Hemolytic-uremic syndrome history and symptoms: Difference between revisions
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*A positive history of [[Diarrhea with blood|bloody diarrhea]] and [[Abdomen|abdominal]] [[tenderness]] is suggestive of [[HUS]]. The most common [[Symptom|symptoms]] of [[HUS]] include [[Diarrhea with blood|bloody diarrhea]] , [[fever]] and [[gastrointestinal]] complaints . | *A positive history of [[Diarrhea with blood|bloody diarrhea]] and [[Abdomen|abdominal]] [[tenderness]] is suggestive of [[HUS]]. The most common [[Symptom|symptoms]] of [[HUS]] include [[Diarrhea with blood|bloody diarrhea]] , [[fever]] and [[gastrointestinal]] complaints. The classic triad of signs/symptoms involves microangiopathic hemolytic anemia, renal failure, and thrombocytopenia. | ||
===Common Symptoms=== | ===Common Symptoms=== | ||
Symptoms of [[HUS]] include:<ref name=":0">{{Cite journal | Symptoms of [[HUS]] include:<ref name=":0">{{Cite journal | ||
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*[[Irritability]] | *[[Irritability]] | ||
*[[Abdominal]] [[swelling]] | *[[Abdominal]] [[swelling]] | ||
*<nowiki/>[[Blood in the urine]] ([[hematuria]] ) | *<nowiki/>[[Blood in the urine]] ([[hematuria]]) | ||
===Less Common Symptoms=== | ===Less Common Symptoms=== | ||
Latest revision as of 00:33, 21 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [3], Anila Hussain, MD [4]
Overview
The majority of patients with hemolytic uremic syndrome (HUS) are asymptomatic. It usually start with gastrointestinal prodrome including bloody diarrhea and fever that may occur 2-7 days before the onset of renal failure. Other symptoms include nausea, vomiting, abdominal pain and swelling, decreased urination, fatigue, irritability, and swelling of body.
History and Symptoms
- The hallmark of HUS is bloody diarrhea (dysentery).[1]
- A positive history of bloody diarrhea and abdominal tenderness is suggestive of HUS. The most common symptoms of HUS include bloody diarrhea , fever and gastrointestinal complaints. The classic triad of signs/symptoms involves microangiopathic hemolytic anemia, renal failure, and thrombocytopenia.
Common Symptoms
Symptoms of HUS include:[2][3][4][5][6]
- Bloody diarrhea
- Abdominal pain
- Decreased urination or blood in urine
- Vomiting
- Fatigue
- Irritability
- Abdominal swelling
- Blood in the urine (hematuria)
Less Common Symptoms
Less common symptoms of HUS include:
References
- ↑ R. Bhimma, N. C. Rollins, H. M. Coovadia & M. Adhikari (1997). "Post-dysenteric hemolytic uremic syndrome in children during an epidemic of Shigella dysentery in Kwazulu/Natal". Pediatric nephrology (Berlin, Germany). 11 (5): 560–564. PMID 9323280. Unknown parameter
|month=ignored (help) - ↑ T. G. Boyce, D. L. Swerdlow & P. M. Griffin (1995). "Escherichia coli O157:H7 and the hemolytic-uremic syndrome". The New England journal of medicine. 333 (6): 364–368. doi:10.1056/NEJM199508103330608. PMID 7609755. Unknown parameter
|month=ignored (help) - ↑ Slutsker L, Ries AA, Greene KD, Wells JG, Hutwagner L, Griffin PM (April 1997). "Escherichia coli O157:H7 diarrhea in the United States: clinical and epidemiologic features". Ann. Intern. Med. 126 (7): 505–13. PMID 9092315.
- ↑ Phillip I. Tarr, Carrie A. Gordon & Wayne L. Chandler (2005). "Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome". Lancet (London, England). 365 (9464): 1073–1086. doi:10.1016/S0140-6736(05)71144-2. PMID 15781103. Unknown parameter
|month=ignored (help) - ↑ Phillip I. Tarr, Carrie A. Gordon & Wayne L. Chandler (2005). "Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome". Lancet (London, England). 365 (9464): 1073–1086. doi:10.1016/S0140-6736(05)71144-2. PMID 15781103. Unknown parameter
|month=ignored (help) - ↑ James B. Kaper & Alison D. O'Brien (2014). "Overview and Historical Perspectives". Microbiology spectrum. 2 (6). doi:10.1128/microbiolspec.EHEC-0028-2014. PMID 25590020. Unknown parameter
|month=ignored (help)