Diabetic nephropathy causes: Difference between revisions
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==Overview== | ==Overview== | ||
Diabetes mellitus both type1 and type 2 is the major cause. It is thought to be due to hyperfiltration through the renal glomeruli. The chances of developing diabetic nephropathy is markedly increased in patients with a diabetic sibling or parent who has diabetic nephropathy. these observations have been seen in both type 1 and type 2 diabetes. The genetic basis underlying the heritability of diabetic nephropathy is not known. | |||
==Causes== | ==Causes== | ||
* | * Diabetes, type 1 or 2 | ||
* | * Persistent, uncontrolled hyperglycemia | ||
* | * Hypertension in the presence of diabetes. | ||
* | * Diabetes with smoking | ||
* | * High blood cholesterol and diabetes | ||
* Genetic factors | |||
==References= | ==References<ref name="pmid29999545">{{cite journal |vauthors=Chang MS, Hsu YH |title=The role of IL-20 in chronic kidney disease and diabetic nephropathy: Pathogenic and therapeutic implications |journal=J. Leukoc. Biol. |volume= |issue= |pages= |date=July 2018 |pmid=29999545 |doi=10.1002/JLB.MR1217-489R |url=}}</ref>== | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 19:01, 26 July 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
Diabetes mellitus both type1 and type 2 is the major cause. It is thought to be due to hyperfiltration through the renal glomeruli. The chances of developing diabetic nephropathy is markedly increased in patients with a diabetic sibling or parent who has diabetic nephropathy. these observations have been seen in both type 1 and type 2 diabetes. The genetic basis underlying the heritability of diabetic nephropathy is not known.
Causes
- Diabetes, type 1 or 2
- Persistent, uncontrolled hyperglycemia
- Hypertension in the presence of diabetes.
- Diabetes with smoking
- High blood cholesterol and diabetes
- Genetic factors
References[1]
- ↑ Chang MS, Hsu YH (July 2018). "The role of IL-20 in chronic kidney disease and diabetic nephropathy: Pathogenic and therapeutic implications". J. Leukoc. Biol. doi:10.1002/JLB.MR1217-489R. PMID 29999545.