Spondyloarthropathy risk factors: Difference between revisions
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Spondyloarthropathy risk factors== | ==Spondyloarthropathy risk factors== | ||
Since the role of genetic in the presence of spondyloarthropathies have been known since several years ago, genetically predisposing individuals are who have HLA-B27 gene, are at risk of developing spondyloarthropathies. | {{Spondyloarthropathy}}Since the role of genetic in the presence of spondyloarthropathies have been known since several years ago, genetically predisposing individuals are who have HLA-B27 gene, are at risk of developing spondyloarthropathies. | ||
The risk of developing spondyloarthropathies in individuals with HLA-B27 gene is 1-2%, however, it can increase to 15-20% if he/she have a first-degree relative with positive HLA-B27 gene and developed spondyloarthropathy. | The risk of developing spondyloarthropathies in individuals with HLA-B27 gene is 1-2%, however, it can increase to 15-20% if he/she have a first-degree relative with positive HLA-B27 gene and developed spondyloarthropathy. | ||
There some genes that are suspicious for their association in SpA | There some genes that are suspicious for their association in SpA, which are included: | ||
* HLA-B27 | |||
** HLA-B*2702 (Association with AS) | |||
** HLA-B*2704 (Association with SpA) | |||
** HLA-B*2705 (Strong association with AS) | |||
** HLA-B*2706 (Very weak association with SpA) | |||
** HLA-B*2709 (AS sparing) | |||
* ERAP1 | |||
* IL23R | |||
* TNFRSF1A | |||
* TRADD | |||
* TNFSF15 | |||
* IL1A | |||
* IL1R2 | |||
* CARD9 | |||
* ANTXR2 | |||
Latest revision as of 12:04, 29 August 2018
Spondyloarthropathy risk factors
|
Spondyloarthropathy Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Spondyloarthropathy risk factors On the Web |
|
American Roentgen Ray Society Images of Spondyloarthropathy risk factors |
|
Risk calculators and risk factors for Spondyloarthropathy risk factors |
Since the role of genetic in the presence of spondyloarthropathies have been known since several years ago, genetically predisposing individuals are who have HLA-B27 gene, are at risk of developing spondyloarthropathies.
The risk of developing spondyloarthropathies in individuals with HLA-B27 gene is 1-2%, however, it can increase to 15-20% if he/she have a first-degree relative with positive HLA-B27 gene and developed spondyloarthropathy.
There some genes that are suspicious for their association in SpA, which are included:
- HLA-B27
- HLA-B*2702 (Association with AS)
- HLA-B*2704 (Association with SpA)
- HLA-B*2705 (Strong association with AS)
- HLA-B*2706 (Very weak association with SpA)
- HLA-B*2709 (AS sparing)
- ERAP1
- IL23R
- TNFRSF1A
- TRADD
- TNFSF15
- IL1A
- IL1R2
- CARD9
- ANTXR2