Hemolytic-uremic syndrome physical examination: Difference between revisions

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{{HUS}}
{{HUS}}
{{CMG}}; {{AE}} {{AHS}}
{{CMG}}; {{AE}} {{S.G.}}, {{AHS}}


==Overview==
==Overview==
Common physical examination findings of Hemolytic Uremic Syndrome include  include edema and fluid overload, high blood pressure and often sever pallor. Gastrointestinal findings may include abdominal tenderness, distension and guarding. Bruising, purpura, petechiae or oozing from the site of venipuncture may b seen sometimes.
Common [[physical examination]] findings of [[Hemolytic-uremic syndrome|hemolytic uremic syndrome]] ([[Hemolytic-uremic syndrome|HUS]]) include [[edema]] and [[fluid overload]], [[high blood pressure]] and often sever pallor. [[Gastrointestinal]] findings may include [[abdominal tenderness]], [[distension]] and [[Abdominal guarding|guarding]]. [[Bruise|bruising]], [[purpura]], [[Petechia|petechiae]] or oozing from the site of [[venipuncture]] may be seen sometimes.


==Physical Examination==
==Physical Examination==
Physical examination of patients with HUS is usually :<ref>{{Cite journal
[[Physical examination]] of patients with [[Hemolytic-uremic syndrome|HUS]] is usually :<ref>{{Cite journal
  | author = [[Marina Noris]], [[Jessica Caprioli]], [[Elena Bresin]], [[Chiara Mossali]], [[Gaia Pianetti]], [[Sara Gamba]], [[Erica Daina]], [[Chiara Fenili]], [[Federica Castelletti]], [[Annalisa Sorosina]], [[Rossella Piras]], [[Roberta Donadelli]], [[Ramona Maranta]], [[Irene van der Meer]], [[Edward M. Conway]], [[Peter F. Zipfel]], [[Timothy H. Goodship]] & [[Giuseppe Remuzzi]]
  | author = [[Marina Noris]], [[Jessica Caprioli]], [[Elena Bresin]], [[Chiara Mossali]], [[Gaia Pianetti]], [[Sara Gamba]], [[Erica Daina]], [[Chiara Fenili]], [[Federica Castelletti]], [[Annalisa Sorosina]], [[Rossella Piras]], [[Roberta Donadelli]], [[Ramona Maranta]], [[Irene van der Meer]], [[Edward M. Conway]], [[Peter F. Zipfel]], [[Timothy H. Goodship]] & [[Giuseppe Remuzzi]]
  | title = Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype
  | title = Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype
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}}</ref>
}}</ref>


*[[Edema]],
*[[Edema]]


*[[Hypertension]]
*[[Hypertension]]
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===Appearance of the Patient===
===Appearance of the Patient===
*Patients with HUS usually appear pale   
*Patients with [[HUS]] usually appear [[Pallor|pale]]  


===Vital Signs ===
===Vital Signs ===


*fever(in some cases)
*[[Fever]] (in some cases)
*Weak pulse  
*Weak [[pulse]]
*High blood pressure with normal pulse pressure  
*[[High blood pressure]] (with normal [[pulse pressure]])


===Skin===
===Skin===
* Skin examination of patients with HUS is usually [[Pale skin color|pale]]. Bruising, petechiae, purpura or oozing from site of venipuncture seen sometimes.
* Skin [[examination]] of patients with HUS is usually [[Pale skin color|pale]]. [[Bruise|Bruising]], [[Petechia|petechiae]], [[purpura]] or oozing from site of [[venipuncture]] seen sometimes.
===HEENT===
===HEENT===
* HEENT examination of patients with HUS is usually normal.
* HEENT examination of patients with [[Hemolytic-uremic syndrome|HUS]] is usually normal.
===Neck===
===Neck===
* Neck examination of patients with HUS is usually normal.
* Neck examination of patients with [[Hemolytic-uremic syndrome|HUS]] is usually normal.
===Lungs===
===Lungs===
* Pulmonary examination of patients with HUS is usually normal.
* Pulmonary examination of patients with [[Hemolytic-uremic syndrome|HUS]] is usually normal.
*
===Heart===
===Heart===
* Cardiovascular examination of patients with HUS is usually normal.
* Cardiovascular examination of patients with HUS is usually normal.
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*[[Abdominal distention]]  
*[[Abdominal distention]]  
*[[Abdominal tenderness]]   
*[[Abdominal tenderness]]   
*Guarding may be present
*[[Abdominal guarding|Guarding]] may be present


===Back===
===Back===
* Back examination of patients with HUS is usually normal.
* Back examination of patients with [[HUS]] is usually normal.
===Genitourinary===
===Genitourinary===
* Genitourinary examination of patients with  is usually normal.
* Genitourinary examination of patients with  is usually normal
* Hematuria may be present
 
===Neuromuscular===
===Neuromuscular===
* Neuromuscular examination of patients with HUS is usually normal.
* Neuromuscular [[examination]] of patients with [[Hemolytic-uremic syndrome|HUS]] is usually normal.


* Patient is usually oriented to persons, place, and time
* Patient is usually oriented to persons, place, and time
* Altered mental status, some patients are in the coma  
* [[Altered mental state|Altered mental status]], some patients are in the [[coma]]


=== Extremities ===
=== Extremities ===
* Extremities examination of patients with HUS is usually normal.
* Extremities examination of patients with [[Hemolytic-uremic syndrome|HUS]] is usually normal
* [[Pitting edema]] lower [[extremities]]


==References==
==References==

Latest revision as of 00:34, 21 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2], Anila Hussain, MD [3]

Overview

Common physical examination findings of hemolytic uremic syndrome (HUS) include edema and fluid overload, high blood pressure and often sever pallor. Gastrointestinal findings may include abdominal tenderness, distension and guarding. bruising, purpura, petechiae or oozing from the site of venipuncture may be seen sometimes.

Physical Examination

Physical examination of patients with HUS is usually :[1][2][3][4]

  • Pallor (often severe)

Appearance of the Patient

  • Patients with HUS usually appear pale

Vital Signs

Skin

HEENT

  • HEENT examination of patients with HUS is usually normal.

Neck

  • Neck examination of patients with HUS is usually normal.

Lungs

  • Pulmonary examination of patients with HUS is usually normal.

Heart

  • Cardiovascular examination of patients with HUS is usually normal.

Abdomen

Back

  • Back examination of patients with HUS is usually normal.

Genitourinary

  • Genitourinary examination of patients with is usually normal
  • Hematuria may be present

Neuromuscular

Extremities

References

  1. Marina Noris, Jessica Caprioli, Elena Bresin, Chiara Mossali, Gaia Pianetti, Sara Gamba, Erica Daina, Chiara Fenili, Federica Castelletti, Annalisa Sorosina, Rossella Piras, Roberta Donadelli, Ramona Maranta, Irene van der Meer, Edward M. Conway, Peter F. Zipfel, Timothy H. Goodship & Giuseppe Remuzzi (2010). "Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype". Clinical journal of the American Society of Nephrology : CJASN. 5 (10): 1844–1859. doi:10.2215/CJN.02210310. PMID 20595690. Unknown parameter |month= ignored (help)
  2. Marina Noris & Giuseppe Remuzzi (2005). "Hemolytic uremic syndrome". Journal of the American Society of Nephrology : JASN. 16 (4): 1035–1050. doi:10.1681/ASN.2004100861. PMID 15728781. Unknown parameter |month= ignored (help)
  3. Olivia Boyer & Patrick Niaudet (2011). "Hemolytic uremic syndrome: new developments in pathogenesis and treatment". International journal of nephrology. 2011: 908407. doi:10.4061/2011/908407. PMID 21876803.
  4. Sylvie Nathanson, Theresa Kwon, Monique Elmaleh, Marina Charbit, Emma Allain Launay, Jerome Harambat, Muriel Brun, Bruno Ranchin, Flavio Bandin, Sylvie Cloarec, Guylhene Bourdat-Michel, Christine Pietrement, Gerard Champion, Tim Ulinski & Georges Deschenes (2010). "Acute neurological involvement in diarrhea-associated hemolytic uremic syndrome". Clinical journal of the American Society of Nephrology : CJASN. 5 (7): 1218–1228. doi:10.2215/CJN.08921209. PMID 20498239. Unknown parameter |month= ignored (help)

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