Amyloidosis: Difference between revisions

	Amyloidosis Microchapters
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Overview
Historical Perspective
Classification • Primary amyloidosis • Secondary amyloidosis • Familial amyloidosis • Wild-type (senile) amyloidosis • Cardiac amyloidosis • Beta-2 microglobulin related amyloidosis • Gelsolin related amyloidosis • Lysozyme amyloid related amyloidosis • Leucocyte cell-derived chemotaxin 2 related amyloidosis • Fibrinogen A alpha-chain associated amyloidosis
Pathophysiology
Causes
Differentiating Amyloidosis from other Diseases
Epidemiology and Demographics
Risk Factors
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Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
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Case #1
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Latest revision as of 20:03, 5 February 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2], Syed Hassan A. Kazmi BSc, MD [3], Shaghayegh Habibi, M.D.[4]

Synonyms and keywords:

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Amyloidosis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Treatment

Case Studies

Case #1

@@ Line 4: / Line 4: @@
 '''For patient information, click [[Amyloidosis (patient information)|here]]'''
-{{CMG}}; {{AE}} {{SHH}}
+{{CMG}}; {{AE}}{{Sab}}, {{HK}}, {{SHH}}
+{{SK}}
 ==[[Amyloidosis overview|Overview]]==
-== Historical Perspective ==
+==[[Amyloidosis historical perspective|Historical Perspective]]==
-*In 1639, Nicolaus Fontanus autopsied a young man who had ascites, jaundice, liver abscess and splenomegaly and his report has been the first description of amyloidosis.<ref name="pmid218384133">{{cite journal |vauthors=Kyle RA |title=Amyloidosis: a brief history |journal=Amyloid |volume=18 Suppl 1 |issue= |pages=6–7 |date=June 2011 |pmid=21838413 |doi=10.3109/13506129.2011.574354001 |url=}}</ref>
-*In 1854, Rudolph Virchow introduced the term of amyloid as an macroscopic abnormality in some tissues.<ref name="pmid10940217">{{cite journal |vauthors=Sipe JD, Cohen AS |title=Review: history of the amyloid fibril |journal=J. Struct. Biol. |volume=130 |issue=2-3 |pages=88–98 |date=June 2000 |pmid=10940217 |doi=10.1006/jsbi.2000.4221 |url=}}</ref>
-*In 1867, Weber reported the first case of amyloidosis associated with multiple myeloma.<ref name="pmid218384133">{{cite journal |vauthors=Kyle RA |title=Amyloidosis: a brief history |journal=Amyloid |volume=18 Suppl 1 |issue= |pages=6–7 |date=June 2011 |pmid=21838413 |doi=10.3109/13506129.2011.574354001 |url=}}</ref>
-*In 1922, Bennhold introduced Congo red staining of amyloid that remains the gold standard for diagnosis.<ref name="pmid11677276">{{cite journal |vauthors=Khan MF, Falk RH |title=Amyloidosis |journal=Postgrad Med J |volume=77 |issue=913 |pages=686–93 |date=November 2001 |pmid=11677276 |pmc=1742163 |doi= |url=}}</ref>
-*In 1959, Cohen and Calkins used ultrathin sections of amyloidotic tissues and assessed by electron microscopic examination, explained the presence of nonbranching fibrils with indeterminate length and variable width.<ref name="pmid10940217">{{cite journal |vauthors=Sipe JD, Cohen AS |title=Review: history of the amyloid fibril |journal=J. Struct. Biol. |volume=130 |issue=2-3 |pages=88–98 |date=June 2000 |pmid=10940217 |doi=10.1006/jsbi.2000.4221 |url=}}</ref><ref name="pmid218384133">{{cite journal |vauthors=Kyle RA |title=Amyloidosis: a brief history |journal=Amyloid |volume=18 Suppl 1 |issue= |pages=6–7 |date=June 2011 |pmid=21838413 |doi=10.3109/13506129.2011.574354001 |url=}}</ref>
-== Classification ==
+==[[Amyloidosis classification|Classification]]==
-Amyloidosis may be classified based on [[precursor]] of amyloidogenic [[protein]] into different subtypes, include:<ref name="pmid25378951">{{cite journal |vauthors=Real de Asúa D, Costa R, Galván JM, Filigheddu MT, Trujillo D, Cadiñanos J |title=Systemic AA amyloidosis: epidemiology, diagnosis, and management |journal=Clin Epidemiol |volume=6 |issue= |pages=369–77 |date=2014 |pmid=25378951 |pmc=4218891 |doi=10.2147/CLEP.S39981 |url=}}</ref><ref name="pmid24998818">{{cite journal |vauthors=Misumi Y, Ando Y |title=[Classification of amyloidosis] |language=Japanese |journal=Brain Nerve |volume=66 |issue=7 |pages=731–7 |date=July 2014 |pmid=24998818 |doi= |url=}}</ref>
-{| class="wikitable"
-!Type
-!Amyloidogenic protein/ fibril
-!Clinical syndrome
-|-
-|AL
-|Light chains of immunoglobulines (most common type)
-|Monoclonal gammopathy
-|-
-|AA
-|Serum amyloid A protein
-|Chronic inflammatory diseases
-|-
-|AF
-|Mutant transthyretin, A1-apolipoprotein, gelsolin, fibrinogen, etc.
-|Familial polyneuropathy/cardiomyopathy/nephropathy
-|-
-|ATTRwt
-|Wild-type transthyretin
-|Senile restrictive cardiomyopathy _ Transthyretin-related amyloidosis wild-type
-|-
-|AH
-|ß2-microglobulin
-|Long-term hemodialysis
-|}
 ==[[Amyloidosis pathophysiology|Pathophysiology]]==
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 ==[[Amyloidosis causes|Causes]]==
 ==[[Amyloidosis differential diagnosis|Differentiating Amyloidosis from other Diseases]]==
 ==[[Amyloidosis epidemiology and demographics|Epidemiology and Demographics]]==
@@ Line 58: / Line 29: @@
 ==Diagnosis==
-[[Amyloidosis history and symptoms|History and Symptoms]] | [[Amyloidosis physical examination|Physical Examination]] | [[Amyloidosis laboratory findings|Laboratory Findings]] | [[Amyloidosis electrocardiogram|Electrocardiogram]] | [[Amyloidosis chest x ray|Chest X Ray]] | [[Amyloidosis CT|CT]] | [[Amyloidosis MRI|MRI]] |  [[Amyloidosis echocardiography|Echocardiography]] | [[Amyloidosis other imaging findings|Other Imaging Findings]] | [[Amyloidosis other diagnostic studies|Other Diagnostic Studies]]
+[[Amyloidosis diagnostic study of choice|Diagnostic study of choice]] | [[Amyloidosis history and symptoms|History and Symptoms]] | [[Amyloidosis physical examination|Physical Examination]] | [[Amyloidosis laboratory findings|Laboratory Findings]] | [[Amyloidosis electrocardiogram|Electrocardiogram]] | [[Amyloidosis x ray|X-ray]] | [[Amyloidosis echocardiography and ultrasound|Echocardiography and Ultrasound]] | [[Amyloidosis CT scan|CT scan]] | [[Amyloidosis MRI|MRI]] | [[Amyloidosis other imaging findings|Other Imaging Findings]] | [[Amyloidosis other diagnostic studies|Other Diagnostic Studies]]
 ==Treatment==
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 [[Amyloidosis case study one|Case #1]]
-{{Metabolic pathology}}
+[[Category:Disease]]
+[[Category:Cardiology]]
+[[Category:Pulmonology]]
-{{WikiDoc Help Menu}}
+[[Category:Immunology]]
-{{WikiDoc Sources}}
-[[Category:Medicine]]
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Amyloidosis: Difference between revisions

Latest revision as of 20:03, 5 February 2020

Diagnosis

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