi= |url=}}</ref> | ||
** Microaneurysms | ** Microaneurysms | ||
*** Pathognomic finding seen in 60-80% patients. | *** Pathognomic finding seen in 60-80% patients. | ||
*** Caused by rupture of a vessel wall due to necrotizing inflammatory process. | *** Caused by rupture of a vessel wall due to [[Necrosis|necrotizing]] [[Inflammation|inflammatory]] process. | ||
*** Most commonly seen at the branching points and bifurcations of arteries. | *** Most commonly seen at the branching points and bifurcations of arteries. | ||
*** Microaneurysms are usually more than 10 in number. | *** Microaneurysms are usually more than 10 in number. | ||
*** Size: 2-5mm | *** Size: 2-5mm | ||
** Saccular aneurysms | ** Saccular [[Aneurysm|aneurysms]] | ||
*** Size: 1-5mm | *** Size: 1-5mm | ||
*** Seen in small and medium sized vessels. | *** Seen in small and medium sized vessels. | ||
Latest revision as of 03:40, 22 May 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Haritha Machavarapu, M.B.B.S.
Overview
Arteriography is the best imaging study to diagnosis of PAN. Findings on an arteriography diagnostic of PAN include microaneurysm, saccular aneurysm and tortuous vessels showing irregular lumina, segmental luminal narrowing or dilatation, infarctions, vascular irregularity and segmental occlusions.
Other Imaging Findings
Arteriography
- Arteriography is the best imaging study to diagnosis of PAN.
- Findings on an arteriography diagnostic of PAN include:[1][2][3]
- Microaneurysms
- Pathognomic finding seen in 60-80% patients.
- Caused by rupture of a vessel wall due to necrotizing inflammatory process.
- Most commonly seen at the branching points and bifurcations of arteries.
- Microaneurysms are usually more than 10 in number.
- Size: 2-5mm
- Saccular aneurysms
- Size: 1-5mm
- Seen in small and medium sized vessels.
- Tortuous vessels showing:
- Irregular lumina
- Segmental luminal narrowing or dilatation
- Infarctions
- Vascular irregularity
- Segmental occlusions
- Microaneurysms
References
- ↑ Ewald EA, Griffin D, McCune WJ (October 1987). "Correlation of angiographic abnormalities with disease manifestations and disease severity in polyarteritis nodosa". J. Rheumatol. 14 (5): 952–6. PMID 2892931.
- ↑ Stanson AW, Friese JL, Johnson CM, McKusick MA, Breen JF, Sabater EA, Andrews JC (2001). "Polyarteritis nodosa: spectrum of angiographic findings". Radiographics. 21 (1): 151–9. doi:10.1148/radiographics.21.1.g01ja16151. PMID 11158650.
- ↑ Stone JH (October 2002). "Polyarteritis nodosa". JAMA. 288 (13): 1632–9. PMID 12350194.