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__NOTOC__
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{{Glucose-6-phosphate dehydrogenase deficiency}}
{{Glucose-6-phosphate dehydrogenase deficiency}}
{{CMG}}; {{AE}} {{MA}}
{{CMG}} {{shyam}}; {{AE}} {{MA}}


==Overview==
==Overview==
There are no established measures for the primary prevention of [disease name].


OR
Effective measures for the primary prevention of G6PD deficency include avoiding triggers.  
 
There are no available vaccines against [disease name].
 
OR
 
Effective measures for the primary prevention of [disease name] include [measure1], [measure2], and [measure3].
 
OR
 
[Vaccine name] vaccine is recommended for [patient population] to prevent [disease name]. Other primary prevention strategies include [strategy 1], [strategy 2], and [strategy 3].


==Primary Prevention==
==Primary Prevention==
There are no established measures for the primary prevention of [disease name].
Effective measures for the primary prevention of G6PD deficiency include:<ref name="pmid27040960">{{cite journal |vauthors=Luzzatto L, Nannelli C, Notaro R |title=Glucose-6-Phosphate Dehydrogenase Deficiency |journal=Hematol. Oncol. Clin. North Am. |volume=30 |issue=2 |pages=373–93 |date=April 2016 |pmid=27040960 |doi=10.1016/j.hoc.2015.11.006 |url=}}</ref>
 
*Avoiding triggers (some foods and drugs):
OR
**Fava beans
 
**Sulfa drugs
There are no available vaccines against [disease name].
**Primiquine
 
**Nitrodurantoin
OR
**Rasburicase
 
Effective measures for the primary prevention of [disease name] include:
*[Measure1]
*[Measure2]
*[Measure3]
 
OR
 
[Vaccine name] vaccine is recommended for [patient population] to prevent [disease name]. Other primary prevention strategies include:
*[Strategy 1]
*[Strategy 2]
*[Strategy 3]


*Administration of vaccines:
**Hepatitis A and B vaccines are recommended for G6PD defeceincy patients to prevent attacks due to infection.<ref name="pmid18159462">{{cite journal |vauthors=Monga A, Makkar RP, Arora A, Mukhopadhyay S, Gupta AK |title=Case report: Acute hepatitis E infection with coexistent glucose-6-phosphate dehydrogenase deficiency |journal=Can J Infect Dis |volume=14 |issue=4 |pages=230–1 |date=July 2003 |pmid=18159462 |pmc=2094938 |doi= |url=}}</ref>
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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{{WH}}
{{WH}}
{{WS}}
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{{Glucose-6-phosphate dehydrogenase deficiency}}
{{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.D.]] [mailto:psingh13579@gmail.com]
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==Overview==
'''Glucose-6-phosphate dehydrogenase (G6PD) deficiency''' is an [[Sex-linked|X-linked recessive]] [[hereditary disease]] featuring abnormally low levels of the [[G6PD]] enzyme, which plays an important role in [[red blood cell]] function. Individuals with the disease may exhibit non-immune [[hemolytic anemia]] in response to a number of causes. It is closely linked to '''[[favism]]''', a disorder characterized by a hemolytic reaction to consumption of [[Vicia faba|broad bean]]s, with a name derived from the [[Italian language|Italian]] name of the broad bean (''fava''). Sometimes the name, [[favism]], is alternatively used to refer to the enzyme
deficiency as a whole.
==Primary Prevention==
* The most important measure is prevention - avoidance of the drugs and foods that cause [[hemolysis]].
*[[Vaccination]] against some common pathogens (e.g. [[hepatitis A]]) may prevent infection-induced attacks.
==References==
{{reflist|2}}
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{{WikiDoc Sources}}
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Latest revision as of 23:41, 19 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [3]

Overview

Effective measures for the primary prevention of G6PD deficency include avoiding triggers.

Primary Prevention

Effective measures for the primary prevention of G6PD deficiency include:[1]

  • Avoiding triggers (some foods and drugs):
    • Fava beans
    • Sulfa drugs
    • Primiquine
    • Nitrodurantoin
    • Rasburicase
  • Administration of vaccines:
    • Hepatitis A and B vaccines are recommended for G6PD defeceincy patients to prevent attacks due to infection.[2]

References

  1. Luzzatto L, Nannelli C, Notaro R (April 2016). "Glucose-6-Phosphate Dehydrogenase Deficiency". Hematol. Oncol. Clin. North Am. 30 (2): 373–93. doi:10.1016/j.hoc.2015.11.006. PMID 27040960.
  2. Monga A, Makkar RP, Arora A, Mukhopadhyay S, Gupta AK (July 2003). "Case report: Acute hepatitis E infection with coexistent glucose-6-phosphate dehydrogenase deficiency". Can J Infect Dis. 14 (4): 230–1. PMC 2094938. PMID 18159462.

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