Iron deficiency anemia medical therapy: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
m (Bot: Removing from Primary care) |
||
| (4 intermediate revisions by 2 users not shown) | |||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Iron deficiency anemia}} | {{Iron deficiency anemia}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{JSS}} | ||
{{PleaseHelp}} | {{PleaseHelp}} | ||
==Overview== | ==Overview== | ||
Treatment of iron deficiency anemia includes iron supplementation and treating the cause of the iron deficiency. Treatment is given according to the severity of anemia. | |||
==Medical Therapy== | ==Medical Therapy== | ||
* Iron supplementation is recommended among patients with iron deficiency anemia. | * Iron supplementation is recommended among patients with iron deficiency anemia<ref name="pmid27913463">{{cite journal| author=Auerbach M, Deloughery T| title=Single-dose intravenous iron for iron deficiency: a new paradigm. | journal=Hematology Am Soc Hematol Educ Program | year= 2016 | volume= 2016 | issue= 1 | pages= 57-66 | pmid=27913463 | doi=10.1182/asheducation-2016.1.57 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27913463 }} </ref><ref name="pmid21705493">{{cite journal| author=Krayenbuehl PA, Battegay E, Breymann C, Furrer J, Schulthess G| title=Intravenous iron for the treatment of fatigue in nonanemic, premenopausal women with low serum ferritin concentration. | journal=Blood | year= 2011 | volume= 118 | issue= 12 | pages= 3222-7 | pmid=21705493 | doi=10.1182/blood-2011-04-346304 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21705493 }} </ref><ref name="pmid11506061">{{cite journal| author=Patterson AJ, Brown WJ, Roberts DC| title=Dietary and supplement treatment of iron deficiency results in improvements in general health and fatigue in Australian women of childbearing age. | journal=J Am Coll Nutr | year= 2001 | volume= 20 | issue= 4 | pages= 337-42 | pmid=11506061 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11506061 }} </ref><ref name="pmid12763985">{{cite journal| author=Verdon F, Burnand B, Stubi CL, Bonard C, Graff M, Michaud A et al.| title=Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial. | journal=BMJ | year= 2003 | volume= 326 | issue= 7399 | pages= 1124 | pmid=12763985 | doi=10.1136/bmj.326.7399.1124 | pmc=156009 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12763985 }} [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=&cmd=prlinks&id=15122863 Review in: ACP J Club. 2004 Mar-Apr;140(2):43] </ref><ref name="pmid28034892">{{cite journal| author=Achebe MM, Gafter-Gvili A| title=How I treat anemia in pregnancy: iron, cobalamin, and folate. | journal=Blood | year= 2017 | volume= 129 | issue= 8 | pages= 940-949 | pmid=28034892 | doi=10.1182/blood-2016-08-672246 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28034892 }} </ref>. | ||
* Pharmacologic medical therapies for iron deficiency anemia include (either) oral iron supplements, parenteral iron supplements, erythropoetin and blood transfusion. | * Pharmacologic medical therapies for iron deficiency anemia include (either) oral iron supplements, parenteral iron supplements, erythropoetin and blood transfusion. | ||
| Line 30: | Line 31: | ||
*** Blood transfusion- Units of packed red blood cells depending on the Hb level. | *** Blood transfusion- Units of packed red blood cells depending on the Hb level. | ||
*** 1 unit given over 3-4 hours. | *** 1 unit given over 3-4 hours. | ||
* Intravenous formulations of iron include ferric carboxymaltose, iron dextran, and iron sucrose. | |||
* Iron deficient individuals need to consume iron rich diet. | * Iron deficient individuals need to consume iron rich diet. | ||
| Line 202: | Line 205: | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
Latest revision as of 22:25, 29 July 2020
|
Iron deficiency anemia Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Iron deficiency anemia medical therapy On the Web |
|
American Roentgen Ray Society Images of Iron deficiency anemia medical therapy |
|
Risk calculators and risk factors for Iron deficiency anemia medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jogeet Singh Sekhon, M.D. [2]
Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.
Overview
Treatment of iron deficiency anemia includes iron supplementation and treating the cause of the iron deficiency. Treatment is given according to the severity of anemia.
Medical Therapy
- Iron supplementation is recommended among patients with iron deficiency anemia[1][2][3][4][5].
- Pharmacologic medical therapies for iron deficiency anemia include (either) oral iron supplements, parenteral iron supplements, erythropoetin and blood transfusion.
Iron deficiency anemia
- 1. Mild anemia
- 1.1 Adults- (Hb -11.0-11.9 g/dL in women and 11.0-12.9 g/dL in men)
- Ferrous sulfate/ferrous gluconate/ferrous fumarate PO 100mg per day for 4 weeks.
- 1.2 Pediatrics- (Hb <9g/dl)
- Ferrous sulfate 3mg/kg PO for 8-12 weeks.
- 1.1 Adults- (Hb -11.0-11.9 g/dL in women and 11.0-12.9 g/dL in men)
- 2. Moderate anemia
- 2.1- Adults( Hb 7-11g/dL)
- Ferric carboxymaltose in a dose of 750mg ( 50mg/ml/min) IV once a week for 2-4 weeks.
- 2.2 Paediatrics- (Hb 5-9g/dl)
- Iron sucrose in a dose of 200mg (30mg/ml/min) IV once a week for 2-4 weeks.
- 2.1- Adults( Hb 7-11g/dL)
- 3. Severe anemia
- 3.1 Adults (Hb <7g/dl in individuals without co morbidities and <8g/dl in patients with heart diseases)
- Blood transfusion- units of packed red blood cellsdepending on the Hb level
- 2 units of blood increase 1 g/dl of Hb.
- 3.2 Paediatrics (Hb <5g/dl)
- Blood transfusion- Units of packed red blood cells depending on the Hb level.
- 1 unit given over 3-4 hours.
- 3.1 Adults (Hb <7g/dl in individuals without co morbidities and <8g/dl in patients with heart diseases)
- Intravenous formulations of iron include ferric carboxymaltose, iron dextran, and iron sucrose.
- Iron deficient individuals need to consume iron rich diet.
- Source of iron rich foods is mentioned below:
Template:Col-2
| Food | Serving size |
Miligrams per serving |
% DV* |
|---|---|---|---|
| Chicken liver (cooked) | 3˝ ounces | 12.8 | 70 |
| Oysters(breaded and fried) | 6 pieces | 4.5 | 25 |
| Beef, chuck (lean, braised) | 3 ounces | 3.2 | 20 |
| Clams (breaded, fried) | 1 cup | 3.0 | 15 |
| Beef tenderloin (roasted) | 3 ounces | 3.0 | 15 |
| Turkey ( dark meat, roasted) | 3˝ ounces | 2.3 | 10 |
| Beef, eye of round (roasted) | 3 ounces | 2.2 | 10 |
| Turkey, light meat (roasted) | 3˝ ounces | 1.6 | 8 |
| Chicken, leg, meat only (roasted) | 3˝ ounces | 1.3 | 6 |
| Tuna, fresh bluefin (cooked) | 3 ounces | 1.1 | 6 |
| Chicken breast (roasted) | 3 ounces | 1.1 | 6 |
| Halibut (cooked) | 3 ounces | 0.9 | 6 |
| Blue crab (cooked) | 3 ounces | 0.8 | 4 |
| Pork loin (broiled) | 3 ounces | 0.8 | 4 |
| Tuna white (canned in water) | 3 ounces | 0.8 | 4 |
| Shrimp (mixed species, cooked) | 4 large | 0.7 | 4 |
| Food | Serving size |
Miligrams per serving |
% DV* |
|---|---|---|---|
| Ready-to-eat cereal (100% iron fortified | cup | 18.0 | 100 |
| Oatmeal, instant, fortified (prepared with water | 1 cup | 10.0 | 60 |
| Soybeans, mature (boiled) | 1 cup | 8.8 | 50 |
| Lentils (boiled) | 1 cup | 6.6 | 35 |
| Kidney beans mature (boiled) | 1 cup | 5.2 | 25 |
| Lima beans large, mature (boiled) | 1 cup | 4.5 | 25 |
| Navy beans mature (boiled) | 1 cup | 4.5 | 25 |
| Ready-to-eat cereal (25% iron fortified) | 1 cup | 4.5 | 25 |
| Black beans mature (boiled) | 1 cup | 3.6 | 20 |
| Pinto beans mature (boiled) | 1 cup | 3.6 | 20 |
| Molasses (blackstrap) | 1 tablespoon | 3.5 | 20 |
| Tofu (raw, firm) | ˝ cup | 3.4 | 20 |
| Spinach (boiled, drained) | ˝ cup | 3.2 | 20 |
| Spinach (canned, drained solids) | ˝ cup | 2.5 | 10 |
| Black-eyed peas (cowpeas) (boiled) | ˝ cup | 1.8 | 10 |
| Spinach (frozen, chopped, boiled) | ˝ cup | 1.9 | 10 |
| Grits (white, enriched | 1 cup | 1.5 | 8 |
| Raisins (seedless, packed) | ˝ cup | 1.5 | 8 |
| Whole wheat bread | 1 slice | 0.9 | 6 |
| White bread (enriched) | 1 slice | 0.9 | 6 |
References
- ↑ Auerbach M, Deloughery T (2016). "Single-dose intravenous iron for iron deficiency: a new paradigm". Hematology Am Soc Hematol Educ Program. 2016 (1): 57–66. doi:10.1182/asheducation-2016.1.57. PMID 27913463.
- ↑ Krayenbuehl PA, Battegay E, Breymann C, Furrer J, Schulthess G (2011). "Intravenous iron for the treatment of fatigue in nonanemic, premenopausal women with low serum ferritin concentration". Blood. 118 (12): 3222–7. doi:10.1182/blood-2011-04-346304. PMID 21705493.
- ↑ Patterson AJ, Brown WJ, Roberts DC (2001). "Dietary and supplement treatment of iron deficiency results in improvements in general health and fatigue in Australian women of childbearing age". J Am Coll Nutr. 20 (4): 337–42. PMID 11506061.
- ↑ Verdon F, Burnand B, Stubi CL, Bonard C, Graff M, Michaud A; et al. (2003). "Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial". BMJ. 326 (7399): 1124. doi:10.1136/bmj.326.7399.1124. PMC 156009. PMID 12763985. Review in: ACP J Club. 2004 Mar-Apr;140(2):43
- ↑ Achebe MM, Gafter-Gvili A (2017). "How I treat anemia in pregnancy: iron, cobalamin, and folate". Blood. 129 (8): 940–949. doi:10.1182/blood-2016-08-672246. PMID 28034892.