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Overview
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Cornelus Roelans of Belgium described in 1484 a child with nephrotic syndrome and “whole body swelling.
== Overview ==
One of the first accurate descriptions of nephrotic syndrome in children was made by Theodore Zwinger of Basel in 1722 (5). He also noted decreased urine output and attributed this to “obstruction and compression of the tubules of the kidney,”  
In 1484, Cornelus Roelans of Belgium described a child with “whole body [[swelling]]” and nephropathy. In 1905, Müller described the term of "nephrosis" for non-inflammatory kidney diseases.
It was finally in 1827 that Richard Bright (1789–1858) was able to put together the triad of generalized edema, proteinuria, and kidney disease, as presenting features of this disease (11)
 
In 1905, the term “nephrosis” was coined by Müller to describe all “non-inflammatory” diseases of the kidney as a substitute for parenchymatous nephritis, contrasting it with exudative and inflammatory disease, which would retain the name nephritis <ref name="pmid27303658">{{cite journal |vauthors=Pal A, Kaskel F |title=History of Nephrotic Syndrome and Evolution of its Treatment |journal=Front Pediatr |volume=4 |issue= |pages=56 |date=2016 |pmid=27303658 |pmc=4885377 |doi=10.3389/fped.2016.00056 |url=}}</ref>
== Historical Perspective ==
* In 1484, Cornelus Roelans of Belgium described a child with “whole body [[swelling]]” and nephropathy.
* In 1722, Theodore Zwinger of Basel described nephrotic syndrome in children, with decreased urine output due to “obstruction and compression of the [[Tubule|tubules]] of the kidney.”  
* In 1827, Richard Bright described the triad of generalized [[edema]], [[proteinuria]], and kidney disease, as features of nephrotic syndrome.
* In 1905, Müller described the term of "nephrosis" for non-inflammatory kidney diseases.<ref name="pmid27303658">{{cite journal |vauthors=Pal A, Kaskel F |title=History of Nephrotic Syndrome and Evolution of its Treatment |journal=Front Pediatr |volume=4 |issue= |pages=56 |date=2016 |pmid=27303658 |pmc=4885377 |doi=10.3389/fped.2016.00056 |url=}}</ref>
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


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Latest revision as of 22:57, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Ali Poyan Mehr, M.D. [2] Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [3]

Overview

In 1484, Cornelus Roelans of Belgium described a child with “whole body swelling” and nephropathy. In 1905, Müller described the term of "nephrosis" for non-inflammatory kidney diseases.

Historical Perspective

  • In 1484, Cornelus Roelans of Belgium described a child with “whole body swelling” and nephropathy.
  • In 1722, Theodore Zwinger of Basel described nephrotic syndrome in children, with decreased urine output due to “obstruction and compression of the tubules of the kidney.”
  • In 1827, Richard Bright described the triad of generalized edema, proteinuria, and kidney disease, as features of nephrotic syndrome.
  • In 1905, Müller described the term of "nephrosis" for non-inflammatory kidney diseases.[1]

References

  1. Pal A, Kaskel F (2016). "History of Nephrotic Syndrome and Evolution of its Treatment". Front Pediatr. 4: 56. doi:10.3389/fped.2016.00056. PMC 4885377. PMID 27303658.