Hemolytic-uremic syndrome history and symptoms: Difference between revisions

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{{HUS}}
{{HUS}}
{{CMG}}; {{AE}}
{{CMG}} {{shyam}}; {{AE}} {{S.G.}}, {{AHS}}


==Overview==
==Overview==
The majority of patients with [disease name] are asymptomatic.
The majority of patients with [[Hemolytic-uremic syndrome|hemolytic uremic syndrome]] ([[Hemolytic-uremic syndrome|HUS]]) are [[asymptomatic]]. It usually start with [[gastrointestinal]] [[prodrome]] including [[bloody diarrhea]] and [[fever]] that may occur 2-7 days before the onset of [[renal failure]]. Other [[Symptom|symptoms]] include [[nausea]], [[vomiting]], [[abdominal pain]] and [[swelling]], decreased [[urination]], [[fatigue]], [[irritability]], and [[swelling]] of body.
 
OR
 
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].


==History and Symptoms==
==History and Symptoms==
*The majority of patients with [disease name] are asymptomatic.
*The [[hallmark]] of [[Hemolytic-uremic syndrome|HUS]] is [[Diarrhea with blood|bloody diarrhea]] [[Dysentery|(dysentery)]].<ref>{{Cite journal
OR
| author = [[R. Bhimma]], [[N. C. Rollins]], [[H. M. Coovadia]] & [[M. Adhikari]]
*The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
  | title = Post-dysenteric hemolytic uremic syndrome in children during an epidemic of Shigella dysentery in Kwazulu/Natal
*Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 
  | journal = [[Pediatric nephrology (Berlin, Germany)]]
===History===
  | volume = 11
Patients with HUS may have a positive history of:
  | issue = 5
 
  | pages = 560–564
<nowiki><ref>{{Cite journal</nowiki>
  | year = 1997
  | author = <nowiki>[[L. Slutsker]]</nowiki>, <nowiki>[[A. A. Ries]]</nowiki>, <nowiki>[[K. D. Greene]]</nowiki>, <nowiki>[[J. G. Wells]]</nowiki>, <nowiki>[[L. Hutwagner]]</nowiki> & <nowiki>[[P. M. Griffin]]</nowiki>
  | month = October
  <nowiki> </nowiki><nowiki>|</nowiki> title = Escherichia coli O157:H7 diarrhea in the United States: clinical and epidemiologic features
  | pmid = 9323280
  <nowiki> </nowiki><nowiki>|</nowiki> journal = <nowiki>[[Annals of internal medicine]]</nowiki>
}}</ref>
  <nowiki> </nowiki><nowiki>|</nowiki> volume = 126
*A positive history of [[Diarrhea with blood|bloody diarrhea]] and [[Abdomen|abdominal]] [[tenderness]] is suggestive of [[HUS]]. The most common [[Symptom|symptoms]] of [[HUS]] include [[Diarrhea with blood|bloody diarrhea]] , [[fever]] and [[gastrointestinal]] complaints. The classic triad of signs/symptoms involves microangiopathic hemolytic anemia, renal failure, and thrombocytopenia.
  <nowiki> </nowiki><nowiki>|</nowiki> issue = 7
  <nowiki> </nowiki><nowiki>|</nowiki> pages = 505–513
  <nowiki> </nowiki><nowiki>|</nowiki> year = 1997
  <nowiki> </nowiki><nowiki>|</nowiki> month = April
  <nowiki> </nowiki><nowiki>|</nowiki> pmid = 9092315
}}<nowiki></ref></nowiki>
   
*Bloody diareha
*[History finding 2]
*[History finding 3]
 
===Common Symptoms===
===Common Symptoms===
Common symptoms of [disease] include:
Symptoms of [[HUS]] include:<ref name=":0">{{Cite journal
*[Symptom 1]
| author = [[T. G. Boyce]], [[D. L. Swerdlow]] & [[P. M. Griffin]]
*[Symptom 2]
| title = Escherichia coli O157:H7 and the hemolytic-uremic syndrome
*[Symptom 3]
| journal = [[The New England journal of medicine]]
| volume = 333
| issue = 6
| pages = 364–368
| year = 1995
| month = August
| doi = 10.1056/NEJM199508103330608
| pmid = 7609755
}}</ref><ref name="pmid9092315">{{cite journal |vauthors=Slutsker L, Ries AA, Greene KD, Wells JG, Hutwagner L, Griffin PM |title=Escherichia coli O157:H7 diarrhea in the United States: clinical and epidemiologic features |journal=Ann. Intern. Med. |volume=126 |issue=7 |pages=505–13 |date=April 1997 |pmid=9092315 |doi= |url=}}</ref><ref>{{Cite journal
| author = [[Phillip I. Tarr]], [[Carrie A. Gordon]] & [[Wayne L. Chandler]]
| title = Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome
| journal = [[Lancet (London, England)]]
| volume = 365
| issue = 9464
| pages = 1073–1086
| year = 2005
| month = March
| doi = 10.1016/S0140-6736(05)71144-2
| pmid = 15781103
}}</ref><ref>{{Cite journal
| author = [[Phillip I. Tarr]], [[Carrie A. Gordon]] & [[Wayne L. Chandler]]
| title = Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome
| journal = [[Lancet (London, England)]]
| volume = 365
| issue = 9464
| pages = 1073–1086
| year = 2005
| month = March
| doi = 10.1016/S0140-6736(05)71144-2
| pmid = 15781103
}}</ref><ref>{{Cite journal
| author = [[James B. Kaper]] & [[Alison D. O'Brien]]
| title = Overview and Historical Perspectives
| journal = [[Microbiology spectrum]]
| volume = 2
| issue = 6
| year = 2014
| month = December
| doi = 10.1128/microbiolspec.EHEC-0028-2014
| pmid = 25590020
}}</ref>
*<nowiki/><nowiki/><nowiki/>[[Diarrhea with blood|Bloody diarrhe]]<nowiki/>[[Diarrhea with blood|a]]
*<nowiki/>[[Abdominal pain]]
*Decreased [[urination]] or [[blood]] in [[urine]]
*[[Vomiting]]
*[[Fatigue]]
*[[Irritability]]
*[[Abdominal]] [[swelling]]
*<nowiki/>[[Blood in the urine]] ([[hematuria]])


===Less Common Symptoms===
===Less Common Symptoms===
Less common symptoms of [disease name] include  
Less common [[symptoms]] of [[Hemolytic-uremic syndrome|HUS]] include:
*[Symptom 1]
*[[Swollen face]]
*[Symptom 2]
*[[Swollen face|Swollen]]  [[Swollen limbs|limbs]]
*[Symptom 3]
*[[Seizure|Seizures]]


==References==
==References==

Latest revision as of 00:33, 21 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [3], Anila Hussain, MD [4]

Overview

The majority of patients with hemolytic uremic syndrome (HUS) are asymptomatic. It usually start with gastrointestinal prodrome including bloody diarrhea and fever that may occur 2-7 days before the onset of renal failure. Other symptoms include nausea, vomiting, abdominal pain and swelling, decreased urination, fatigue, irritability, and swelling of body.

History and Symptoms

Common Symptoms

Symptoms of HUS include:[2][3][4][5][6]

Less Common Symptoms

Less common symptoms of HUS include:

References

  1. ↑ R. Bhimma, N. C. Rollins, H. M. Coovadia & M. Adhikari (1997). "Post-dysenteric hemolytic uremic syndrome in children during an epidemic of Shigella dysentery in Kwazulu/Natal". Pediatric nephrology (Berlin, Germany). 11 (5): 560–564. PMID 9323280. Unknown parameter |month= ignored (help)
  2. ↑ T. G. Boyce, D. L. Swerdlow & P. M. Griffin (1995). "Escherichia coli O157:H7 and the hemolytic-uremic syndrome". The New England journal of medicine. 333 (6): 364–368. doi:10.1056/NEJM199508103330608. PMID 7609755. Unknown parameter |month= ignored (help)
  3. ↑ Slutsker L, Ries AA, Greene KD, Wells JG, Hutwagner L, Griffin PM (April 1997). "Escherichia coli O157:H7 diarrhea in the United States: clinical and epidemiologic features". Ann. Intern. Med. 126 (7): 505–13. PMID 9092315.
  4. ↑ Phillip I. Tarr, Carrie A. Gordon & Wayne L. Chandler (2005). "Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome". Lancet (London, England). 365 (9464): 1073–1086. doi:10.1016/S0140-6736(05)71144-2. PMID 15781103. Unknown parameter |month= ignored (help)
  5. ↑ Phillip I. Tarr, Carrie A. Gordon & Wayne L. Chandler (2005). "Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome". Lancet (London, England). 365 (9464): 1073–1086. doi:10.1016/S0140-6736(05)71144-2. PMID 15781103. Unknown parameter |month= ignored (help)
  6. ↑ James B. Kaper & Alison D. O'Brien (2014). "Overview and Historical Perspectives". Microbiology spectrum. 2 (6). doi:10.1128/microbiolspec.EHEC-0028-2014. PMID 25590020. Unknown parameter |month= ignored (help)

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