Thrombotic thrombocytopenic purpura classification: Difference between revisions

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__NOTOC__
__NOTOC__
{{Thrombotic thrombocytopenic purpura}}
{{Thrombotic thrombocytopenic purpura}}
There is no established system for the classification of [disease name].
{{CMG}}; {{AE}} {{S.G.}}
 
OR
 
[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
 
OR
 
[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3]. [Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
 
OR
 
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
 
OR
 
If the staging system involves specific and characteristic findings and features: According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
 
OR
 
The staging of [malignancy name] is based on the [staging system].
 
OR
 
There is no established system for the staging of [malignancy name].
==Classification==
TTP may be classified into several subtypes based on:
#autoantibody against ADAMTS13
Congenital TTP
Inherited TTP
familial TTP
Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34
#gene mutations of  ADAMTS13
 
==References==
{{Reflist|2}}{{WH}}{{WS}}{{CMG}}{{AE}}{{Saeedeh}}
==Overview==
==Overview==
== Classification ==
TTP may be classified according to ''[[ADAMTS13]]'' [[gene]] [[Mutation|mutations]] and [[autoantibody]] against  [[ADAMTS13]] into two subtypes: herditary [[Syndrome|syndromes]], aquired [[Syndrome|syndromes]].
[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
 
OR
 
[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3].
[Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
 
OR
 
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
 
OR
 
If the staging system involves specific and characteristic findings and features:
According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].


==Classification==
==Classification==
 
TTP may be classified into several subtypes based on ''[[ADAMTS13]]'' [[gene]] [[Mutation|mutations]](herditary [[Syndrome|syndromes]]) and [[autoantibody]] against [[ADAMTS13]](aquired [[Syndrome|syndromes]]):<ref name="pmid26581428">{{cite journal |vauthors=Tersteeg C, Verhenne S, Roose E, Schelpe AS, Deckmyn H, De Meyer SF, Vanhoorelbeke K |title=ADAMTS13 and anti-ADAMTS13 autoantibodies in thrombotic thrombocytopenic purpura - current perspectives and new treatment strategies |journal=Expert Rev Hematol |volume=9 |issue=2 |pages=209–21 |date=2016 |pmid=26581428 |doi=10.1586/17474086.2016.1122515 |url=}}</ref><ref>{{Cite journal
There is no established system for the classification of [disease name].
 
OR
 
[Disease name] may be classified according to [classification method] into [number] subtypes/groups:
*[Group1]
*[Group2]
*[Group3]
*[Group4]
 
OR
 
[Disease name] may be classified into [large number > 6] subtypes based on:
*[Classification method 1]
*[Classification method 2]
*[Classification method 3]
 
[Disease name] may be classified into several subtypes based on:
*[Classification method 1]
*[Classification method 2]
*[Classification method 3]
 
OR
 
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
 
OR
 
'''If the staging system involves specific and characteristic findings and features:'''
 
According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
 
OR
 
The staging of [malignancy name] is based on the [staging system].
 
OR
 
There is no established system for the staging of [malignancy name].
 
==References==
{{Reflist|2}}
{{WH}}
{{WS}}
[[Category: (name of the system)]]
* '''Hereditary:''' 
* Congenital TTP
* Inherited TTP
* familial TTP
* Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34 <ref>{{Cite journal
  | author = [[Yoshihiro Fujimura]], [[Masanori Matsumoto]], [[Hideo Yagi]], [[Akira Yoshioka]], [[Taei Matsui]] & [[Koiti Titani]]
  | author = [[Yoshihiro Fujimura]], [[Masanori Matsumoto]], [[Hideo Yagi]], [[Akira Yoshioka]], [[Taei Matsui]] & [[Koiti Titani]]
  | title = Von Willebrand factor-cleaving protease and Upshaw-Schulman syndrome
  | title = Von Willebrand factor-cleaving protease and Upshaw-Schulman syndrome
Line 116: Line 16:
  | month = January
  | month = January
  | pmid = 11843286
  | pmid = 11843286
}}</ref>.
}}</ref>


* '''Acquired:''' Existence of an inhibitory antibody against ADAMS13 due to the variety of conditions.
'''1.Hereditary:''' 
* [[Congenital disorder|Congenital]] TTP
* [[Inherited]] TTP
* [[Familial]] TTP
* Upshaw-Schulman syndrome (USS) is an [[autosomal]] recessive [[disease]] of [[ADAMTS13]] [[gene]] on [[chromosome]] 9q34 .
 
'''2.Acquired'''
* Existence of an [[inhibitory]] [[antibody]] against [[ADAMTS13]] due to the variety of [[Condition|conditions.]]


==References==
==References==
{{reflist|2}}
{{Reflist|2}}
{{WH}}
{{WH}}
{{WS}}
{{WS}}
[[Category:Disease]]
[[Category:Autoimmune diseases]]
[[Category:Hematology]]
[[Category:Rare diseases]]
[[Category:Dermatology]]

Latest revision as of 12:02, 14 March 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]

Overview

TTP may be classified according to ADAMTS13 gene mutations and autoantibody against ADAMTS13 into two subtypes: herditary syndromes, aquired syndromes.

Classification

TTP may be classified into several subtypes based on ADAMTS13 gene mutations(herditary syndromes) and autoantibody against ADAMTS13(aquired syndromes):[1][2]

1.Hereditary:

2.Acquired

References

  1. ↑ Tersteeg C, Verhenne S, Roose E, Schelpe AS, Deckmyn H, De Meyer SF, Vanhoorelbeke K (2016). "ADAMTS13 and anti-ADAMTS13 autoantibodies in thrombotic thrombocytopenic purpura - current perspectives and new treatment strategies". Expert Rev Hematol. 9 (2): 209–21. doi:10.1586/17474086.2016.1122515. PMID 26581428.
  2. ↑ Yoshihiro Fujimura, Masanori Matsumoto, Hideo Yagi, Akira Yoshioka, Taei Matsui & Koiti Titani (2002). "Von Willebrand factor-cleaving protease and Upshaw-Schulman syndrome". International journal of hematology. 75 (1): 25–34. PMID 11843286. Unknown parameter |month= ignored (help)

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